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INO80 | Uncharacterized protein. (1565 aa) | ||||
YTHDC2 | YTH domain containing 2. (1446 aa) | ||||
CDC27 | Uncharacterized protein. (833 aa) | ||||
IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (175 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) | ||||
GPSM2 | G protein signaling modulator 2. (663 aa) | ||||
LSM10 | LSM10, U7 small nuclear RNA associated. (123 aa) | ||||
KIF14 | Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1616 aa) | ||||
CDC73 | Parafibromin; Tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. May be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression. Component of the PAF1 complex (PAF1C) which has multiple functions during transcription by RNA polymerase II. PAF1C associates with RNA polymerase II, is involved in transcriptional elongation and in histone modifications including methylation on histone H3 'Lys-4' (H3K4me3) (By similarity). (531 aa) | ||||
POLDIP2 | ApaG domain-containing protein. (373 aa) | ||||
HSF4 | HSF_DOMAIN domain-containing protein. (510 aa) | ||||
ATAD5 | AAA domain-containing protein. (1816 aa) | ||||
CCND3 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (292 aa) | ||||
FBXO42 | F-box protein 42. (764 aa) | ||||
ANAPC7 | Anaphase promoting complex subunit 7. (565 aa) | ||||
MAD1L1 | Mitotic arrest deficient 1 like 1. (717 aa) | ||||
SLC6A4 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (670 aa) | ||||
CENPV | GFA domain-containing protein. (207 aa) | ||||
CUL3 | Cullin 3; Belongs to the cullin family. (768 aa) | ||||
CDC14A | Uncharacterized protein. (603 aa) | ||||
KLHL18 | BTB domain-containing protein. (581 aa) | ||||
PKD1 | Polycystin 1, transient receptor potential channel interacting. (4382 aa) | ||||
CDC7 | Cell division cycle 7. (564 aa) | ||||
NSFL1C | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. (379 aa) | ||||
NCAPG2 | Non-SMC condensin II complex subunit G2. (1144 aa) | ||||
CCND1 | G1/S-specific cyclin-D1; Essential for the control of the cell cycle at the G1/S (start) transition. Interacts with the CDK4 and CDK6 protein kinases. May play a role in transcriptional regulation (By similarity). (292 aa) | ||||
CDC23 | Cell division cycle 23. (595 aa) | ||||
DRD2 | Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa) | ||||
ATRX | ATRX chromatin remodeler. (2420 aa) | ||||
SLF2 | SMC5-SMC6 complex localization factor 2. (1189 aa) | ||||
KMT2E | Lysine methyltransferase 2E. (1814 aa) | ||||
PSMD10 | ANK_REP_REGION domain-containing protein. (226 aa) | ||||
CCNYL1 | Cyclin Y like 1; Belongs to the cyclin family. (365 aa) | ||||
TTL | Uncharacterized protein. (378 aa) | ||||
DDR1 | Uncharacterized protein. (873 aa) | ||||
GIPC2 | GIPC PDZ domain containing family member 2. (318 aa) | ||||
DBF4 | DBF4 zinc finger. (709 aa) | ||||
ECT2 | Epithelial cell transforming 2. (914 aa) | ||||
ASNS | Asparagine synthetase [glutamine-hydrolyzing]. (561 aa) | ||||
PLK4 | POLO box domain-containing protein. (566 aa) | ||||
SPAST | Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...] (613 aa) | ||||
LGMN | Legumain. (431 aa) | ||||
EPGN | Epigen; Promotes the growth of epithelial cells. (151 aa) | ||||
EREG | EGF-like domain-containing protein. (153 aa) | ||||
CCNK | Uncharacterized protein; Belongs to the cyclin family. (587 aa) | ||||
DAZL | Deleted in azoospermia-like; RNA-binding protein, which probably plays a central role in gametogenesis in both males and females. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and promoting the translation of key transcripts (By similarity); Belongs to the RRM DAZ family. (289 aa) | ||||
LOC429032 | Rho-GAP domain-containing protein. (568 aa) | ||||
MNAT1 | CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa) | ||||
PDGFB | PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (251 aa) | ||||
CCNT2 | Uncharacterized protein. (501 aa) | ||||
EDN1 | Endothelin 1. (194 aa) | ||||
RHNO1 | Uncharacterized protein. (264 aa) | ||||
CDT1 | Chromatin licensing and DNA replication factor 1. (745 aa) | ||||
CITED2 | Cited2/melanocyte specific gene-related gene 1 MRG1. (236 aa) | ||||
ZPR1 | ZPR1 zinc finger. (447 aa) | ||||
NDC80 | Kinetochore protein NDC80 homolog; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules. May play a role in chromosome congression and may be essential for the end-on attachment of the kinetochores t [...] (640 aa) | ||||
MSX1 | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. (288 aa) | ||||
DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (425 aa) | ||||
SMC5 | Structural maintenance of chromosomes protein 5; Core component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination and mediates sumoylation of shelterin complex (telosome) components. Required for recruitment of telomeres to PML nuclear bodies. Required for sister chromatid cohesion during prometaphase and mitotic progression; [...] (1065 aa) | ||||
CPSF3 | Cleavage and polyadenylation specific factor 3. (691 aa) | ||||
RRM2 | Ribonucleotide reductase regulatory subunit M2. (384 aa) | ||||
GEN1 | GEN1 Holliday junction 5' flap endonuclease. (941 aa) | ||||
PBK | Protein kinase domain-containing protein. (322 aa) | ||||
CDC16 | TPR_REGION domain-containing protein. (623 aa) | ||||
TFDP1 | Transcription factor. (411 aa) | ||||
CUL4A | Cullin 4A; Belongs to the cullin family. (767 aa) | ||||
RGCC | Regulator of cell cycle. (135 aa) | ||||
BRCA2 | Tower domain-containing protein. (3397 aa) | ||||
CCND2 | G1/S-specific cyclin-D2; Essential for the control of the cell cycle at the G1/S (start) transition; Belongs to the cyclin family. Cyclin D subfamily. (291 aa) | ||||
RAD51AP1 | Uncharacterized protein. (255 aa) | ||||
RRM1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (790 aa) | ||||
SPDYA | Speedy/RINGO cell cycle regulator family member A. (324 aa) | ||||
ADAM17 | Tumor necrosis factor alpha converting enzyme. (829 aa) | ||||
TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (412 aa) | ||||
NCAPH | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (729 aa) | ||||
ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) | ||||
SMC4 | Structural maintenance of chromosomes protein. (1300 aa) | ||||
FGF8 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Involved in initiation, outgrowth and patterning of the limbs; Belongs to the heparin-binding growth factors family. (214 aa) | ||||
C26H6orf89 | Uncharacterized protein. (328 aa) | ||||
APP | BPTI/Kunitz inhibitor domain-containing protein. (751 aa) | ||||
DYNC1H1 | Dynein cytoplasmic 1 heavy chain 1. (4652 aa) | ||||
STRA8 | Stimulated by retinoic acid 8. (282 aa) | ||||
ANAPC5 | Anaphase-promoting complex subunit 5; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains (By similarity). (756 aa) | ||||
TGFA | EGF-like domain-containing protein. (156 aa) | ||||
LOC769510 | Uncharacterized protein. (889 aa) | ||||
BTC | Betacellulin. (171 aa) | ||||
CRNN | EF-hand domain-containing protein. (384 aa) | ||||
MAD2L1BP | MAD2L1 binding protein. (282 aa) | ||||
UBE2C | Ubiquitin conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (179 aa) | ||||
CXCR5 | Chemokine receptor; Belongs to the G-protein coupled receptor 1 family. (371 aa) | ||||
ENSGALP00000044025 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (617 aa) | ||||
SIRT2 | Deacetylase sirtuin-type domain-containing protein. (485 aa) | ||||
SMPD3 | Sphingomyelin phosphodiesterase 3. (662 aa) | ||||
USP19 | Ubiquitin specific peptidase 19. (1434 aa) | ||||
TBX3 | T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. (732 aa) | ||||
LFNG | Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe; Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules. Essential mediator of somite segmentation and patterning. (363 aa) | ||||
LSM11 | LSM11, U7 small nuclear RNA associated. (361 aa) | ||||
RCC2 | Regulator of chromosome condensation 2. (529 aa) | ||||
PAF1 | PAF1 homolog, Paf1/RNA polymerase II complex component. (488 aa) | ||||
UBXN2B | UBX domain-containing protein 2B; Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. Regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. (402 aa) | ||||
FEN1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (381 aa) | ||||
CDK5R1 | Cyclin dependent kinase 5 regulatory subunit 1. (300 aa) | ||||
CCNY | Cyclin Y; Belongs to the cyclin family. (341 aa) | ||||
RAD51C | RAD51 paralog C. (360 aa) | ||||
E2F7 | E2F transcription factor 7. (923 aa) | ||||
PKD2 | Uncharacterized protein. (881 aa) | ||||
NUMA1 | Uncharacterized protein. (2226 aa) | ||||
CUL4B | Cullin 4B; Belongs to the cullin family. (883 aa) | ||||
CEP295 | ALMS_motif domain-containing protein. (1947 aa) | ||||
CCPG1 | Cell cycle progression protein 1; May be involved in the regulation of Rho-mediated signaling pathways and in cell cycle regulation; Belongs to the CCPG1 family. (801 aa) | ||||
CHEK2 | Uncharacterized protein. (524 aa) | ||||
DBF4B | DBF4-type domain-containing protein. (395 aa) | ||||
ENSGALP00000050097 | Protein kinase domain-containing protein. (109 aa) | ||||
IL1B | Interleukin-1; Belongs to the IL-1 family. (267 aa) | ||||
DDR2 | Discoidin domain receptor tyrosine kinase 2. (901 aa) | ||||
KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (972 aa) | ||||
ENSGALP00000050982 | Uncharacterized protein. (280 aa) | ||||
NCAPG | Non-SMC condensin I complex subunit G. (1038 aa) | ||||
CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) | ||||
LOC112533511 | Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (593 aa) | ||||
DUSP3 | Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa) | ||||
RRM2B | Ribonucleotide reductase regulatory TP53 inducible subunit M2B. (353 aa) | ||||
LRP6 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1580 aa) | ||||
NSMCE2 | SP-RING-type domain-containing protein. (239 aa) | ||||
TPR | Translocated promoter region, nuclear basket protein. (2472 aa) | ||||
FOXG1 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. (451 aa) | ||||
E2F8 | E2F transcription factor 8. (738 aa) | ||||
MAPK15 | Mitogen-activated protein kinase. (528 aa) | ||||
RACGAP1 | Rac GTPase activating protein 1. (638 aa) | ||||
RASAL3 | Uncharacterized protein. (1938 aa) | ||||
HSF3 | Heat shock factor protein 3; DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. HSF3 binds DNA constitutively only when the C-terminal region is deleted; Belongs to the HSF family. (551 aa) | ||||
ANKRD17 | Ankyrin repeat domain 17. (2593 aa) | ||||
CDC14B | Uncharacterized protein. (499 aa) | ||||
HSF1 | Heat shock factor protein 1; Functions as a stress-inducible and DNA-binding transcription factor that plays a central role in the transcriptional activation of the heat shock response (HSR), leading to the expression of a large class of molecular chaperones heat shock proteins (HSPs) that protect cells from cellular insults' damage. In unstressed cells, is present in a HSP90-containing multichaperone complex that maintains it in a non-DNA-binding inactivated monomeric form. Upon exposure to heat and other stress stimuli, undergoes homotrimerization and activates HSP gene transcription [...] (343 aa) | ||||
CDC25A | Rhodanese domain-containing protein. (526 aa) | ||||
TBX2 | T-box transcription factor 2. (693 aa) | ||||
CCDC57 | Uncharacterized protein. (588 aa) | ||||
GIPC3 | GIPC PDZ domain containing family member 3. (539 aa) | ||||
FAM83D | FAM83 domain-containing protein. (562 aa) | ||||
XRCC3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (382 aa) | ||||
MAD2L1 | HORMA domain-containing protein. (206 aa) | ||||
PLRG1 | Pleiotropic regulator 1. (516 aa) | ||||
THOC1 | Death domain-containing protein. (671 aa) | ||||
HSP90AA1 | Heat shock protein HSP 90-alpha; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a ra [...] (771 aa) | ||||
PCID2 | PCI domain-containing protein. (399 aa) | ||||
THOC5 | THO complex subunit 5 homolog; Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway (By similarity); Belongs to t [...] (698 aa) | ||||
CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) | ||||
STIL | STIL centriolar assembly protein. (1330 aa) | ||||
ROCK2 | Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1483 aa) | ||||
MAP10 | HPHLAWLY domain-containing protein. (906 aa) | ||||
RANBP1 | RanBD1 domain-containing protein. (252 aa) | ||||
CDC42 | Cell division control protein 42 homolog; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Regulates cell migration. Plays a role in the extension and maintenance of the formation of thin, actin- rich surface projections called filopodia. Also plays a role in phagocytos [...] (194 aa) | ||||
ENSGALP00000066664 | CYCLIN domain-containing protein; Belongs to the cyclin family. (180 aa) | ||||
MAP3K20 | Uncharacterized protein. (791 aa) | ||||
MEPCE | Methylphosphate capping enzyme. (628 aa) | ||||
STXBP4 | Syntaxin binding protein 4. (736 aa) | ||||
CDC6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (554 aa) | ||||
CCNT1 | Cyclin T1; Belongs to the cyclin family. (730 aa) | ||||
CEP120 | Centrosomal protein 120. (1006 aa) | ||||
CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa) | ||||
CSPP1 | Uncharacterized protein. (416 aa) | ||||
CDC25B | Cell division cycle 25B. (555 aa) | ||||
RAD51B | RAD51 paralog B. (415 aa) | ||||
DDX11 | DEAD/H-box helicase 11. (908 aa) | ||||
SVIL | Supervillin. (2303 aa) | ||||
FAM178B | Uncharacterized protein. (653 aa) | ||||
FAM83D-2 | FAM83 domain-containing protein. (184 aa) | ||||
SLF1 | SMC5-SMC6 complex localization factor 1. (981 aa) | ||||
PPP1R10 | Protein phosphatase 1 regulatory subunit 10. (453 aa) | ||||
MECP2 | Methyl-CpG binding protein 2. (208 aa) | ||||
BCL2L11 | BCL2 like 11. (179 aa) | ||||
NCAPH2 | Non-SMC condensin II complex subunit H2. (727 aa) | ||||
RB1 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] (984 aa) | ||||
ENSGALP00000071775 | RING-type domain-containing protein. (343 aa) | ||||
SPAG5 | Uncharacterized protein. (1431 aa) | ||||
RPTOR | Regulatory associated protein of MTOR complex 1. (1374 aa) | ||||
GIPC1 | GIPC PDZ domain containing family member 1. (552 aa) | ||||
MBLAC1 | Metallo-beta-lactamase domain containing 1. (369 aa) | ||||
MAPK15-2 | Protein kinase domain-containing protein. (305 aa) | ||||
MEIOC | Meiosis specific with coiled-coil domain. (911 aa) |