Your Input: | |
| | LOC771804 | Ig-like domain-containing protein. (241 aa) |
| | ENSGALP00000061280 | Ig-like domain-containing protein. (218 aa) |
| | LOC107049200 | Ig-like domain-containing protein. (155 aa) |
| | LOC100858506 | Interferon alpha. (193 aa) |
| | ENSGALP00000060244 | Ig-like domain-containing protein. (234 aa) |
| | CD8A-2 | Ig-like domain-containing protein. (235 aa) |
| | RAG2 | V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (535 aa) |
| | TCD8AL4 | Ig-like domain-containing protein. (212 aa) |
| | SASH3 | Uncharacterized protein. (382 aa) |
| | HLX | H2.0 like homeobox. (431 aa) |
| | TESPA1 | KRAP_IP3R_bind domain-containing protein. (600 aa) |
| | IL6R | Uncharacterized protein. (445 aa) |
| | BCL11B | BAF chromatin remodeling complex subunit BCL11B. (884 aa) |
| | PCASP2 | Uncharacterized protein. (741 aa) |
| | CHD7 | Chromodomain-helicase-DNA-binding protein 7; Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production (By similarity). (3009 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break b [...] (1041 aa) |
| | PTPRC | Uncharacterized protein. (1237 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (878 aa) |
| | SRF | Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa) |
| | MYH9 | Myosin-9; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. (1960 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (384 aa) |
| | IL4R | Fibronectin type-III domain-containing protein. (996 aa) |
| | PCASP3 | Uncharacterized protein. (632 aa) |
| | DPP4 | Uncharacterized protein; Belongs to the peptidase S9B family. (760 aa) |
| | ABL2 | Tyrosine-protein kinase. (1159 aa) |
| | IL7 | Interleukin-7. (146 aa) |
| | PRR7 | Proline rich 7, synaptic. (231 aa) |
| | KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. Activated KIT also transmits signals via [...] (960 aa) |
| | FZD7 | Frizzled-7; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (567 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa) |
| | FKBP1B | Peptidylprolyl isomerase. (108 aa) |
| | RORC | RAR related orphan receptor C. (461 aa) |
| | NKX2-6 | Homeobox domain-containing protein. (193 aa) |
| | NKX2-3 | Homeobox domain-containing protein. (328 aa) |
| | CCR7 | C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | LOC100857714 | Uncharacterized protein. (383 aa) |
| | ENSGALP00000048186 | Uncharacterized protein. (528 aa) |
| | CHD9 | Chromodomain helicase DNA binding protein 9. (2820 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (574 aa) |
| | MALT1 | MALT1 paracaspase. (816 aa) |
| | THEMIS | Thymocyte selection associated. (776 aa) |
| | SP3 | Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription (By similarity). Required for activation of SPARC transcription; Belongs to the Sp1 C2H2-type zinc-finger protein family. (771 aa) |
| | LOC112532337 | Ig-like domain-containing protein. (215 aa) |
| | MSN | Moesin. (580 aa) |
| | CTNNB1 | Uncharacterized protein. (781 aa) |
| | LFNG | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning. (363 aa) |
| | NLRC3 | NLR family CARD domain containing 3. (1095 aa) |
| | CCL19-2 | SCY domain-containing protein. (99 aa) |
| | FKBP1A | Peptidylprolyl isomerase. (108 aa) |
| | EOMES | T-box_assoc domain-containing protein. (661 aa) |
| | PELI3 | Uncharacterized protein. (418 aa) |
| | IFNW1 | Interferon type B; Has antiviral activities; Belongs to the alpha/beta interferon family. (203 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (711 aa) |
| | GPR18 | G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (320 aa) |
| | TREM-B2 | Uncharacterized protein. (601 aa) |
| | LEPR | Uncharacterized protein. (1148 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) |
| | TSTD1 | Uncharacterized protein. (358 aa) |
| | GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (371 aa) |
| | TNFSF13B | TNF family B cell activation factor; Belongs to the tumor necrosis factor family. (288 aa) |
| | RSAD2 | Viperin. (354 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (797 aa) |
| | PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) |
| | LCK | Proto-oncogene tyrosine-protein kinase LCK; Tyrosine kinase that plays an essential role for the selection and maturation of developing T-cell in the thymus and in mature T-cell function. Is constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors and plays a key role in T-cell antigen receptor(TCR)-linked signal transduction pathways (By similarity); Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (508 aa) |
| | SOX13 | SRY-box transcription factor 13. (666 aa) |
| | RAB29 | RAB29, member RAS oncogene family. (205 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | IL12B | Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa) |
| | ZAP70 | Tyrosine-protein kinase. (609 aa) |
| | CD276 | Uncharacterized protein. (314 aa) |
| | STOML2 | Stomatin like 2. (382 aa) |
| | MTOR | Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2521 aa) |
| | E1C066_CHICK | Uncharacterized protein. (258 aa) |
| | FOXN1 | Forkhead box N1. (636 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa) |
| | ABL1 | Tyrosine-protein kinase. (1111 aa) |
| | ADA | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenosine and 2- deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. May act as a positive regulator of T-cell coactivation (By similarity). Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. (357 aa) |
| | CARD11 | Uncharacterized protein. (1170 aa) |
| | F1NCI0_CHICK | DUF4704 domain-containing protein. (1936 aa) |
| | CRTAM | Uncharacterized protein. (439 aa) |
| | CD3E | T-cell surface glycoprotein CD3 epsilon chain; The CD3 complex mediates signal transduction, resulting in T- cell activation and proliferation. Required for normal immune responses. (175 aa) |
| | FADD | Fas associated via death domain. (195 aa) |
| | EGR1 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes (By similarity). Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Mediates responses to ischemia and hypoxia; regulates the express [...] (510 aa) |
| | IL18 | Interleukin-18; Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells. (198 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...] (573 aa) |
| | FGL2 | Fibrinogen C-terminal domain-containing protein. (439 aa) |
| | DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (709 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation. (304 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) |
| | NCSTN | Ncstrn_small domain-containing protein. (717 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1656 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2036 aa) |
| | BATF | Basic leucine zipper ATF-like transcription factor. (286 aa) |
| | AZI2 | 5-azacytidine induced 2. (397 aa) |
| | CCR9 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (382 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (145 aa) |
| | LOC768614 | Interferon type A3; Has antiviral activities; Belongs to the alpha/beta interferon family. (193 aa) |
| | BCL2 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa) |
| | JAG2 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1300 aa) |
| | IL7R | Interleukin-7 receptor alpha chain. (460 aa) |
| | IKZF3 | Uncharacterized protein. (509 aa) |
| | PTPN2 | Uncharacterized protein. (597 aa) |
| | RABL3 | Rab-like protein 3; Belongs to the small GTPase superfamily. Rab family. (236 aa) |
| | TRAF3IP2 | SEFIR domain-containing protein. (532 aa) |
| | GPR89A | Golgi pH regulator; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance. (455 aa) |
| | CD8A | Ig-like domain-containing protein. (207 aa) |
| | CYP26B1 | Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa) |
| | LEF1 | HMG box domain-containing protein. (412 aa) |
| | ENSGALP00000073699 | Uncharacterized protein. (163 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | LOC771880-2 | Ig-like domain-containing protein. (214 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (639 aa) |
| | ENSGALP00000073054 | Ig-like domain-containing protein. (206 aa) |
| | LOC100858762 | Uncharacterized protein. (193 aa) |
| | LOC396098 | Uncharacterized protein. (335 aa) |
| | ENSGALP00000072723 | Ig-like domain-containing protein. (216 aa) |
| | ENSGALP00000072274 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (126 aa) |
| | TNFRSF4 | Uncharacterized protein. (287 aa) |
| | RORA | Uncharacterized protein. (524 aa) |
| | CD3D | Ig_4 domain-containing protein. (179 aa) |
| | LOC100857403 | Interferon type A1/A2-like. (193 aa) |
| | CD8A-3 | Ig-like domain-containing protein. (318 aa) |
| | LOC107050371 | Uncharacterized protein. (1015 aa) |
| | LOC100857947 | Interferon type A1/A2-like. (193 aa) |
| | RIPK3 | Uncharacterized protein. (424 aa) |
| | LOC100859032 | Interferon type A1/A2-like. (193 aa) |
| | NCAPH2 | Non-SMC condensin II complex subunit H2. (727 aa) |
| | LOC100857744 | Interferon type A1/A2-like. (193 aa) |
| | IFNA3 | Interferon. (193 aa) |
| | TBX21 | T-box transcription factor 21. (580 aa) |
| | LOC112529934 | Ig-like domain-containing protein. (198 aa) |
| | ENSGALP00000069955 | Uncharacterized protein. (496 aa) |
| | FYN | Tyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling. (589 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1114 aa) |
| | LOC776018 | Uncharacterized protein. (193 aa) |
| | LOC100858177 | Interferon type A1/A2; Has antiviral activities. (193 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (187 aa) |
| | ARMC5 | Uncharacterized protein. (535 aa) |
| | GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) |
| | ENSGALP00000068753 | Ig-like domain-containing protein. (159 aa) |
| | ENSGALP00000068651 | Uncharacterized protein. (150 aa) |
| | TSC1 | Uncharacterized protein. (275 aa) |
| | CCL19 | C-C motif chemokine. (108 aa) |
| | CD2 | Uncharacterized protein. (301 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) |
| | TOX | Thymocyte selection associated high mobility group box. (525 aa) |
| | ENSGALP00000067311 | BEACH domain-containing protein. (161 aa) |
| | LOC100859414 | Uncharacterized protein. (193 aa) |
| | LOC107049158 | Ig-like domain-containing protein. (245 aa) |
| | ENSGALP00000066325 | Uncharacterized protein. (71 aa) |
| | ENSGALP00000066108 | Uncharacterized protein. (133 aa) |
| | ENSGALP00000065981 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (164 aa) |
| | SLA2 | Uncharacterized protein. (279 aa) |
| | CD4 | Uncharacterized protein. (487 aa) |
| | TCF7 | HMG box domain-containing protein. (397 aa) |
| | LOC112530215 | Sema domain-containing protein; Belongs to the semaphorin family. (606 aa) |
| | PTGER4 | Prostaglandin E2 receptor subtype 4; Belongs to the G-protein coupled receptor 1 family. (475 aa) |
| | TNFSF8 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (229 aa) |
| | NRARP | NOTCH regulated ankyrin repeat protein. (124 aa) |
| | LOC107053306 | Ig-like domain-containing protein. (212 aa) |
| | ENSGALP00000064025 | Ig-like domain-containing protein. (224 aa) |
| | CD83 | CD83 molecule. (215 aa) |
| | ENSGALP00000063593 | Ig-like domain-containing protein. (234 aa) |
| | CD74 | Invariant chain isoform p41. (286 aa) |
| | LOC771880 | Ig-like domain-containing protein. (228 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (480 aa) |
