STRINGSTRING
REG4 REG4 OGFOD1 OGFOD1 LGALS2 LGALS2 SPINK7 SPINK7 NPTX2 NPTX2 VTN VTN PIGS PIGS OGFOD2 OGFOD2 CALR3 CALR3 GALNT10 GALNT10 HKDC1 HKDC1 HK1 HK1 GRIFIN GRIFIN PLOD1 PLOD1 EVA1CL EVA1CL P3H1 P3H1 FREM1 FREM1 GALNT18 GALNT18 EVA1C EVA1C PKD1 PKD1 DGCR2 DGCR2 GALNT11 GALNT11 PPP1R3C PPP1R3C P4HA2 P4HA2 ACAN ACAN P4HTM P4HTM MLEC MLEC CD248 CD248 MMR1L3 MMR1L3 MRC1 MRC1 GANC GANC GALNT14 GALNT14 GPCPD1 GPCPD1 GALNT16 GALNT16 SI SI EMC7 EMC7 EGLN3 EGLN3 GALNT3 GALNT3 GALNT2 GALNT2 GALNT15 GALNT15 ALPK1 ALPK1 GNPNAT1 GNPNAT1 CG-1B CG-1B E1C6J6_CHICK E1C6J6_CHICK COLEC11 COLEC11 NRCAM NRCAM LGALS8 LGALS8 GINS4 GINS4 ENDOU ENDOU LOC107049166 LOC107049166 HK2 HK2 SIGLEC1 SIGLEC1 GALNT7 GALNT7 ENSGALP00000068891 ENSGALP00000068891 NCAN NCAN LY75 LY75 OGFOD3 OGFOD3 CHID1 CHID1 CLC2LL CLC2LL EGLN1 EGLN1 COLEC10 COLEC10 GALNT5 GALNT5 PTPRVP PTPRVP SELP SELP PRG4 PRG4 ENSGALP00000070609 ENSGALP00000070609 CLC2DL3 CLC2DL3 LOC107055489 LOC107055489 GALNT1 GALNT1 GALNT12 GALNT12 CLEC3A CLEC3A P3H3 P3H3 PAM PAM MAN2B2 MAN2B2 VCAN VCAN CHODL CHODL CLN5 CLN5 COLEC12 COLEC12 EPM2A EPM2A PLA2R1 PLA2R1 PPP1R3D PPP1R3D CRP CRP SLC2A14 SLC2A14 ALDOB ALDOB MBL2 MBL2 PFKL PFKL P3H4 P3H4 EVA1A EVA1A CLEC18B CLEC18B PTX3 PTX3 LOC769174 LOC769174 STBD1 STBD1 MMR1L4 MMR1L4 LOC771876 LOC771876 LGALSL LGALSL LOC428421 LOC428421 LMAN1L LMAN1L GALNT6 GALNT6 ADGRL3 ADGRL3 P4HA3 P4HA3 CG-16 CG-16 ENDOUL ENDOUL SELE SELE CALR CALR FCN2 FCN2 CRTAP CRTAP P3H2 P3H2 GALNT13 GALNT13 DBH DBH LOC769366 LOC769366 P4HA1 P4HA1 PFKP PFKP MGAM MGAM LOC396477 LOC396477 IGF2R IGF2R ENG ENG PTPRB PTPRB CRYBG2 CRYBG2 GALM GALM AGL AGL CILP2 CILP2 PM5 PM5 MAN2A1 MAN2A1 ENSGALP00000073112 ENSGALP00000073112 AIM1 AIM1 ENSGALP00000053320 ENSGALP00000053320 PHYH PHYH GCK GCK FBXO2 FBXO2 PPP1R3B PPP1R3B ENPP2 ENPP2 LOC423277 LOC423277 LGALS3 LGALS3 HK3 HK3 CLEC19A CLEC19A ADGRL2 ADGRL2 BLEC3 BLEC3 CILP CILP CLEC3B CLEC3B GALNTL6 GALNTL6 PFKM PFKM FBXO44 FBXO44 LMAN2 LMAN2 MAN2A2 MAN2A2 Y-LEC1 Y-LEC1 CLEC17A CLEC17A ENSGALP00000060823 ENSGALP00000060823 BCAN BCAN FCER2 FCER2 GUSB GUSB PLOD2 PLOD2 SIIL SIIL CLC2DL5 CLC2DL5 ENSGALP00000062311 ENSGALP00000062311 LOC101747901 LOC101747901 ENSGALP00000063467 ENSGALP00000063467 LOC107049847 LOC107049847 PGR2/3 PGR2/3 PPP1R3A PPP1R3A SFTPA2 SFTPA2 LMAN2L LMAN2L CRYBG3 CRYBG3 BLEC1 BLEC1 BLEC2 BLEC2 MRC2 MRC2 GALNT17 GALNT17 CD34 CD34 MAN2C1 MAN2C1 GALNT9 GALNT9 GALK1 GALK1 SFTPA1 SFTPA1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
REG4C-type lectin domain-containing protein. (158 aa)
OGFOD12-oxoglutarate and iron dependent oxygenase domain containing 1. (537 aa)
LGALS2Galectin. (131 aa)
SPINK7Ovomucoid; Serine protease inhibitor. Inhibits trypsin. (210 aa)
NPTX2Neuronal pentraxin 2. (434 aa)
VTNSMB domain-containing protein. (453 aa)
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (552 aa)
OGFOD22-oxoglutarate and iron dependent oxygenase domain containing 2. (347 aa)
CALR3Calreticulin. (420 aa)
GALNT10Polypeptide N-acetylgalactosaminyltransferase. (550 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
HK1Uncharacterized protein. (780 aa)
GRIFINGalectin. (139 aa)
PLOD1Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. (730 aa)
EVA1CLUncharacterized protein. (382 aa)
P3H1Prolyl 3-hydroxylase 1; Has prolyl 3-hydroxylase activity catalyzing the post- translational formation of 3-hydroxyproline in -Xaa-Pro-Gly-sequences in collagens, especially types IV and V. May be involved in the secretoty pathway of cells. Has growth suppressive activity in fibroblasts (By similarity); Belongs to the leprecan family. (725 aa)
FREM1FRAS1 related extracellular matrix 1. (2184 aa)
GALNT18Polypeptide N-acetylgalactosaminyltransferase. (607 aa)
EVA1CEva-1 homolog C. (435 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4382 aa)
DGCR2DiGeorge syndrome critical region gene 2. (544 aa)
GALNT11Polypeptide N-acetylgalactosaminyltransferase. (608 aa)
PPP1R3CProtein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (314 aa)
P4HA2Prolyl 4-hydroxylase subunit alpha-2; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. (536 aa)
ACANAggrecan core protein; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region. May play a regulatory role in the matrix assembly of the cartilage. (2089 aa)
P4HTMProlyl 4-hydroxylase, transmembrane. (496 aa)
MLECMalectin. (277 aa)
CD248Uncharacterized protein. (556 aa)
MMR1L3Uncharacterized protein. (1415 aa)
MRC1Uncharacterized protein. (1458 aa)
GANCGal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. (914 aa)
GALNT14Polypeptide N-acetylgalactosaminyltransferase. (553 aa)
GPCPD1Uncharacterized protein. (678 aa)
GALNT16Polypeptide N-acetylgalactosaminyltransferase. (563 aa)
SIUncharacterized protein. (1709 aa)
EMC7ER membrane protein complex subunit 7. (246 aa)
EGLN3Egl-9 family hypoxia inducible factor 3. (241 aa)
GALNT3Polypeptide N-acetylgalactosaminyltransferase. (632 aa)
GALNT2Polypeptide N-acetylgalactosaminyltransferase. (570 aa)
GALNT15Polypeptide N-acetylgalactosaminyltransferase. (646 aa)
ALPK1Alpha kinase 1. (1228 aa)
GNPNAT1Glucosamine 6-phosphate N-acetyltransferase. (190 aa)
CG-1BBeta-galactoside-binding lectin; This protein binds beta-galactoside. May participate in host antiviral defense through specific interaction with glycans on the viral envelope glycoproteins. (135 aa)
E1C6J6_CHICKUncharacterized protein. (251 aa)
COLEC11Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...] (271 aa)
NRCAMNeuronal cell adhesion molecule; This protein is a cell adhesion molecule involved in neuron- neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Specifically involved in the development of optic fibres in the retina; Belongs to the immunoglobulin superfamily. L1/neurofascin/NgCAM family. (1836 aa)
LGALS8Galectin. (315 aa)
GINS4Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (307 aa)
ENDOUEndonuclease, poly(U) specific. (356 aa)
LOC107049166Uncharacterized protein. (573 aa)
HK2Uncharacterized protein. (1245 aa)
SIGLEC1Uncharacterized protein. (606 aa)
GALNT7Polypeptide N-acetylgalactosaminyltransferase. (654 aa)
ENSGALP00000068891Uncharacterized protein. (208 aa)
NCANUncharacterized protein. (1325 aa)
LY75Uncharacterized protein. (1732 aa)
OGFOD32-oxoglutarate and iron dependent oxygenase domain containing 3. (323 aa)
CHID1Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (393 aa)
CLC2LLC-type lectin domain-containing protein. (327 aa)
EGLN1Uncharacterized protein. (443 aa)
COLEC10Collectin-10; Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration. (277 aa)
GALNT5Glyco_trans_2-like domain-containing protein. (282 aa)
PTPRVPUncharacterized protein. (2415 aa)
SELPUncharacterized protein. (578 aa)
PRG4Uncharacterized protein. (370 aa)
ENSGALP00000070609Uncharacterized protein. (335 aa)
CLC2DL3C-type lectin domain-containing protein. (443 aa)
LOC107055489C-type lectin domain-containing protein. (203 aa)
GALNT1Polypeptide N-acetylgalactosaminyltransferase. (559 aa)
GALNT12Polypeptide N-acetylgalactosaminyltransferase. (587 aa)
CLEC3AC-type lectin domain-containing protein. (193 aa)
P3H3Prolyl 3-hydroxylase 3. (716 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (970 aa)
MAN2B2Alpha-mannosidase. (1046 aa)
VCANVersican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. (3559 aa)
CHODLChondrolectin. (291 aa)
CLN5Uncharacterized protein. (339 aa)
COLEC12Collectin-12; Scavenger receptor that displays several functions associated with host defense. Binds to carbohydrates (By similarity). (892 aa)
EPM2ALaforin. (319 aa)
PLA2R1Uncharacterized protein. (1459 aa)
PPP1R3DProtein phosphatase 1 regulatory subunit 3D. (312 aa)
CRPPentaxin. (227 aa)
SLC2A14Solute carrier family 2, facilitated glucose transporter member 3; Facilitative glucose transporter that can also mediate the uptake of various other monosaccharides across the cell membrane. Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate. Does not mediate fructose transport; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. (496 aa)
ALDOBFructose-bisphosphate aldolase B. (364 aa)
MBL2Mannose-binding protein; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. (254 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
P3H4Prolyl 3-hydroxylase family member 4 (non-enzymatic). (434 aa)
EVA1AUncharacterized protein. (478 aa)
CLEC18BUncharacterized protein. (435 aa)
PTX3LamGL domain-containing protein. (433 aa)
LOC769174C-type lectin domain-containing protein. (233 aa)
STBD1Starch binding domain 1. (290 aa)
MMR1L4Uncharacterized protein. (1448 aa)
LOC771876MRC1L-D. (1256 aa)
LGALSLGalectin-related protein; Does not bind lactose, and may not bind carbohydrates. (171 aa)
LOC428421Uncharacterized protein. (1441 aa)
LMAN1LL-type lectin-like domain-containing protein. (598 aa)
GALNT6Polypeptide N-acetylgalactosaminyltransferase. (621 aa)
ADGRL3Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1519 aa)
P4HA3Prolyl 4-hydroxylase subunit alpha 3. (402 aa)
CG-1616 kDa beta-galactoside-binding lectin; This protein binds beta-galactoside. Its physiological function is not yet known. It may be involved in the regulation of differentiation. (126 aa)
ENDOULXendoU domain-containing protein. (289 aa)
SELEUncharacterized protein. (141 aa)
CALRCalreticulin. (416 aa)
FCN2Fibrinogen C-terminal domain-containing protein. (399 aa)
CRTAPCartilage-associated protein; Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues; Belongs to the leprecan family. (393 aa)
P3H2Prolyl 3-hydroxylase 2; Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (By similarity). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity). Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1. Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline. Has no activity on substrates that lack 4-hydroxyproline in the third position (By similarity). (694 aa)
GALNT13Polypeptide N-acetylgalactosaminyltransferase. (557 aa)
DBHDopamine beta-hydroxylase. (584 aa)
LOC769366C-type lectin domain-containing protein. (274 aa)
P4HA1Prolyl 4-hydroxylase subunit alpha-1; Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins; Belongs to the P4HA family. (536 aa)
PFKP6-phosphofructokinase; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade "E" sub-subfamily. (831 aa)
MGAMP-type domain-containing protein. (1706 aa)
LOC396477Hepatic lectin; Hepatic lectin is a membrane receptor protein that recognizes and binds exposed N-acetylglucosamine moieties of plasma glycoproteins, thus mediating their clearance (from the circulation) and endocytosis. (207 aa)
IGF2RFibronectin type-II domain-containing protein. (2561 aa)
ENGZP domain-containing protein. (714 aa)
PTPRBProtein tyrosine phosphatase receptor type B. (2119 aa)
CRYBG2Crystallin beta-gamma domain containing 2; Belongs to the beta/gamma-crystallin family. (1493 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (344 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1530 aa)
CILP2Cartilage intermediate layer protein 2. (1095 aa)
PM5Uncharacterized protein. (1208 aa)
MAN2A1Alpha-mannosidase. (1153 aa)
ENSGALP00000073112Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (245 aa)
AIM1Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (1213 aa)
ENSGALP00000053320C-type lectin domain-containing protein. (185 aa)
PHYHPhytanoyl-CoA 2-hydroxylase. (328 aa)
GCKPhosphotransferase. (465 aa)
FBXO2F-box protein 2. (247 aa)
PPP1R3BProtein phosphatase 1 regulatory subunit. (301 aa)
ENPP2Uncharacterized protein. (859 aa)
LOC423277Galectin. (177 aa)
LGALS3Galectin. (258 aa)
HK3Hexokinase 3. (950 aa)
CLEC19AC-type lectin domain containing 19A. (187 aa)
ADGRL2Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (1488 aa)
BLEC3C-type lectin domain-containing protein. (168 aa)
CILPCartilage intermediate layer protein. (1104 aa)
CLEC3BTetranectin. (201 aa)
GALNTL6Polypeptide N-acetylgalactosaminyltransferase. (601 aa)
PFKMUncharacterized protein. (736 aa)
FBXO44Uncharacterized protein. (304 aa)
LMAN2Lectin, mannose binding 2. (337 aa)
MAN2A2Alpha-mannosidase. (1164 aa)
Y-LEC1C-type lectin domain-containing protein. (184 aa)
CLEC17AC-type lectin domain-containing protein. (325 aa)
ENSGALP00000060823Ig-like domain-containing protein. (511 aa)
BCANBrevican. (968 aa)
FCER2C-type lectin domain-containing protein. (320 aa)
GUSBUncharacterized protein. (670 aa)
PLOD2Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2. (756 aa)
SIILUncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (506 aa)
CLC2DL5C-type lectin domain-containing protein. (237 aa)
ENSGALP00000062311C-type lectin domain-containing protein. (73 aa)
LOC101747901C-type lectin domain-containing protein. (174 aa)
ENSGALP00000063467C-type lectin domain-containing protein. (94 aa)
LOC107049847C-type lectin domain-containing protein. (204 aa)
PGR2/3C-type lectin domain-containing protein. (152 aa)
PPP1R3AProtein phosphatase 1 regulatory subunit 3A. (1088 aa)
SFTPA2Surfactant protein A. (222 aa)
LMAN2LLectin, mannose binding 2 like. (345 aa)
CRYBG3Uncharacterized protein; Belongs to the beta/gamma-crystallin family. (237 aa)
BLEC1C-type lectin-like receptor. (188 aa)
BLEC2Lectin like natural killer cell surface protein. (225 aa)
MRC2Mannose receptor C type 2. (1389 aa)
GALNT17Polypeptide N-acetylgalactosaminyltransferase. (662 aa)
CD34CD34 molecule. (385 aa)
MAN2C1Alpha-mann_mid domain-containing protein. (1029 aa)
GALNT9Polypeptide N-acetylgalactosaminyltransferase. (604 aa)
GALK1Galactokinase 1. (392 aa)
SFTPA1Lung lectin. (198 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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