STRINGSTRING
LOC770026 LOC770026 SYT11 SYT11 GFER GFER SEMA6C SEMA6C LPCAT3 LPCAT3 METTL3 METTL3 LOC420294 LOC420294 NDFIP1 NDFIP1 BBS2 BBS2 TNFRSF1B TNFRSF1B PTPRS PTPRS AJAP1 AJAP1 CARTPT CARTPT SEMA3B SEMA3B TNFRSF8 TNFRSF8 C26H6orf106 C26H6orf106 ITCH ITCH SEMA5B SEMA5B GRN GRN APOH APOH AOAH AOAH PADI2 PADI2 LOC100859819 LOC100859819 RGMA RGMA MUL1 MUL1 PPARA PPARA DPP4 DPP4 STAT2 STAT2 YTHDF2 YTHDF2 NRXN1 NRXN1 CXCL13L3 CXCL13L3 TKFC TKFC PTPRD PTPRD NLRC5 NLRC5 NELL1 NELL1 SEMA3E SEMA3E ATG5 ATG5 C5 C5 HGF HGF TNFRSF1A TNFRSF1A OTOP1 OTOP1 FAM105A FAM105A CASK CASK CLASP1 CLASP1 UBASH3B UBASH3B SEC14L1 SEC14L1 TNFAIP3 TNFAIP3 CCN3 CCN3 TRAFD1 TRAFD1 BANF1 BANF1 SLIT2 SLIT2 SEMA3F SEMA3F SIRT2 SIRT2 NLRC3 NLRC3 ADTRP ADTRP YTHDF3 YTHDF3 LOC428593 LOC428593 ISL1 ISL1 FFAR4 FFAR4 SOCS3 SOCS3 SEMA3A SEMA3A C5orf30 C5orf30 CX3CL1 CX3CL1 SEMA4G SEMA4G SELENOS SELENOS GHSR GHSR CACTIN CACTIN NUCB2 NUCB2 NELL2 NELL2 SEMA4D SEMA4D GPR18 GPR18 UFD1L UFD1L PLA2G10 PLA2G10 GCG GCG NR1D2 NR1D2 PLA2G10L PLA2G10L CD200L CD200L CD9 CD9 PSMB4 PSMB4 CPB2 CPB2 ACOD1 ACOD1 PBK PBK FNDC4 FNDC4 NT5E NT5E GRIN3A GRIN3A PROS1 PROS1 CD200 CD200 DRD3 DRD3 RIOK3 RIOK3 LYAR LYAR ASH1L ASH1L PLA2G5 PLA2G5 TTLL12 TTLL12 PTPN2 PTPN2 MVK MVK CNOT7 CNOT7 SPX SPX IL20RB IL20RB LRFN5 LRFN5 TNFAIP6 TNFAIP6 PDGFB PDGFB STAP1 STAP1 NR1H4 NR1H4 MMRN1 MMRN1 CXCL13L2 CXCL13L2 SOCS5 SOCS5 CYLD CYLD NENF NENF THBS1 THBS1 ARG2 ARG2 DUSP10 DUSP10 INPP5F INPP5F SUSD4 SUSD4 FGG FGG MKKS MKKS CST7 CST7 HRG HRG GHRL GHRL F2 F2 FGL2 FGL2 SEMA4B SEMA4B DRD2 DRD2 RTN4R RTN4R IRG1L IRG1L SERPING1 SERPING1 APOA1 APOA1 TSPAN6 TSPAN6 NLRX1 NLRX1 SEMA3D SEMA3D RYK RYK ABCC8 ABCC8 KREMEN1 KREMEN1 ADIPOQ ADIPOQ WFDC1 WFDC1 MYOZ1 MYOZ1 SERPINE2 SERPINE2 MKRN2 MKRN2 SH2B3 SH2B3 SEMA3G SEMA3G VPS35 VPS35 PLG PLG TRAF3IP1 TRAF3IP1 GPER1 GPER1 DHX58 DHX58 SEMA3DL SEMA3DL HOMER3 HOMER3 ATG12 ATG12 SEMA6A SEMA6A C1QTNF12 C1QTNF12 BBS4 BBS4 PROC PROC LRIG2 LRIG2 C1QBP C1QBP SEMA7A SEMA7A IL12B IL12B WNT3 WNT3 CD34 CD34 SAMHD1 SAMHD1 SMPDL3B SMPDL3B GPATCH3 GPATCH3 IL10 IL10 ENSGALP00000074158 ENSGALP00000074158 TFPI TFPI PPARD PPARD RIN3 RIN3 CLDN19 CLDN19 UCN UCN TAFA3 TAFA3 RB1 RB1 PHLDB2 PHLDB2 NR1D1 NR1D1 GPR17 GPR17 LOC101750889 LOC101750889 GATA3 GATA3 CLASP2 CLASP2 ADAR ADAR PPARG PPARG OTULIN OTULIN MMP28 MMP28 SEMA6B SEMA6B SEMA5A SEMA5A ENSGALP00000066581 ENSGALP00000066581 SEMA4C SEMA4C SEMA3C SEMA3C SEMA6D SEMA6D LOC112530215 LOC112530215 PTGER4 PTGER4 ANGPT2 ANGPT2 CXCL13 CXCL13 VSIG4 VSIG4 RNF26 RNF26 NMI NMI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC770026Uncharacterized protein. (305 aa)
SYT11Synaptotagmin 11. (432 aa)
GFERSulfhydryl oxidase. (191 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (837 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (501 aa)
METTL3Methyltransferase like 3; Belongs to the MT-A70-like family. (548 aa)
LOC420294Uncharacterized protein; Belongs to the peptidase C19 family. (787 aa)
NDFIP1Nedd4 family interacting protein 1. (213 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
TNFRSF1BUncharacterized protein. (462 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (By similarity). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for norm [...] (1924 aa)
AJAP1Adherens junctions associated protein 1. (266 aa)
CARTPTCART prepropeptide. (111 aa)
SEMA3BSemaphorin 3B. (608 aa)
TNFRSF8TNFR-Cys domain-containing protein. (467 aa)
C26H6orf106Protein ILRUN; May have a roles as negative regulator of innate antiviral response. (291 aa)
ITCHE3 ubiquitin-protein ligase. (878 aa)
SEMA5BSemaphorin 5B. (1150 aa)
GRNUncharacterized protein. (287 aa)
APOHUncharacterized protein. (374 aa)
AOAHAcyloxyacyl hydrolase. (639 aa)
PADI2Peptidylarginine deiminase type II. (663 aa)
LOC100859819CARTL. (113 aa)
RGMARepulsive guidance molecule A; Acts as an axon-specific repulsive guidance molecule in the retinotectal system. Repulsive for a subset of axons of the temporal half of the retina. Provides thus positional information for the temporal axons invading the optic tectum in the stratum opticum. (436 aa)
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (252 aa)
PPARAUncharacterized protein. (468 aa)
DPP4Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa)
STAT2Signal transducer and activator of transcription. (961 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (645 aa)
NRXN1Neurexin-1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. (1503 aa)
CXCL13L3Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (103 aa)
TKFCTriokinase and FMN cyclase. (576 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1963 aa)
NLRC5NACHT domain-containing protein. (1862 aa)
NELL1Neural EGFL like 1. (761 aa)
SEMA3ESemaphorin-3E; Plays an important role in signaling via the cell surface receptor PLXND1. Mediates reorganization of the actin cytoskeleton, leading to the retraction of cell projections. Promotes focal adhesion disassembly and inhibits adhesion of endothelial cells to the extracellular matrix. Regulates angiogenesis. Can down-regulate sprouting angiogenesis. Required for normal vascular patterning during embryogenesis. Induces the collapse and paralysis of neuronal growth cones. Plays an important role in ensuring the specificity of synapse formation (By similarity); Belongs to the se [...] (779 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
C5Complement C5. (1758 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa)
TNFRSF1AUncharacterized protein. (427 aa)
OTOP1Otopetrin 1. (609 aa)
FAM105AUncharacterized protein. (411 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (944 aa)
CLASP1Cytoplasmic linker associated protein 1. (1499 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (651 aa)
SEC14L1SEC14 like lipid binding 1. (715 aa)
TNFAIP3TNF alpha induced protein 3. (806 aa)
CCN3CCN family member 3; Immediate-early protein likely to play a role in cell growth regulation. Its overexpression is associated with tumorigenesis and expression of a N-terminal-truncated version of CCN3 gene in chicken embryonic fibroblasts (CEF) is sufficient to induce the transformation of CEF in vitro. (351 aa)
TRAFD1Uncharacterized protein. (582 aa)
BANF1Barrier to autointegration factor 1. (90 aa)
SLIT2Uncharacterized protein. (1533 aa)
SEMA3FSema domain-containing protein; Belongs to the semaphorin family. (838 aa)
SIRT2Deacetylase sirtuin-type domain-containing protein. (485 aa)
NLRC3NLR family CARD domain containing 3. (1095 aa)
ADTRPAndrogen dependent TFPI regulating protein. (233 aa)
YTHDF3YTH domain-containing protein. (593 aa)
LOC428593Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (818 aa)
ISL1Insulin gene enhancer protein ISL-1; Acts as a transcriptional regulator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA- 3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to insulin gene enhancer sequences (By similarity). Defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with LHX1, LHX3 and ISL2. Binds to insulin gene enhancer sequences (By similarity). Essential for heart d [...] (349 aa)
FFAR4Free fatty acid receptor 4. (349 aa)
SOCS3Suppressor of cytokine signaling 3; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS3 is involved in negative regulation of cytokines that signal through the JAK/STAT pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin and leptin receptors (By similarity). Binding to JAK2 inhibits its kinase activity (By similarity). Regulates onset and maintenance of allergic responses mediated by T-helper type 2 cells (By similarity). Regulates IL-6 [...] (209 aa)
SEMA3ASemaphorin-3A; Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to neuropilin; Belongs to the semaphorin family. (815 aa)
C5orf30Chromosome 5 open reading frame 30. (207 aa)
CX3CL1SCY domain-containing protein. (496 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (841 aa)
SELENOSUncharacterized protein. (207 aa)
GHSRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (561 aa)
CACTINCactin, spliceosome C complex subunit. (731 aa)
NUCB2Uncharacterized protein. (455 aa)
NELL2Protein NEL. (816 aa)
SEMA4DSemaphorin-4D; Cell surface receptor for PLXNB1 that plays an important role in cell-cell signaling (By similarity). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (By similarity). (855 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (320 aa)
UFD1LUbiquitin fusion-degradation 1-like protein. (307 aa)
PLA2G10Phospholipase A(2). (155 aa)
GCGGlicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. (206 aa)
NR1D2Uncharacterized protein. (587 aa)
PLA2G10LPhospholipase A(2). (158 aa)
CD200LIG domain-containing protein. (349 aa)
CD9Tetraspanin. (224 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (258 aa)
CPB2Carboxypeptidase B2. (421 aa)
ACOD1Uncharacterized protein. (478 aa)
PBKProtein kinase domain-containing protein. (322 aa)
FNDC4Fibronectin type-III domain-containing protein. (206 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (561 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (1126 aa)
PROS1Protein S. (702 aa)
CD200Uncharacterized protein. (254 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (425 aa)
RIOK3Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (516 aa)
LYARLy1 antibody reactive. (364 aa)
ASH1LASH1 like histone lysine methyltransferase. (3026 aa)
PLA2G5Phospholipase A(2). (158 aa)
TTLL12Uncharacterized protein. (627 aa)
PTPN2Uncharacterized protein. (597 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (397 aa)
CNOT7CCR4-NOT transcription complex subunit 7; Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA- mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence [...] (285 aa)
SPXSpexin hormone. (116 aa)
IL20RBInterleukin 20 receptor subunit beta. (312 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (774 aa)
TNFAIP6Tumor necrosis factor-inducible protein 6. (275 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (251 aa)
STAP1Signal transducing adaptor family member 1. (293 aa)
NR1H4Farnesoid X receptor. (473 aa)
MMRN1Multimerin 1. (1192 aa)
CXCL13L2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (100 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (941 aa)
NENFNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (164 aa)
THBS1Uncharacterized protein. (1175 aa)
ARG2Arginase. (356 aa)
DUSP10Uncharacterized protein. (478 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1126 aa)
SUSD4Sushi domain containing 4. (330 aa)
FGGFibrinogen C-terminal domain-containing protein. (438 aa)
MKKSUncharacterized protein. (570 aa)
CST7Cystatin domain-containing protein. (147 aa)
HRGUncharacterized protein. (1078 aa)
GHRLPreproghrelin. (116 aa)
F2Uncharacterized protein; Belongs to the peptidase S1 family. (644 aa)
FGL2Fibrinogen C-terminal domain-containing protein. (439 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (861 aa)
DRD2Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa)
RTN4RReticulon 4 receptor. (483 aa)
IRG1LUncharacterized protein. (463 aa)
SERPING1Calponin-homology (CH) domain-containing protein; Belongs to the serpin family. (776 aa)
APOA1Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa)
TSPAN6Tetraspanin. (252 aa)
NLRX1NLR family member X1. (990 aa)
SEMA3DSemaphorin-3D; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (761 aa)
RYKReceptor like tyrosine kinase. (481 aa)
ABCC8ATP binding cassette subfamily C member 8. (1595 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (450 aa)
ADIPOQC1q domain-containing protein. (244 aa)
WFDC1WAP four-disulfide core domain protein 1; Has growth inhibitory activity. (222 aa)
MYOZ1Myozenin 1. (278 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (442 aa)
MKRN2Uncharacterized protein. (417 aa)
SH2B3SH2B adaptor protein 3. (539 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (761 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (799 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (802 aa)
TRAF3IP1TRAF3 interacting protein 1. (665 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
DHX58Uncharacterized protein. (674 aa)
SEMA3DLIg-like domain-containing protein. (165 aa)
HOMER3Sema domain-containing protein; Belongs to the semaphorin family. (763 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (146 aa)
SEMA6ASemaphorin-6A isoform4; Belongs to the semaphorin family. (1044 aa)
C1QTNF12C1q and TNF related 12. (320 aa)
BBS4TPR_REGION domain-containing protein. (532 aa)
PROCUncharacterized protein. (433 aa)
LRIG2Leucine rich repeats and immunoglobulin like domains 2. (1055 aa)
C1QBPComplement C1q binding protein. (214 aa)
SEMA7ASema domain-containing protein; Belongs to the semaphorin family. (636 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
CD34CD34 molecule. (385 aa)
SAMHD1Deoxynucleoside triphosphate triphosphohydrolase SAMHD1; Protein that acts both as a host restriction factor involved in defense response to virus and as a regulator of DNA end resection at stalled replication forks. Has deoxynucleoside triphosphate (dNTPase) activity, which is required to restrict infection by viruses: dNTPase activity reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur, blocking early-stage virus replication in dendritic and other myeloid cells. Functions during S phase at stalled DNA replication forks to promote the resection [...] (614 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (459 aa)
GPATCH3G-patch domain-containing protein. (493 aa)
IL10Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (175 aa)
ENSGALP00000074158LAM_G_DOMAIN domain-containing protein. (326 aa)
TFPITissue factor pathway inhibitor. (311 aa)
PPARDUncharacterized protein. (545 aa)
RIN3Ras and Rab interactor 3. (983 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (225 aa)
UCNUrocortin. (100 aa)
TAFA3TAFA chemokine like family member 3. (136 aa)
RB1Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] (984 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1349 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (678 aa)
GPR17G_PROTEIN_RECEP_F1_2 domain-containing protein. (104 aa)
LOC101750889LRRCT domain-containing protein. (714 aa)
GATA3GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa)
CLASP2Uncharacterized protein. (1506 aa)
ADARRNA-specific Adenosine deaminase Transcript variant M. (1153 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (498 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (319 aa)
MMP28Matrix metallopeptidase 28. (460 aa)
SEMA6BSema domain-containing protein; Belongs to the semaphorin family. (870 aa)
SEMA5ASemaphorin 5A. (1076 aa)
ENSGALP00000066581Uncharacterized protein. (532 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (1080 aa)
SEMA3CSemaphorin-3C; Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin; Belongs to the semaphorin family. (751 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1088 aa)
LOC112530215Sema domain-containing protein; Belongs to the semaphorin family. (606 aa)
PTGER4Prostaglandin E2 receptor subtype 4; Belongs to the G-protein coupled receptor 1 family. (475 aa)
ANGPT2Angiopoietin-2A. (493 aa)
CXCL13Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
VSIG4V-set and immunoglobulin domain containing 4. (389 aa)
RNF26Ring finger protein 26. (469 aa)
NMIN-myc and STAT interactor. (381 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (18%) [HD]