(20 nodes) Protein localization to cell surface network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

textmining

co-expression

protein homology

Your Input:
	UNC50	Uncharacterized protein. (259 aa)
	JAM3	Junctional adhesion molecule 3. (458 aa)
	LRIG2	Leucine rich repeats and immunoglobulin like domains 2. (1055 aa)
	WNT11	Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters. (354 aa)
	SMURF1	E3 ubiquitin-protein ligase. (744 aa)
	VCL	Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family. (1135 aa)
	RIC3	RIC3 acetylcholine receptor chaperone. (394 aa)
	GGA2	Uncharacterized protein. (490 aa)
	ASTN2	Astrotactin 2. (1293 aa)
	GGA3	Uncharacterized protein. (754 aa)
	PIGK	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (393 aa)
	WNT11B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (386 aa)
	ARF6	ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity). (175 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	CTNNB1	Uncharacterized protein. (781 aa)
	PTPRK	Protein tyrosine phosphatase receptor type K. (1445 aa)
	GGA1	Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (665 aa)
	EMP2	Epithelial membrane protein 2. (167 aa)
	PIGU	Phosphatidylinositol glycan anchor biosynthesis class U. (444 aa)
	ENSGALP00000072815	VHS domain-containing protein. (90 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARF6	GGA1	ENSGALP00000041604	ENSGALP00000055669	ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.400
ARF6	GGA3	ENSGALP00000041604	ENSGALP00000012961	ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).	Uncharacterized protein.	0.914
CTNNB1	VCL	ENSGALP00000045406	ENSGALP00000008131	Uncharacterized protein.	Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family.	0.745
ENSGALP00000072815	GGA2	ENSGALP00000072815	ENSGALP00000009899	VHS domain-containing protein.	Uncharacterized protein.	0.896
FGF7	WNT11	ENSGALP00000042868	ENSGALP00000001229	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters.	0.497
GGA1	ARF6	ENSGALP00000055669	ENSGALP00000041604	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).	0.400
GGA1	GGA2	ENSGALP00000055669	ENSGALP00000009899	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Uncharacterized protein.	0.911
GGA1	GGA3	ENSGALP00000055669	ENSGALP00000012961	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	Uncharacterized protein.	0.930
GGA2	ENSGALP00000072815	ENSGALP00000009899	ENSGALP00000072815	Uncharacterized protein.	VHS domain-containing protein.	0.896
GGA2	GGA1	ENSGALP00000009899	ENSGALP00000055669	Uncharacterized protein.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.911
GGA2	GGA3	ENSGALP00000009899	ENSGALP00000012961	Uncharacterized protein.	Uncharacterized protein.	0.939
GGA3	ARF6	ENSGALP00000012961	ENSGALP00000041604	Uncharacterized protein.	ADP-ribosylation factor 6; GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May contribute to the regulation of dendritic branching, filopodia extension and dendritic spine development (By similarity).	0.914
GGA3	GGA1	ENSGALP00000012961	ENSGALP00000055669	Uncharacterized protein.	Golgi associated, gamma adaptin ear containing, ARF binding protein 1.	0.930
GGA3	GGA2	ENSGALP00000012961	ENSGALP00000009899	Uncharacterized protein.	Uncharacterized protein.	0.939
PIGK	PIGU	ENSGALP00000014651	ENSGALP00000067931	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	Phosphatidylinositol glycan anchor biosynthesis class U.	0.996
PIGU	PIGK	ENSGALP00000067931	ENSGALP00000014651	Phosphatidylinositol glycan anchor biosynthesis class U.	GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.	0.996
RIC3	UNC50	ENSGALP00000009586	ENSGALP00000056545	RIC3 acetylcholine receptor chaperone.	Uncharacterized protein.	0.981
UNC50	RIC3	ENSGALP00000056545	ENSGALP00000009586	Uncharacterized protein.	RIC3 acetylcholine receptor chaperone.	0.981
VCL	CTNNB1	ENSGALP00000008131	ENSGALP00000045406	Vinculin; Actin filament (F-actin)-binding protein involved in cell- matrix adhesion and cell-cell adhesion. Regulates cell-surface E- cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion; Belongs to the vinculin/alpha-catenin family.	Uncharacterized protein.	0.745
WNT11	FGF7	ENSGALP00000001229	ENSGALP00000042868	Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.497