(26 nodes) Positive regulation of DNA replication network (Gallus gallus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

co-expression

protein homology

Your Input:
	RASAL3	Uncharacterized protein. (1938 aa)
	DBF4	DBF4 zinc finger. (709 aa)
	F1NFV8_CHICK	WSD domain-containing protein. (308 aa)
	EREG	EGF-like domain-containing protein. (153 aa)
	MAS1	MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (329 aa)
	SSBP1	Uncharacterized protein. (149 aa)
	CDT1	Chromatin licensing and DNA replication factor 1. (745 aa)
	MAP2K4	Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (426 aa)
	EGF	Uncharacterized protein. (1283 aa)
	FAF1	Fas associated factor 1. (650 aa)
	BAZ1A	Uncharacterized protein. (397 aa)
	E2F7	E2F transcription factor 7. (923 aa)
	CTC1	Uncharacterized protein. (1282 aa)
	DBF4B	DBF4-type domain-containing protein. (395 aa)
	ENSGALP00000054050	Uncharacterized protein. (171 aa)
	E2F8	E2F transcription factor 8. (738 aa)
	LPIN1	Lipin 1. (1003 aa)
	CIZ1	C2H2-type domain-containing protein. (651 aa)
	BRPF3	Bromodomain and PHD finger containing 3. (1215 aa)
	UCN	Urocortin. (100 aa)
	INO80	Uncharacterized protein. (1565 aa)
	STOML2	Stomatin like 2. (382 aa)
	ATAD5	AAA domain-containing protein. (1816 aa)
	DNA2	DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...] (992 aa)
	CDC7	Cell division cycle 7. (564 aa)
	ATRX	ATRX chromatin remodeler. (2420 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATAD5	BRPF3	ENSGALP00000005208	ENSGALP00000070100	AAA domain-containing protein.	Bromodomain and PHD finger containing 3.	0.796
ATAD5	CDC7	ENSGALP00000005208	ENSGALP00000009735	AAA domain-containing protein.	Cell division cycle 7.	0.405
ATAD5	CDT1	ENSGALP00000005208	ENSGALP00000022344	AAA domain-containing protein.	Chromatin licensing and DNA replication factor 1.	0.727
ATAD5	CTC1	ENSGALP00000005208	ENSGALP00000049175	AAA domain-containing protein.	Uncharacterized protein.	0.431
ATAD5	DNA2	ENSGALP00000005208	ENSGALP00000006419	AAA domain-containing protein.	DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...]	0.868
ATRX	SSBP1	ENSGALP00000012723	ENSGALP00000020973	ATRX chromatin remodeler.	Uncharacterized protein.	0.434
BAZ1A	ENSGALP00000054050	ENSGALP00000048277	ENSGALP00000054050	Uncharacterized protein.	Uncharacterized protein.	0.952
BAZ1A	F1NFV8_CHICK	ENSGALP00000048277	ENSGALP00000016270	Uncharacterized protein.	WSD domain-containing protein.	0.961
BRPF3	ATAD5	ENSGALP00000070100	ENSGALP00000005208	Bromodomain and PHD finger containing 3.	AAA domain-containing protein.	0.796
BRPF3	CDT1	ENSGALP00000070100	ENSGALP00000022344	Bromodomain and PHD finger containing 3.	Chromatin licensing and DNA replication factor 1.	0.517
CDC7	ATAD5	ENSGALP00000009735	ENSGALP00000005208	Cell division cycle 7.	AAA domain-containing protein.	0.405
CDC7	CDT1	ENSGALP00000009735	ENSGALP00000022344	Cell division cycle 7.	Chromatin licensing and DNA replication factor 1.	0.946
CDC7	DBF4	ENSGALP00000009735	ENSGALP00000014558	Cell division cycle 7.	DBF4 zinc finger.	0.999
CDC7	DBF4B	ENSGALP00000009735	ENSGALP00000050075	Cell division cycle 7.	DBF4-type domain-containing protein.	0.854
CDC7	DNA2	ENSGALP00000009735	ENSGALP00000006419	Cell division cycle 7.	DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...]	0.604
CDT1	ATAD5	ENSGALP00000022344	ENSGALP00000005208	Chromatin licensing and DNA replication factor 1.	AAA domain-containing protein.	0.727
CDT1	BRPF3	ENSGALP00000022344	ENSGALP00000070100	Chromatin licensing and DNA replication factor 1.	Bromodomain and PHD finger containing 3.	0.517
CDT1	CDC7	ENSGALP00000022344	ENSGALP00000009735	Chromatin licensing and DNA replication factor 1.	Cell division cycle 7.	0.946
CDT1	DBF4	ENSGALP00000022344	ENSGALP00000014558	Chromatin licensing and DNA replication factor 1.	DBF4 zinc finger.	0.948
CDT1	DNA2	ENSGALP00000022344	ENSGALP00000006419	Chromatin licensing and DNA replication factor 1.	DNA replication ATP-dependent helicase/nuclease DNA2; Key enzyme involved in DNA replication and DNA repair in nucleus and mitochondrion. Involved in Okazaki fragments processing by cleaving long flaps that escape FEN1: flaps that are longer than 27 nucleotides are coated by replication protein A complex (RPA), leading to recruit DNA2 which cleaves the flap until it is too short to bind RPA and becomes a substrate for FEN1. Also involved in 5'-end resection of DNA during double-strand break (DSB) repair by mediating the cleavage of 5'-ssDNA, while the 3'-ssDNA cleavage is prevented by [...]	0.642