21 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107050658	Free fatty acid receptor 2-like. (367 aa)
	ADIPOQ	C1q domain-containing protein. (244 aa)
	F3	Coagulation factor III, tissue factor. (283 aa)
	FADD	Fas associated via death domain. (195 aa)
	TLR5	TLR5; Belongs to the Toll-like receptor family. (861 aa)
	TLR3	Toll-like receptor 3; Belongs to the Toll-like receptor family. (896 aa)
	RIPK1	Uncharacterized protein. (682 aa)
	DDIT3	C/EBP-like protein. (155 aa)
	IL1B	Interleukin-1; Belongs to the IL-1 family. (267 aa)
	TLR7	Toll-like receptor 7; Belongs to the Toll-like receptor family. (1059 aa)
	CD14	Uncharacterized protein. (465 aa)
	NOD1	Uncharacterized protein. (951 aa)
	NOS2	Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. NO may serve as both a paracrine and autocrine signal for modulating osteoclast bone resorption. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2 (By similarity); Belongs to the NOS family. (1136 aa)
	TIRAP	TIR domain-containing protein. (231 aa)
	CD74	Invariant chain isoform p41. (286 aa)
	CD244	Ig-like domain-containing protein. (383 aa)
	LOC396098	Uncharacterized protein. (335 aa)
	IL6	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa)
	CD2	Uncharacterized protein. (301 aa)
	FFAR2L	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa)
	ENSGALP00000069003	Ig-like domain-containing protein. (306 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	IL1B	ENSGALP00000008899	ENSGALP00000050171	C1q domain-containing protein.	Interleukin-1; Belongs to the IL-1 family.	0.744
ADIPOQ	IL6	ENSGALP00000008899	ENSGALP00000068117	C1q domain-containing protein.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.866
CD14	CD2	ENSGALP00000052840	ENSGALP00000068151	Uncharacterized protein.	Uncharacterized protein.	0.533
CD14	FADD	ENSGALP00000052840	ENSGALP00000012326	Uncharacterized protein.	Fas associated via death domain.	0.546
CD14	IL1B	ENSGALP00000052840	ENSGALP00000050171	Uncharacterized protein.	Interleukin-1; Belongs to the IL-1 family.	0.659
CD14	IL6	ENSGALP00000052840	ENSGALP00000068117	Uncharacterized protein.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.625
CD14	RIPK1	ENSGALP00000052840	ENSGALP00000036418	Uncharacterized protein.	Uncharacterized protein.	0.546
CD2	CD14	ENSGALP00000068151	ENSGALP00000052840	Uncharacterized protein.	Uncharacterized protein.	0.533
CD74	IL1B	ENSGALP00000063230	ENSGALP00000050171	Invariant chain isoform p41.	Interleukin-1; Belongs to the IL-1 family.	0.459
CD74	IL6	ENSGALP00000063230	ENSGALP00000068117	Invariant chain isoform p41.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.436
CD74	TLR7	ENSGALP00000063230	ENSGALP00000070844	Invariant chain isoform p41.	Toll-like receptor 7; Belongs to the Toll-like receptor family.	0.421
F3	IL1B	ENSGALP00000009003	ENSGALP00000050171	Coagulation factor III, tissue factor.	Interleukin-1; Belongs to the IL-1 family.	0.557
F3	IL6	ENSGALP00000009003	ENSGALP00000068117	Coagulation factor III, tissue factor.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.646
FADD	CD14	ENSGALP00000012326	ENSGALP00000052840	Fas associated via death domain.	Uncharacterized protein.	0.546
FADD	IL1B	ENSGALP00000012326	ENSGALP00000050171	Fas associated via death domain.	Interleukin-1; Belongs to the IL-1 family.	0.462
FADD	IL6	ENSGALP00000012326	ENSGALP00000068117	Fas associated via death domain.	Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily.	0.419
FADD	RIPK1	ENSGALP00000012326	ENSGALP00000036418	Fas associated via death domain.	Uncharacterized protein.	0.999
FADD	TLR3	ENSGALP00000012326	ENSGALP00000021914	Fas associated via death domain.	Toll-like receptor 3; Belongs to the Toll-like receptor family.	0.542
IL1B	ADIPOQ	ENSGALP00000050171	ENSGALP00000008899	Interleukin-1; Belongs to the IL-1 family.	C1q domain-containing protein.	0.744
IL1B	CD14	ENSGALP00000050171	ENSGALP00000052840	Interleukin-1; Belongs to the IL-1 family.	Uncharacterized protein.	0.659