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| | ENSGALP00000068805 | Uncharacterized protein. (165 aa) |
| | GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) |
| | ARMC5 | Uncharacterized protein. (535 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (187 aa) |
| | LOC100858177 | Interferon type A1/A2; Has antiviral activities. (193 aa) |
| | TUSC2 | Uncharacterized protein. (250 aa) |
| | LOC776018 | Uncharacterized protein. (193 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1114 aa) |
| | DOCK10 | Dedicator of cytokinesis 10; Belongs to the DOCK family. (2212 aa) |
| | ENSGALP00000069955 | Uncharacterized protein. (496 aa) |
| | LOC112529934 | Ig-like domain-containing protein. (198 aa) |
| | TBX21 | T-box transcription factor 21. (580 aa) |
| | IFNA3 | Interferon. (193 aa) |
| | SH2D6 | B-cell linker protein; Functions as a central linker protein, downstream of the B- cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR- mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and is required for trafficking of the BCR to late endosomes. However, does not seem to be required for pre-BCR-medi [...] (598 aa) |
| | LOC100857744 | Interferon type A1/A2-like. (193 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (727 aa) |
| | LOC100859032 | Interferon type A1/A2-like. (193 aa) |
| | RIPK3 | Uncharacterized protein. (424 aa) |
| | NFAM1 | Uncharacterized protein. (323 aa) |
| | LOC100857947 | Interferon type A1/A2-like. (193 aa) |
| | IRF9 | IRF tryptophan pentad repeat domain-containing protein. (472 aa) |
| | LOC107050371 | Uncharacterized protein. (1015 aa) |
| | DNAJB9 | J domain-containing protein. (216 aa) |
| | CD8A-3 | Ig-like domain-containing protein. (318 aa) |
| | LOC100857403 | Interferon type A1/A2-like. (193 aa) |
| | CD3D | Ig_4 domain-containing protein. (179 aa) |
| | RORA | Uncharacterized protein. (524 aa) |
| | ENSGALP00000072274 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (126 aa) |
| | ENSGALP00000072433 | Hist_deacetyl domain-containing protein. (266 aa) |
| | ENSGALP00000072723 | Ig-like domain-containing protein. (216 aa) |
| | LOC100858762 | Uncharacterized protein. (193 aa) |
| | ENSGALP00000073054 | Ig-like domain-containing protein. (206 aa) |
| | LOC771880-2 | Ig-like domain-containing protein. (214 aa) |
| | LOC112530959 | STAT_int domain-containing protein. (392 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | ENSGALP00000073699 | Uncharacterized protein. (163 aa) |
| | LEF1 | HMG box domain-containing protein. (412 aa) |
| | STAT6 | SH2 domain-containing protein. (183 aa) |
| | LOC112530215 | Sema domain-containing protein; Belongs to the semaphorin family. (606 aa) |
| | TCF7 | HMG box domain-containing protein. (397 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (356 aa) |
| | CD4 | Uncharacterized protein. (487 aa) |
| | CD79B | B29/Ig-b. (226 aa) |
| | LCK | Proto-oncogene tyrosine-protein kinase LCK; Tyrosine kinase that plays an essential role for the selection and maturation of developing T-cell in the thymus and in mature T-cell function. Is constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors and plays a key role in T-cell antigen receptor(TCR)-linked signal transduction pathways (By similarity); Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (508 aa) |
| | SOX13 | SRY-box transcription factor 13. (666 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | IL12B | Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa) |
| | ZAP70 | Tyrosine-protein kinase. (609 aa) |
| | CBFB | Uncharacterized protein. (187 aa) |
| | STAT5A | Signal transducer and activator of transcription. (764 aa) |
| | MTOR | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2521 aa) |
| | E1C066_CHICK | Uncharacterized protein. (258 aa) |
| | FOXN1 | Forkhead box N1. (636 aa) |
| | ABL1 | Tyrosine-protein kinase. (1111 aa) |
| | ITM2A | BRICHOS domain-containing protein. (251 aa) |
| | CARD11 | Uncharacterized protein. (1170 aa) |
| | IRF8 | Interferon regulatory factor 8; Plays a role as a transcriptional activator or repressor. Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)). Plays a regulatory role in cells of the immune system (By similarity); Belongs to the IRF family. (425 aa) |
| | POU2AF1 | Oct binding factor 1. (256 aa) |
| | BCL6 | B-cell lymphoma 6 protein homolog; Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, repres [...] (708 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; The CD3 complex mediates signal transduction, resulting in T- cell activation and proliferation. Required for normal immune responses. (175 aa) |
| | FADD | Fas associated via death domain. (195 aa) |
| | EGR1 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (709 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (942 aa) |
| | HECTD1 | HECT domain E3 ubiquitin protein ligase 1. (2570 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (286 aa) |
| | TSHR | Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (761 aa) |
| | CMTM7 | MARVEL domain-containing protein. (174 aa) |
| | CCR9 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (145 aa) |
| | LOC768614 | Interferon type A3; Has antiviral activities; Belongs to the alpha/beta interferon family. (193 aa) |
| | EP300 | E1A binding protein p300. (2450 aa) |
| | CG-1B | Beta-galactoside-binding lectin; This protein binds beta-galactoside. May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins. (135 aa) |
| | MFNG | Beta-1,3-N-acetylglucosaminyltransferase. (352 aa) |
| | FBXO7 | F-box domain-containing protein. (526 aa) |
| | BCL2 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1300 aa) |
| | NTRK1 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] (790 aa) |
| | IL7R | Interleukin-7 receptor alpha chain. (460 aa) |
| | IKZF3 | Uncharacterized protein. (509 aa) |
| | PTPN2 | Uncharacterized protein. (597 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (460 aa) |
| | GON4L | Uncharacterized protein. (1044 aa) |
| | RABL3 | Rab-like protein 3; Belongs to the small GTPase superfamily. Rab family. (236 aa) |
| | TRAF3IP2 | SEFIR domain-containing protein. (532 aa) |
| | NFIL3 | Nuclear factor interleukin-3-regulated protein; Acts as a transcriptional regulator (By similarity). Represses PER2 transcription through a recognition sequence in the promoter. Component of the circadian clock that may contribute to the rhythmic expression of PER2 gene in a light-dependent and time-of-day-dependent manner. (458 aa) |
| | GPR89A | Golgi pH regulator; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. (455 aa) |
| | CD8A | Ig-like domain-containing protein. (207 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | RSAD2 | Viperin. (354 aa) |
| | TNFSF13B | TNF family B cell activation factor; Belongs to the tumor necrosis factor family. (288 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | ATM | Non-specific serine/threonine protein kinase. (3050 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) |
| | LEPR | Uncharacterized protein. (1148 aa) |
| | HDAC4 | Histone deacetylase 4; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). (1080 aa) |
| | GPR18 | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (320 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (711 aa) |
| | IFNW1 | Interferon type B; Has antiviral activities; Belongs to the alpha/beta interferon family. (203 aa) |
| | EOMES | T-box_assoc domain-containing protein. (661 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | CDH17 | Uncharacterized protein. (835 aa) |
| | CG-16 | 16 kDa beta-galactoside-binding lectin; This protein binds beta-galactoside. Its physiological function is not yet known. It may be involved in the regulation of differentiation. (126 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning. (363 aa) |
| | CTNNB1 | Uncharacterized protein. (781 aa) |
| | LOC112532337 | Ig-like domain-containing protein. (215 aa) |
| | SP3 | Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription (By similarity). Required for activation of SPARC transcription; Belongs to the Sp1 C2H2-type zinc-finger protein family. (771 aa) |
| | THEMIS | Thymocyte selection associated. (776 aa) |
| | MALT1 | MALT1 paracaspase. (816 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (574 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2820 aa) |
| | ENSGALP00000048186 | Uncharacterized protein. (528 aa) |
| | CCR7 | C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | NKX2-3 | Homeobox domain-containing protein. (328 aa) |
| | NKX2-6 | Homeobox domain-containing protein. (193 aa) |
| | RORC | RAR related orphan receptor C. (461 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa) |
| | FZD7 | Frizzled-7; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (567 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. Activated KIT also transmits signals via [...] (960 aa) |
| | PRR7 | Proline rich 7, synaptic. (231 aa) |
| | IL7 | Interleukin-7. (146 aa) |
| | ABL2 | Tyrosine-protein kinase. (1159 aa) |
| | DCAF1 | DDB1 and CUL4 associated factor 1. (1505 aa) |
| | PCASP3 | Uncharacterized protein. (632 aa) |
| | IL4R | Fibronectin type-III domain-containing protein. (996 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (384 aa) |
| | TPD52 | Uncharacterized protein. (184 aa) |
| | MERTK | Uncharacterized protein. (990 aa) |
| | FLT3 | Fms related tyrosine kinase 3. (877 aa) |
| | SRF | Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa) |
| | CEBPG | Leucine zipper transcription factor. (150 aa) |
| | BAK1 | Uncharacterized protein. (216 aa) |
| | PTPRC | Uncharacterized protein. (1237 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break b [...] (1041 aa) |
| | CHD7 | Chromodomain-helicase-DNA-binding protein 7; Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production (By similarity). (3009 aa) |
| | PCASP2 | Uncharacterized protein. (741 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (884 aa) |
| | IL6R | Uncharacterized protein. (445 aa) |
| | TESPA1 | KRAP_IP3R_bind domain-containing protein. (600 aa) |
| | HLX | H2.0 like homeobox. (431 aa) |
| | SASH3 | Uncharacterized protein. (382 aa) |
| | TCD8AL4 | Ig-like domain-containing protein. (212 aa) |
| | RAG2 | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (535 aa) |
| | CD8A-2 | Ig-like domain-containing protein. (235 aa) |
| | ENSGALP00000060244 | Ig-like domain-containing protein. (234 aa) |
| | LOC100858506 | Interferon alpha. (193 aa) |
| | ENSGALP00000060489 | Hist_deacetyl domain-containing protein. (316 aa) |
| | LOC107049200 | Ig-like domain-containing protein. (155 aa) |
| | ENSGALP00000061280 | Ig-like domain-containing protein. (218 aa) |
| | LOC771804 | Ig-like domain-containing protein. (241 aa) |
| | LOC771880 | Ig-like domain-containing protein. (228 aa) |
| | K4LB56_CHICK | CD150. (333 aa) |
| | CD74 | Invariant chain isoform p41. (286 aa) |
| | ENSGALP00000063593 | Ig-like domain-containing protein. (234 aa) |
| | CD83 | CD83 molecule. (215 aa) |
| | ENSGALP00000064025 | Ig-like domain-containing protein. (224 aa) |
| | LOC107053306 | Ig-like domain-containing protein. (212 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (124 aa) |
| | TNFSF8 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (229 aa) |
| | ENSGALP00000065981 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (164 aa) |
| | ENSGALP00000066108 | Uncharacterized protein. (133 aa) |
| | LOC107049158 | Ig-like domain-containing protein. (245 aa) |
| | LOC100859414 | Uncharacterized protein. (193 aa) |
| | DLL1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (893 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (525 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) |
| | TSC1 | Uncharacterized protein. (275 aa) |
| | ENSGALP00000068753 | Ig-like domain-containing protein. (159 aa) |
| | PTGER4 | Prostaglandin E2 receptor subtype 4; Belongs to the G-protein coupled receptor 1 family. (475 aa) |
