(13 nodes) Positive regulation of epidermal growth factor-activated receptor activity network (Gallus gallus)

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second shell of interactors

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Your Input:
	AREG	Amphiregulin. (210 aa)
	HBEGF	Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...] (212 aa)
	NEURL1	Uncharacterized protein. (555 aa)
	EPGN	Epigen; Promotes the growth of epithelial cells. (151 aa)
	EREG	EGF-like domain-containing protein. (153 aa)
	LOC419074	Uncharacterized protein. (765 aa)
	ADAM17	Tumor necrosis factor alpha converting enzyme. (829 aa)
	NCF1C	Uncharacterized protein. (388 aa)
	TGFA	EGF-like domain-containing protein. (156 aa)
	BTC	Betacellulin. (171 aa)
	FBXW7	Uncharacterized protein. (586 aa)
	FBXW9	F-box domain-containing protein. (337 aa)
	ENSGALP00000073564	Uncharacterized protein. (243 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	AREG	ENSGALP00000030970	ENSGALP00000017644	Tumor necrosis factor alpha converting enzyme.	Amphiregulin.	0.499
ADAM17	EREG	ENSGALP00000030970	ENSGALP00000017642	Tumor necrosis factor alpha converting enzyme.	EGF-like domain-containing protein.	0.453
ADAM17	HBEGF	ENSGALP00000030970	ENSGALP00000001399	Tumor necrosis factor alpha converting enzyme.	Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...]	0.504
ADAM17	TGFA	ENSGALP00000030970	ENSGALP00000039726	Tumor necrosis factor alpha converting enzyme.	EGF-like domain-containing protein.	0.541
AREG	ADAM17	ENSGALP00000017644	ENSGALP00000030970	Amphiregulin.	Tumor necrosis factor alpha converting enzyme.	0.499
AREG	BTC	ENSGALP00000017644	ENSGALP00000041051	Amphiregulin.	Betacellulin.	0.956
AREG	EPGN	ENSGALP00000017644	ENSGALP00000017636	Amphiregulin.	Epigen; Promotes the growth of epithelial cells.	0.935
AREG	EREG	ENSGALP00000017644	ENSGALP00000017642	Amphiregulin.	EGF-like domain-containing protein.	0.989
AREG	HBEGF	ENSGALP00000017644	ENSGALP00000001399	Amphiregulin.	Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...]	0.615
AREG	TGFA	ENSGALP00000017644	ENSGALP00000039726	Amphiregulin.	EGF-like domain-containing protein.	0.851
BTC	AREG	ENSGALP00000041051	ENSGALP00000017644	Betacellulin.	Amphiregulin.	0.956
BTC	EPGN	ENSGALP00000041051	ENSGALP00000017636	Betacellulin.	Epigen; Promotes the growth of epithelial cells.	0.933
BTC	EREG	ENSGALP00000041051	ENSGALP00000017642	Betacellulin.	EGF-like domain-containing protein.	0.975
BTC	HBEGF	ENSGALP00000041051	ENSGALP00000001399	Betacellulin.	Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...]	0.922
BTC	TGFA	ENSGALP00000041051	ENSGALP00000039726	Betacellulin.	EGF-like domain-containing protein.	0.534
ENSGALP00000073564	FBXW7	ENSGALP00000073564	ENSGALP00000050497	Uncharacterized protein.	Uncharacterized protein.	0.899
EPGN	AREG	ENSGALP00000017636	ENSGALP00000017644	Epigen; Promotes the growth of epithelial cells.	Amphiregulin.	0.935
EPGN	BTC	ENSGALP00000017636	ENSGALP00000041051	Epigen; Promotes the growth of epithelial cells.	Betacellulin.	0.933
EPGN	EREG	ENSGALP00000017636	ENSGALP00000017642	Epigen; Promotes the growth of epithelial cells.	EGF-like domain-containing protein.	0.953
EPGN	HBEGF	ENSGALP00000017636	ENSGALP00000001399	Epigen; Promotes the growth of epithelial cells.	Proheparin-binding EGF-like growth factor; May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF (By similarity). Plays an important role in the proper development of cranial nerves by inhibiting the migration of the cranial neural crest cells (NCCs) into the odd-numbered neuromeres (r3 and r5) of the hindbrain Plays a role in mediating v-Jun-induced oncogenic tra [...]	0.739