(37 nodes) MHC protein complex binding network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSGALP00000068753	Ig-like domain-containing protein. (159 aa)
	LOC112529934	Ig-like domain-containing protein. (198 aa)
	CD8A-3	Ig-like domain-containing protein. (318 aa)
	LOC107057103	Ig-like domain-containing protein. (271 aa)
	ENSGALP00000072723	Ig-like domain-containing protein. (216 aa)
	ENSGALP00000073054	Ig-like domain-containing protein. (206 aa)
	LOC771880-2	Ig-like domain-containing protein. (214 aa)
	ENSGALP00000073699	Uncharacterized protein. (163 aa)
	ENSGALP00000073878	Ig-like domain-containing protein. (276 aa)
	BLB1	Ig-like domain-containing protein. (325 aa)
	DMA	MHC class II M alpha chain. (263 aa)
	TAPBPL	Uncharacterized protein. (484 aa)
	CD8A	Ig-like domain-containing protein. (207 aa)
	B2M	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (119 aa)
	DMB1	Ig-like domain-containing protein. (310 aa)
	LOC112532337	Ig-like domain-containing protein. (215 aa)
	BLB3	Class II histocompatibility antigen, B-L beta chain. (278 aa)
	BLB2	MHC class II beta chain 2. (263 aa)
	RNASEH2B	Uncharacterized protein. (307 aa)
	DMB2	Ig-like domain-containing protein. (323 aa)
	TCD8AL4	Ig-like domain-containing protein. (212 aa)
	LOC101748499	Ig-like domain-containing protein. (278 aa)
	CD74	Invariant chain isoform p41. (286 aa)
	CD8A-2	Ig-like domain-containing protein. (235 aa)
	ENSGALP00000060244	Ig-like domain-containing protein. (234 aa)
	LOC107049200	Ig-like domain-containing protein. (155 aa)
	ENSGALP00000061280	Ig-like domain-containing protein. (218 aa)
	LOC771804	Ig-like domain-containing protein. (241 aa)
	LOC771880	Ig-like domain-containing protein. (228 aa)
	ENSGALP00000063593	Ig-like domain-containing protein. (234 aa)
	ENSGALP00000064025	Ig-like domain-containing protein. (224 aa)
	LOC107053306	Ig-like domain-containing protein. (212 aa)
	FAM49B	Family with sequence similarity 49 member B. (324 aa)
	CD4	Uncharacterized protein. (487 aa)
	ENSGALP00000066108	Uncharacterized protein. (133 aa)
	BLA	MHC_II_alpha domain-containing protein. (98 aa)
	LOC107049158	Ig-like domain-containing protein. (245 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B2M	BLA	ENSGALP00000039454	ENSGALP00000066361	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	MHC_II_alpha domain-containing protein.	0.598
B2M	BLB1	ENSGALP00000039454	ENSGALP00000053705	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.677
B2M	BLB2	ENSGALP00000039454	ENSGALP00000052055	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	MHC class II beta chain 2.	0.581
B2M	BLB3	ENSGALP00000039454	ENSGALP00000045568	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Class II histocompatibility antigen, B-L beta chain.	0.586
B2M	CD4	ENSGALP00000039454	ENSGALP00000065611	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.712
B2M	CD74	ENSGALP00000039454	ENSGALP00000063230	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Invariant chain isoform p41.	0.832
B2M	CD8A-2	ENSGALP00000039454	ENSGALP00000059832	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.976
B2M	CD8A-3	ENSGALP00000039454	ENSGALP00000071819	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.770
B2M	DMA	ENSGALP00000039454	ENSGALP00000000213	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	MHC class II M alpha chain.	0.576
B2M	DMB1	ENSGALP00000039454	ENSGALP00000040418	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.585
B2M	DMB2	ENSGALP00000039454	ENSGALP00000058881	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.601
B2M	ENSGALP00000073878	ENSGALP00000039454	ENSGALP00000073878	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.565
B2M	LOC101748499	ENSGALP00000039454	ENSGALP00000059816	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.565
B2M	LOC107057103	ENSGALP00000039454	ENSGALP00000072404	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.565
B2M	LOC771804	ENSGALP00000039454	ENSGALP00000061439	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Ig-like domain-containing protein.	0.607
B2M	TAPBPL	ENSGALP00000039454	ENSGALP00000023262	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	Uncharacterized protein.	0.522
BLA	B2M	ENSGALP00000066361	ENSGALP00000039454	MHC_II_alpha domain-containing protein.	Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	0.598
BLA	BLB1	ENSGALP00000066361	ENSGALP00000053705	MHC_II_alpha domain-containing protein.	Ig-like domain-containing protein.	0.877
BLA	BLB2	ENSGALP00000066361	ENSGALP00000052055	MHC_II_alpha domain-containing protein.	MHC class II beta chain 2.	0.987
BLA	BLB3	ENSGALP00000066361	ENSGALP00000045568	MHC_II_alpha domain-containing protein.	Class II histocompatibility antigen, B-L beta chain.	0.877