(12 nodes) Positive regulation of insulin secretion involved in cellular response to glucose stimulus network (Gallus gallus)

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Your Input:
	RFX6	Regulatory factor X6. (916 aa)
	C1QTNF12	C1q and TNF related 12. (320 aa)
	SRI	Uncharacterized protein. (297 aa)
	NR1H4	Farnesoid X receptor. (473 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (856 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa)
	PDX1	Homeobox domain-containing protein. (259 aa)
	C2CD2L	SMP_C2CD2L domain-containing protein. (707 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1485 aa)
	GCG	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. (206 aa)
	MPC2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (133 aa)
	PLA2G6	Uncharacterized protein. (796 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C1QTNF12	RFX6	ENSGALP00000002872	ENSGALP00000024015	C1q and TNF related 12.	Regulatory factor X6.	0.478
GCG	NR1H4	ENSGALP00000032494	ENSGALP00000018906	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.	Farnesoid X receptor.	0.600
NR1H4	GCG	ENSGALP00000018906	ENSGALP00000032494	Farnesoid X receptor.	Glicentin-related polypeptide; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.	0.600
RFX6	C1QTNF12	ENSGALP00000024015	ENSGALP00000002872	Regulatory factor X6.	C1q and TNF related 12.	0.478