STRINGSTRING
STX18 STX18 ENSGALP00000074264 ENSGALP00000074264 STX17 STX17 AXIN1 AXIN1 VAMP1 VAMP1 ANKRD46 ANKRD46 ENSGALP00000073670 ENSGALP00000073670 ENSGALP00000073564 ENSGALP00000073564 FAM172BP FAM172BP SPAG4 SPAG4 STX5 STX5 HERPUD2 HERPUD2 ENSGALP00000073136 ENSGALP00000073136 KLHDC3 KLHDC3 MAGI2 MAGI2 GAB2 GAB2 DAB2 DAB2 FRS3 FRS3 RETREG1 RETREG1 ENSGALP00000072494 ENSGALP00000072494 ATP1B3 ATP1B3 ENSGALP00000072469 ENSGALP00000072469 LOC776146 LOC776146 ENSGALP00000072121 ENSGALP00000072121 RPTOR RPTOR ANK1 ANK1 PDZK1 PDZK1 BIN3 BIN3 ANK2 ANK2 STON1 STON1 ENSGALP00000070136 ENSGALP00000070136 VPS11 VPS11 SNAP47 SNAP47 BFAR BFAR ZZEF1 ZZEF1 GOSR2 GOSR2 LOC112530163 LOC112530163 ENSGALP00000068920 ENSGALP00000068920 SPSB1 SPSB1 GRIP1 GRIP1 TSNARE1 TSNARE1 ENSGALP00000068595 ENSGALP00000068595 ENSGALP00000068436 ENSGALP00000068436 ENSGALP00000068281 ENSGALP00000068281 ENSGALP00000068168 ENSGALP00000068168 ICE1 ICE1 FBXW9 FBXW9 MAPK8IP1 MAPK8IP1 SOCS2 SOCS2 STX19 STX19 ENSGALP00000067557 ENSGALP00000067557 DOK2 DOK2 NCK1 NCK1 AP2S1 AP2S1 SLC9A3R1 SLC9A3R1 APH1A APH1A CNKSR1 CNKSR1 STX3 STX3 AP1S3 AP1S3 SLA2 SLA2 LOC770839 LOC770839 MAPK8IP2 MAPK8IP2 BICD1 BICD1 SUN1 SUN1 MAPK8IP3 MAPK8IP3 ENSGALP00000065349 ENSGALP00000065349 GNB4 GNB4 LOC107055859 LOC107055859 FAM172A FAM172A CAV2 CAV2 CNN3 CNN3 C5H14orf1 C5H14orf1 NEFL NEFL SEC22A SEC22A LOC100859551 LOC100859551 POC1A POC1A TMEM53 TMEM53 LOC428505 LOC428505 ENSGALP00000060643 ENSGALP00000060643 ENSGALP00000060289 ENSGALP00000060289 KLHDC1 KLHDC1 VTI1A VTI1A LOC101751416 LOC101751416 DOK1 DOK1 NUP153 NUP153 KSR2 KSR2 SPRYD3 SPRYD3 AP3D1 AP3D1 FRMD4B FRMD4B NOLC1 NOLC1 STX7 STX7 TLN1 TLN1 FRMD4A FRMD4A INSC INSC STX16 STX16 TCEB1 TCEB1 FAM134A FAM134A DGCR8 DGCR8 LOC101747588 LOC101747588 SEC22C SEC22C MYH9 MYH9 GAS2L1 GAS2L1 VAMP2 VAMP2 POC1B POC1B TMEM114 TMEM114 HIP1 HIP1 ANK3 ANK3 CDYL CDYL VAMP4 VAMP4 LRRK2 LRRK2 YKT6 YKT6 STX8 STX8 GATAD2A GATAD2A AP4E1 AP4E1 SPAG9 SPAG9 SEC22B SEC22B CUL2 CUL2 HIP1R HIP1R FBXW7 FBXW7 SHANK2 SHANK2 GRIP2 GRIP2 DUSP19 DUSP19 NDC1 NDC1 GAB1 GAB1 GNB3 GNB3 CUL4B CUL4B SNAP29 SNAP29 PEF1 PEF1 BTRC BTRC CNTLN CNTLN CUL1 CUL1 CNN1 CNN1 BAIAP2 BAIAP2 STX2 STX2 STX1A STX1A ENSGALP00000044404 ENSGALP00000044404 GAS6 GAS6 AP2A2 AP2A2 NAPA NAPA SPSB4 SPSB4 CAV1 CAV1 VHL VHL FEM1B FEM1B NAIF1 NAIF1 SH2D1B SH2D1B ANKRD9 ANKRD9 DOK3 DOK3 GAS2L3 GAS2L3 SUN2 SUN2 LOC426355 LOC426355 BET1 BET1 PDZD3 PDZD3 FEM1A FEM1A GNB1 GNB1 DDX20 DDX20 RAD50 RAD50 FGB FGB FSCN2 FSCN2 AMBRA1 AMBRA1 E1C5H3_CHICK E1C5H3_CHICK TRAT1 TRAT1 NUFIP1 NUFIP1 VAMP3 VAMP3 SERINC2 SERINC2 FSCN1 FSCN1 GAS2L2 GAS2L2 PRIMA1 PRIMA1 KLHDC2 KLHDC2 VAMP7 VAMP7 JUP JUP LOC419074 LOC419074 POLD3 POLD3 MZT1 MZT1 CUL4A CUL4A AP1S2 AP1S2 AKIRIN2 AKIRIN2 ANKDD1B ANKDD1B SERINC1 SERINC1 NDC80 NDC80 NAPG NAPG LOC421690 LOC421690 PEX3 PEX3 SYNE1 SYNE1 PDCD6 PDCD6 FBXO7 FBXO7 SAV1 SAV1 BANK1 BANK1 SYNE2 SYNE2 STAP1 STAP1 STX11 STX11 JCHAIN JCHAIN SYNE3 SYNE3 STON2 STON2 AKAP6 AKAP6 FRS2 FRS2 DTL DTL SH3RF1 SH3RF1 VTI1B VTI1B FGA FGA NCSTN NCSTN SNAP23 SNAP23 ANKRD9L ANKRD9L SNAP25 SNAP25 SSX2IP SSX2IP ABI1 ABI1 VPS18 VPS18 ARRDC1 ARRDC1 AP2M1 AP2M1 GAB3 GAB3 CAV3 CAV3 NAPB NAPB CIB4 CIB4 FEM1C FEM1C RAPSN RAPSN KLHDC10 KLHDC10 ANKRD60 ANKRD60 EPC1 EPC1 AKAP13 AKAP13 DET1 DET1 CRKL CRKL ZC3H18 ZC3H18 HOMER2 HOMER2 DCAF12L2 DCAF12L2 KSR1 KSR1 SLC9A3R2 SLC9A3R2 ALG14 ALG14 TCOF1 TCOF1 APPBP2 APPBP2 BICD2 BICD2 ZSWIM8 ZSWIM8 SH2B3 SH2B3 GOSR1 GOSR1 SERINC3 SERINC3 BET1L BET1L MLPH MLPH STX10 STX10 FBXO42 FBXO42 USE1 USE1 GAS2 GAS2 SARM1 SARM1 TRADD TRADD TRPC4AP TRPC4AP DAW1 DAW1 BNIP1 BNIP1 WDR59 WDR59 CRK CRK APH1B APH1B BBS4 BBS4 HERPUD1 HERPUD1 LDLRAP1 LDLRAP1 AP1G1 AP1G1 STX12 STX12 DCAF7 DCAF7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STX18Syntaxin-18_N domain-containing protein. (333 aa)
ENSGALP00000074264TIR domain-containing protein. (202 aa)
STX17t-SNARE coiled-coil homology domain-containing protein. (302 aa)
AXIN1Axin-1; Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. (841 aa)
VAMP1V-SNARE coiled-coil homology domain-containing protein. (119 aa)
ANKRD46Ankyrin repeat domain 46. (228 aa)
ENSGALP00000073670Uncharacterized protein. (184 aa)
ENSGALP00000073564Uncharacterized protein. (243 aa)
FAM172BPUncharacterized protein. (373 aa)
SPAG4SUN domain-containing protein. (314 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (344 aa)
HERPUD2HERPUD family member 2. (436 aa)
ENSGALP00000073136Uncharacterized protein. (224 aa)
KLHDC3Kelch domain containing 3. (382 aa)
MAGI2Uncharacterized protein. (1510 aa)
GAB2GRB2 associated binding protein 2. (681 aa)
DAB2DAB adaptor protein 2. (715 aa)
FRS3Fibroblast growth factor receptor substrate 3. (496 aa)
RETREG1Reticulophagy regulator 1. (365 aa)
ENSGALP00000072494Uncharacterized protein. (94 aa)
ATP1B3Sodium/potassium-transporting ATPase subunit beta-3; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known; Belongs to the X(+)/potassium ATPases subunit beta family. (289 aa)
ENSGALP00000072469SUN domain-containing protein. (280 aa)
LOC776146SUN domain-containing protein. (275 aa)
ENSGALP00000072121Uncharacterized protein. (940 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1374 aa)
ANK1Ankyrin 1. (1984 aa)
PDZK1PDZ domain containing 1. (548 aa)
BIN3Bridging integrator 3. (226 aa)
ANK2Ankyrin 2. (3970 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (823 aa)
ENSGALP00000070136Uncharacterized protein. (121 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (957 aa)
SNAP47Synaptosome associated protein 47. (461 aa)
BFARBifunctional apoptosis regulator. (449 aa)
ZZEF1Zinc finger ZZ-type and EF-hand domain containing 1. (2898 aa)
GOSR2Uncharacterized protein. (333 aa)
LOC112530163SH2 domain-containing protein. (839 aa)
ENSGALP00000068920SUN domain-containing protein 3-like isoform X1. (182 aa)
SPSB1SplA/ryanodine receptor domain and SOCS box containing 1. (273 aa)
GRIP1Glutamate receptor interacting protein 1. (1169 aa)
TSNARE1t-SNARE domain containing 1. (289 aa)
ENSGALP00000068595SUN domain-containing protein. (282 aa)
ENSGALP00000068436Uncharacterized protein. (116 aa)
ENSGALP00000068281ANK_REP_REGION domain-containing protein. (213 aa)
ENSGALP00000068168Uncharacterized protein. (144 aa)
ICE1Uncharacterized protein. (1919 aa)
FBXW9F-box domain-containing protein. (337 aa)
MAPK8IP1Mitogen-activated protein kinase 8 interacting protein 1. (678 aa)
SOCS2Uncharacterized protein. (227 aa)
STX19Syntaxin 19; Belongs to the syntaxin family. (291 aa)
ENSGALP00000067557Uncharacterized protein. (239 aa)
DOK2Docking protein 2. (641 aa)
NCK1Cytoplasmic protein. (380 aa)
AP2S1Adaptor related protein complex 2 subunit sigma 1. (279 aa)
SLC9A3R1Na(+)/H(+) exchange regulatory cofactor NHE-RF1; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Was first known to play a role in the regulation of the activity and subcellular location of SLC9A3. May enhance Wnt signaling (By similarity). (366 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (311 aa)
CNKSR1Connector enhancer of kinase suppressor of Ras 1. (811 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (462 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (209 aa)
SLA2Uncharacterized protein. (279 aa)
LOC770839SUN domain-containing protein. (306 aa)
MAPK8IP2Mitogen-activated protein kinase 8 interacting protein 2. (787 aa)
BICD1BICD cargo adaptor 1. (1149 aa)
SUN1Sad1 and UNC84 domain containing 1. (906 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1336 aa)
ENSGALP00000065349Uncharacterized protein. (159 aa)
GNB4G protein subunit beta 4. (340 aa)
LOC107055859SUN domain-containing protein. (131 aa)
FAM172ACotranscriptional regulator FAM172A homolog; May play role in the regulation of alternative splicing. May have hydrolase activity; Belongs to the FAM172 family. (416 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
CNN3Calponin; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (331 aa)
C5H14orf1Uncharacterized protein. (336 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (373 aa)
SEC22ALongin domain-containing protein; Belongs to the synaptobrevin family. (308 aa)
LOC100859551SUN domain-containing protein. (348 aa)
POC1AWD_REPEATS_REGION domain-containing protein. (507 aa)
TMEM53Uncharacterized protein. (302 aa)
LOC428505SUN domain-containing protein. (246 aa)
ENSGALP00000060643Uncharacterized protein. (116 aa)
ENSGALP00000060289Uncharacterized protein. (217 aa)
KLHDC1Kelch domain containing 1. (404 aa)
VTI1At-SNARE coiled-coil homology domain-containing protein. (224 aa)
LOC101751416SUN domain-containing protein. (331 aa)
DOK1Docking protein 1. (570 aa)
NUP153Nucleoporin 153. (1455 aa)
KSR2Kinase suppressor of ras 2. (970 aa)
SPRYD3SPRY domain containing 3. (581 aa)
AP3D1AP-3 complex subunit delta; Belongs to the adaptor complexes large subunit family. (887 aa)
FRMD4BFERM domain containing 4B. (1032 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (696 aa)
STX7t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (258 aa)
TLN1Talin-1; Probably involved in connections of major cytoskeletal structures to the plasma membrane. Talin is a high molecular weight cytoskeletal protein concentrated at regions of cell-substratum contact and, in lymphocytes, at cell-cell contacts. (2558 aa)
FRMD4AFERM domain containing 4A. (698 aa)
INSCINSC spindle orientation adaptor protein. (531 aa)
STX16t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (326 aa)
TCEB1Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
FAM134AUncharacterized protein. (559 aa)
DGCR8DGCR8 microprocessor complex subunit. (775 aa)
LOC101747588Uncharacterized protein. (753 aa)
SEC22CSEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. (304 aa)
MYH9Myosin-9; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. (1960 aa)
GAS2L1Growth arrest specific 2 like 1. (727 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (114 aa)
POC1BWD_REPEATS_REGION domain-containing protein. (468 aa)
TMEM114Transmembrane protein 114. (211 aa)
HIP1Huntingtin interacting protein 1. (1008 aa)
ANK3Uncharacterized protein. (4335 aa)
CDYLChromo domain-containing protein. (871 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
LRRK2Uncharacterized protein. (2557 aa)
YKT6Uncharacterized protein; Belongs to the synaptobrevin family. (198 aa)
STX8t-SNARE coiled-coil homology domain-containing protein. (273 aa)
GATAD2AGATA-type domain-containing protein. (599 aa)
AP4E1Adaptor related protein complex 4 subunit epsilon 1. (1144 aa)
SPAG9Sperm associated antigen 9. (1331 aa)
SEC22BVesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. (215 aa)
CUL2CULLIN_2 domain-containing protein; Belongs to the cullin family. (774 aa)
HIP1RUncharacterized protein. (977 aa)
FBXW7Uncharacterized protein. (586 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1462 aa)
GRIP2Glutamate receptor interacting protein 2. (1104 aa)
DUSP19Dual specificity phosphatase 19; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (213 aa)
NDC1NDC1 transmembrane nucleoporin. (779 aa)
GAB1GRB2 associated binding protein 1. (748 aa)
GNB3G protein subunit beta 3. (340 aa)
CUL4BCullin 4B; Belongs to the cullin family. (883 aa)
SNAP29t-SNARE coiled-coil homology domain-containing protein. (248 aa)
PEF1Penta-EF-hand domain containing 1. (223 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (793 aa)
CNTLNCentlein. (1260 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
CNN1Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. (325 aa)
BAIAP2BAI1 associated protein 2. (573 aa)
STX2t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (288 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (407 aa)
ENSGALP00000044404Uncharacterized protein. (612 aa)
GAS6Growth arrest specific 6. (667 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
NAPANSF attachment protein alpha. (313 aa)
SPSB4SplA/ryanodine receptor domain and SOCS box containing 4. (273 aa)
CAV1Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa)
VHLUncharacterized protein. (161 aa)
FEM1BProtein fem-1 homolog B; Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis (By similarity); Belongs to the fem-1 family. (627 aa)
NAIF1Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family. (328 aa)
SH2D1BSH2 domain-containing protein. (134 aa)
ANKRD9Ankyrin repeat domain 9. (292 aa)
DOK3Docking protein 3; DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. Plays a role as negative regulator of the mobilization of calcium ions and of calcium signaling. (426 aa)
GAS2L3Uncharacterized protein. (726 aa)
SUN2Sad1 and UNC84 domain containing 2. (601 aa)
LOC426355Myb_DNA-bind_5 domain-containing protein. (589 aa)
BET1t-SNARE coiled-coil homology domain-containing protein. (115 aa)
PDZD3PDZ domain containing 3. (531 aa)
FEM1AFem-1 homolog A. (765 aa)
GNB1WD_REPEATS_REGION domain-containing protein. (340 aa)
DDX20DEAD-box helicase 20; Belongs to the DEAD box helicase family. (767 aa)
RAD50Zinc-hook domain-containing protein. (1313 aa)
FGBFibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. (488 aa)
FSCN2Fascin. (491 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (872 aa)
E1C5H3_CHICKSUN domain-containing protein. (197 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (175 aa)
NUFIP1C2H2-type domain-containing protein. (527 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (104 aa)
SERINC2Uncharacterized protein. (514 aa)
FSCN1Fascin. (490 aa)
GAS2L2Calponin-homology (CH) domain-containing protein. (207 aa)
PRIMA1Proline rich membrane anchor 1. (157 aa)
KLHDC2Uncharacterized protein. (407 aa)
VAMP7Vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for focal exocytosis of late endocytic vesicles during phagosome formation (By similarity); Belongs to the synaptobrevin family. (220 aa)
JUPPlakoglobin. (747 aa)
LOC419074Uncharacterized protein. (765 aa)
POLD3DNA polymerase delta subunit 3; Accessory component of both the DNA polymerase delta complex and the DNA polymerase zeta complex. As a component of the trimeric and tetrameric DNA polymerase delta complexes (Pol-delta3 and Pol-delta4, respectively), plays a role in high fidelity genome replication, including in lagging strand synthesis, and repair. Required for optimal Pol-delta activity. Stabilizes the Pol-delta complex and plays a major role in Pol-delta stimulation by PCNA. Pol-delta3 and Pol-delta4 are characterized by the absence or the presence of POLD4. They exhibit differences [...] (467 aa)
MZT1Uncharacterized protein. (89 aa)
CUL4ACullin 4A; Belongs to the cullin family. (767 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (157 aa)
AKIRIN2Akirin. (191 aa)
ANKDD1BAnkyrin repeat and death domain containing 1B. (543 aa)
SERINC1Uncharacterized protein. (461 aa)
NDC80Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (640 aa)
NAPGNSF attachment protein gamma. (314 aa)
LOC421690Uncharacterized protein. (574 aa)
PEX3Uncharacterized protein. (369 aa)
SYNE1Uncharacterized protein. (8377 aa)
PDCD6Programmed cell death 6. (178 aa)
FBXO7F-box domain-containing protein. (526 aa)
SAV1Salvador family WW domain containing protein 1. (385 aa)
BANK1B cell scaffold protein with ankyrin repeats 1. (730 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6982 aa)
STAP1Signal transducing adaptor family member 1. (293 aa)
STX11Syntaxin 11. (288 aa)
JCHAINUncharacterized protein. (158 aa)
SYNE3Spectrin repeat containing nuclear envelope family member 3. (955 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (887 aa)
AKAP6A-kinase anchoring protein 6. (2342 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
DTLDenticleless protein homolog; Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1, CDKN1A/p21(CIP1), KMT5A and SDE2. CDT1 degradation in response to DNA damage is necessary to ensure proper cell cycle regulation of DNA replication. CDKN1A/p21(CIP1) degradation during S phase or following UV irradiation is essential to control replication licensing. [...] (720 aa)
SH3RF1SH3 domain containing ring finger 1. (872 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
FGAFibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. (741 aa)
NCSTNNcstrn_small domain-containing protein. (717 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (209 aa)
ANKRD9LANK_REP_REGION domain-containing protein. (293 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa)
SSX2IPUncharacterized protein. (560 aa)
ABI1Uncharacterized protein. (507 aa)
VPS18Pep3_Vps18 domain-containing protein. (974 aa)
ARRDC1Arrestin_C domain-containing protein. (421 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide- containing lipids (By similarity). (489 aa)
GAB3GRB2 associated binding protein 3. (569 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
NAPBUncharacterized protein. (296 aa)
CIB4Uncharacterized protein. (190 aa)
FEM1CFem-1 homolog C. (617 aa)
RAPSN43 kDa receptor-associated protein of the synapse; Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin (By similarity). Belongs to the RAPsyn family. (412 aa)
KLHDC10Kelch domain containing 10. (409 aa)
ANKRD60ANK_REP_REGION domain-containing protein. (151 aa)
EPC1Enhancer of polycomb homolog. (814 aa)
AKAP13Uncharacterized protein. (1341 aa)
DET1Uncharacterized protein. (551 aa)
CRKLCRK like proto-oncogene, adaptor protein. (193 aa)
ZC3H18Zinc finger CCCH-type containing 18. (902 aa)
HOMER2Homer scaffold protein 2. (356 aa)
DCAF12L2DDB1- and CUL4-associated factor 12; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex. (427 aa)
KSR1Protein kinase domain-containing protein. (112 aa)
SLC9A3R2Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. (354 aa)
ALG14Uncharacterized protein. (219 aa)
TCOF1LisH domain-containing protein. (974 aa)
APPBP2TPR_REGION domain-containing protein. (586 aa)
BICD2BICD cargo adaptor 2. (829 aa)
ZSWIM8SWIM-type domain-containing protein. (1833 aa)
SH2B3SH2B adaptor protein 3. (539 aa)
GOSR1Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (243 aa)
SERINC3Uncharacterized protein. (472 aa)
BET1Lt-SNARE coiled-coil homology domain-containing protein. (111 aa)
MLPHRabBD domain-containing protein. (748 aa)
STX10Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. (254 aa)
FBXO42F-box protein 42. (764 aa)
USE1Uncharacterized protein. (259 aa)
GAS2Uncharacterized protein. (314 aa)
SARM1Uncharacterized protein. (454 aa)
TRADDTNFRSF1A associated via death domain. (461 aa)
TRPC4APUncharacterized protein. (771 aa)
DAW1Dynein assembly factor with WD repeats 1. (415 aa)
BNIP1BCL2 interacting protein 1. (230 aa)
WDR59GATOR complex protein WDR59; As a component of the GATOR complex may function in the amino acid-sensing branch of the TORC1 signaling pathway. (973 aa)
CRKAdapter molecule crk; May mediate attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. May regulate the EFNA5-EPHA3 signaling (By similarity). (305 aa)
APH1BUncharacterized protein. (256 aa)
BBS4TPR_REGION domain-containing protein. (532 aa)
HERPUD1Homocysteine inducible ER protein with ubiquitin like domain 1. (401 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (144 aa)
AP1G1AP-1 complex subunit gamma. (821 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (272 aa)
DCAF7WD_REPEATS_REGION domain-containing protein. (460 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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