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| | MYL3 | Myosin light chain 1, cardiac muscle. (194 aa) |
| | CAVIN4 | Caveolae associated protein 4. (357 aa) |
| | FKBP1A | Peptidylprolyl isomerase. (108 aa) |
| | KCNJ8 | Uncharacterized protein. (421 aa) |
| | CMYA5 | Uncharacterized protein. (4413 aa) |
| | MYH1D | Myosin-1B; Muscle contraction. (1940 aa) |
| | SYNPO | Synaptopodin. (1146 aa) |
| | LOC769329 | ANK_REP_REGION domain-containing protein. (359 aa) |
| | LMOD1 | Leiomodin 1. (624 aa) |
| | R4GGX0_CHICK | Uncharacterized protein. (484 aa) |
| | MYBPHL | Myosin-binding protein H; Binds to myosin; probably involved in interaction with thick myofilaments in the A-band; Belongs to the immunoglobulin superfamily. MyBP family. (537 aa) |
| | HSPB1 | Heat shock protein beta-1; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Plays a role in stress resistance and actin organization; Belongs to the small heat shock protein (HSP20) family. (194 aa) |
| | MYOD1 | Myoblast determination protein 1 homolog; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity). (299 aa) |
| | MYBPC1 | Myosin binding protein C, slow type. (1227 aa) |
| | CASQ2 | Calsequestrin-2; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. (406 aa) |
| | MYH15 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1937 aa) |
| | MYL2 | Myosin regulatory light chain 2A, cardiac muscle isoform. (202 aa) |
| | SYNM | IF rod domain-containing protein; Belongs to the intermediate filament family. (1604 aa) |
| | LMOD3 | Leiomodin 3. (524 aa) |
| | JUP | Plakoglobin. (747 aa) |
| | MYOM2 | M-protein, striated muscle; Is a structural constituent of myofibrillar M-band in striated muscle. (1450 aa) |
| | E1C317_CHICK | Uncharacterized protein. (261 aa) |
| | PGM5 | Phosphoglucomutase 5. (567 aa) |
| | PARVB | Parvin beta. (365 aa) |
| | SYNE1 | Uncharacterized protein. (8377 aa) |
| | PDLIM3 | PDZ and LIM domain protein 3. (363 aa) |
| | PYROXD1 | Uncharacterized protein. (500 aa) |
| | CAPZA3 | F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (290 aa) |
| | SYNPO2 | Synaptopodin 2. (1272 aa) |
| | SYNE2 | Spectrin repeat containing nuclear envelope protein 2. (6982 aa) |
| | DES | Desmin; Muscle-specific type III intermediate filament essential for proper muscular structure and function. Plays a crucial role in maintaining the structure of sarcomeres, inter-connecting the Z-disks and forming the myofibrils, linking them not only to the sarcolemmal cytoskeleton, but also to the nucleus and mitochondria, thus providing strength for the muscle fiber during activity. In adult striated muscle they form a fibrous network connecting myofibrils to each other and to the plasma membrane from the periphery of the Z-line structures. (464 aa) |
| | LRRC40 | Leucine-rich repeat-containing protein 40. (603 aa) |
| | ASB2 | Ankyrin repeat and SOCS box containing 2. (645 aa) |
| | GLRX3 | Uncharacterized protein. (328 aa) |
| | PPP1R12A | Protein phosphatase 1 regulatory subunit 12A; Regulates myosin phosphatase activity. (1084 aa) |
| | BAG3 | BCL2 associated athanogene 3. (560 aa) |
| | MTM1 | Myotubularin 1. (603 aa) |
| | SRI | Uncharacterized protein. (297 aa) |
| | NEXN | Nexilin F-actin binding protein. (612 aa) |
| | NRAP | Nebulin related anchoring protein. (1736 aa) |
| | LMOD2 | Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcomere organization in the heart, and for normal heart function (By similarity); Belongs to the tropomodulin family. (552 aa) |
| | CRYAB | Alpha-crystallin B chain; May contribute to the transparency and refractive index of the lens. (174 aa) |
| | ANKRD60 | ANK_REP_REGION domain-containing protein. (151 aa) |
| | ANKRD2 | Ankyrin repeat domain 2 protein. (334 aa) |
| | ANKRD40 | ANK_REP_REGION domain-containing protein. (351 aa) |
| | KCTD6 | Potassium channel tetramerization domain containing 6. (237 aa) |
| | TNNC2 | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (163 aa) |
| | TNNI2 | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (183 aa) |
| | DNAJB6 | DnaJ homolog subfamily B member 6; Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (By similarity). Has a stimulatory effect on the ATPase activity of HSP70 in a dose- dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity (By similarity). (326 aa) |
| | PARVA | Parvin alpha. (336 aa) |
| | KLHL40 | Kelch like family member 40. (587 aa) |
| | MYOZ1 | Myozenin 1. (278 aa) |
| | VCL | Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa) |
| | TMOD3 | Uncharacterized protein. (352 aa) |
| | DCTN4 | Dynactin subunit 4. (467 aa) |
| | MYOM3 | Myomesin 3. (1373 aa) |
| | CSRP3 | Uncharacterized protein. (194 aa) |
| | CAPZB | F-actin-capping protein subunit beta isoforms 1 and 2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization. (277 aa) |
| | MYPN | Myopalladin. (991 aa) |
| | MMP2 | 72 kDa type IV collagenase; Belongs to the peptidase M10A family. (663 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (928 aa) |
| | TMOD1 | Uncharacterized protein. (359 aa) |
| | TNNC1 | Troponin C, slow skeletal and cardiac muscles; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. (215 aa) |
| | MYH1G | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | MYL4 | Myosin light chain, embryonic. (185 aa) |
| | CSRP1 | Cysteine and glycine-rich protein 1; Heat stable protein, that interacts with zyxin/ZYX. May be a component of a signal transduction pathway that mediates adhesion- stimulated changes in gene expression. (192 aa) |
| | TNNT3 | Troponin T, fast skeletal muscle isoforms; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (220 aa) |
| | PDLIM7 | PDZ and LIM domain protein 7; May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. May be involved in bone formation (By similarity). (425 aa) |
| | MYL9 | Myosin regulatory light chain 2, smooth muscle major isoform; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity). (172 aa) |
| | ACTC1 | Actin, alpha cardiac muscle 1, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. (377 aa) |
| | MYH1B | Myosin-1B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1944 aa) |
| | CALD1 | Caldesmon. (524 aa) |
| | MYOZ2 | Uncharacterized protein. (263 aa) |
| | KRT8 | IF rod domain-containing protein; Belongs to the intermediate filament family. (541 aa) |
| | LRRC10B | Leucine rich repeat containing 10B. (269 aa) |
| | PSEN2 | Presenilin-2 CTF subunit; Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the other members of the gamma- secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak channel that allows the passive movement o [...] (455 aa) |
| | MYZAP | Uncharacterized protein. (588 aa) |
| | STUB1 | STIP1 homology and U box-containing protein 1; E3 ubiquitin-protein ligase which targets misfolded chaperone substrates towards proteasomal degradation. Ubiquitinates NOS1 in concert with Hsp70 and Hsp40. Mediates polyubiquitination of DNA polymerase beta (POLB), thereby playing a role in base-excision repair: catalyzes polyubiquitination by amplifying the HUWE1/ARF-BP1-dependent monoubiquitination and leading to POLB-degradation by the proteasome. Mediates polyubiquitination of CYP3A4. May ubiquitinate EPHA2 and regulate the receptor stability and activity through proteasomal degradation. (314 aa) |
| | TMOD2 | Tropomodulin 2. (351 aa) |
| | CAPZA1 | F-actin-capping protein subunit alpha-1; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the formation of epithelial cell junctions. (286 aa) |
| | CAPZA2 | F-actin-capping protein subunit alpha-2; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line. (286 aa) |
| | MYH1A | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | IGFN1 | Uncharacterized protein. (2363 aa) |
| | HOMER1 | Homer scaffold protein 1. (358 aa) |
| | FHL3 | Four and a half LIM domains 3. (279 aa) |
| | CHORDC1 | Cysteine and histidine-rich domain-containing protein 1; Regulates centrosome duplication. (331 aa) |
| | MYOM1 | Uncharacterized protein. (1671 aa) |
| | SYNPO2L | Synaptopodin 2 like. (1080 aa) |
| | SMTNL2 | Smoothelin like 2. (468 aa) |
| | ACTN2 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (By similarity). (923 aa) |
| | SQSTM1 | Sequestosome 1. (453 aa) |
| | CAPN3 | Calpain-3; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family. (810 aa) |
| | ACTA1 | Actin, alpha skeletal muscle. (390 aa) |
| | ACTN4 | Alpha-actinin-4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. Involved in tight junction assembly in epithelial cells. May also function as a transcriptional coactivator, stimulating transcription mediated by nuclear hormone receptors. Belongs to the alpha-actinin family. (1045 aa) |
| | ANK3 | Uncharacterized protein. (4335 aa) |
| | TWF2 | Twinfilin-2; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). (385 aa) |
| | ENSGALP00000051466 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (462 aa) |
| | RYR3 | Uncharacterized protein. (4862 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | TNNT2 | Troponin T, cardiac muscle isoforms; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. (302 aa) |
| | LOC417113 | PID domain-containing protein. (637 aa) |
| | SCN8A | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1978 aa) |
| | RYR2 | Ryanodine receptor 2. (4957 aa) |
| | PDLIM4 | PDZ and LIM domain protein 4; Suppresses SRC activation by recognizing and binding to active SRC and facilitating PTPN13-mediated dephosphorylation of SRC 'Tyr-419' leading to its inactivation. Inactivated SRC dissociates from this protein allowing the initiation of a new SRC inactivation cycle. Involved in reorganization of the actin cytoskeleton (By similarity). In nonmuscle cells, binds to ACTN1 (alpha-actinin-1), increases the affinity of ACTN1 to F-actin (filamentous actin), and promotes formation of actin stress fibers. Involved in regulation of the synaptic AMPA receptor transpo [...] (330 aa) |
| | ACTN1 | Alpha-actinin-1; F-actin cross-linking protein is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. (915 aa) |
| | ILK | Integrin-linked kinase. (452 aa) |
| | MYH1F | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1939 aa) |
| | MYH7 | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1931 aa) |
| | MYH1C | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | MYH11 | Myosin-11; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1978 aa) |
| | FHL2 | Four and a half LIM domains 2. (279 aa) |
| | FBXO32 | Uncharacterized protein. (355 aa) |
| | SIMC1 | SUMO interacting motifs containing 1. (704 aa) |
| | ABRA | Actin binding Rho activating protein. (403 aa) |
| | MYH7B | Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa) |
| | NOS1AP | PID domain-containing protein. (643 aa) |
| | TNNT1 | Uncharacterized protein. (272 aa) |
| | CSRP2 | Cysteine and glycine-rich protein 2; Totally down-regulated in transformed cells. May therefore take part in the control of cell growth and differentiation. (233 aa) |
| | FLNB | Uncharacterized protein. (2652 aa) |
| | CTNNB1 | Uncharacterized protein. (781 aa) |
| | MYH1E | Myosin heavy chain, skeletal muscle, adult; Muscle contraction. Myosin is a protein that binds to F-actin and has ATPase activity that is activated by F-actin. (1939 aa) |
| | MYO7L2 | Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1743 aa) |
| | GGPS1 | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (299 aa) |
| | ENSGALP00000044688 | Myosin_tail_1 domain-containing protein. (234 aa) |
| | SMN | Survival motor neuron protein. (264 aa) |
| | PDLIM1 | PDZ and LIM domain 1. (340 aa) |
| | TWF1 | Uncharacterized protein. (491 aa) |
| | KY | TGc domain-containing protein. (684 aa) |
| | MYOT | Myotilin. (513 aa) |
| | LMAN1L | L-type lectin-like domain-containing protein. (598 aa) |
| | PDLIM5 | Uncharacterized protein. (623 aa) |
| | SCO1 | SCO cytochrome c oxidase assembly protein 1. (558 aa) |
| | ENSGALP00000073678 | Uncharacterized protein. (419 aa) |
| | ENSGALP00000073668 | Myosin_tail_1 domain-containing protein. (254 aa) |
| | TNNI1 | Troponin I1, slow skeletal type. (189 aa) |
| | ENSGALP00000072617 | Uncharacterized protein. (1998 aa) |
| | ENSGALP00000072494 | Uncharacterized protein. (94 aa) |
| | ENSGALP00000072279 | Cnn_1N domain-containing protein. (161 aa) |
| | ENSGALP00000071564 | Uncharacterized protein. (824 aa) |
| | ANK1 | Ankyrin 1. (1984 aa) |
| | TMOD4 | Uncharacterized protein. (570 aa) |
| | ENSGALP00000070799 | SH3 domain-containing protein. (249 aa) |
| | ANK2 | Ankyrin 2. (3970 aa) |
| | SMPX | Uncharacterized protein. (88 aa) |
| | TXLNB | Beta-taxilin; Promotes neurite-outgrowth. May be involved in intracellular vesicle traffic. (693 aa) |
| | ENSGALP00000069842 | Calsequestrin; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. (157 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) |
| | SVIL | Supervillin. (2303 aa) |
| | ABCC9 | ATP binding cassette subfamily C member 9. (1558 aa) |
| | LRRC10 | Leucine rich repeat containing 10. (248 aa) |
| | ENSGALP00000068828 | Uncharacterized protein. (185 aa) |
| | FBXL22 | F-box and leucine rich repeat protein 22. (226 aa) |
| | ENSGALP00000068444 | Uncharacterized protein. (186 aa) |
| | SCN3B | Sodium voltage-gated channel beta subunit 3. (303 aa) |
| | PPP1R12B | Protein phosphatase 1 regulatory subunit. (1047 aa) |
| | SCO2 | SCO cytochrome c oxidase assembly protein 2. (251 aa) |
| | PPP1R12C | Protein phosphatase 1 regulatory subunit. (855 aa) |
| | C7orf57 | Chromosome 7 open reading frame 57. (256 aa) |
| | MYOZ3 | Myozenin 3. (241 aa) |
| | MYBPC2 | Myosin-binding protein C, fast-type; Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F- actin and native thin filaments, and modifies the activity of actin- activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. (254 aa) |
| | FLNA | Uncharacterized protein. (492 aa) |
| | ITGB1BP2 | Integrin subunit beta 1 binding protein 2. (547 aa) |
| | ENSGALP00000067121 | Costars domain-containing protein. (153 aa) |
| | TRIM63 | Tripartite motif containing 63. (509 aa) |
| | FHL5 | Uncharacterized protein. (303 aa) |
| | ENSGALP00000066473 | Uncharacterized protein. (262 aa) |
| | SPTAN1 | Spectrin alpha chain, non-erythrocytic 1; Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization. (2497 aa) |
| | ENSGALP00000066084 | Uncharacterized protein. (370 aa) |
| | DNAJB8 | J domain-containing protein. (70 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1238 aa) |
| | LOC112530475 | B30.2/SPRY domain-containing protein. (311 aa) |
| | NEBL1 | Uncharacterized protein. (2613 aa) |
| | SYNC | Syncoilin, intermediate filament protein. (672 aa) |
