STRINGSTRING
JDP2 JDP2 SORT1 SORT1 SIRT1 SIRT1 GPER1 GPER1 ZFPM1 ZFPM1 GATA3 GATA3 ADIPOQ ADIPOQ MMP11 MMP11 AXIN1 AXIN1 JAG1 JAG1 TRIO TRIO FLCN FLCN DDIT3 DDIT3 KALRN KALRN SIRT2 SIRT2 ZFPM2 ZFPM2 WISP1 WISP1 BBS12 BBS12 ZADH2 ZADH2 WWTR1 WWTR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JDP2BZIP domain-containing protein. (189 aa)
SORT1Sortilin. (954 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (881 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
ZFPM1Zinc finger protein, FOG family member 1. (1079 aa)
GATA3GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa)
ADIPOQC1q domain-containing protein. (244 aa)
MMP11Matrix metallopeptidase 11. (456 aa)
AXIN1Axin-1; Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. (841 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1216 aa)
TRIOTrio Rho guanine nucleotide exchange factor. (3076 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
DDIT3C/EBP-like protein. (155 aa)
KALRNKalirin RhoGEF kinase. (2980 aa)
SIRT2Deacetylase sirtuin-type domain-containing protein. (485 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
WISP1Uncharacterized protein. (359 aa)
BBS12Bardet-Biedl syndrome 12. (777 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (363 aa)
WWTR1WW domain containing transcription regulator 1. (386 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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