(15 nodes) Positive regulation of fatty acid metabolic process network (Gallus gallus)

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Your Input:
	MLYCD	Malonyl-CoA decarboxylase. (501 aa)
	SLC45A3	Solute carrier family 45 member 3. (569 aa)
	ADIPOQ	C1q domain-containing protein. (244 aa)
	MLXIPL	BHLH domain-containing protein. (895 aa)
	ANXA1	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa)
	NR1H3	Uncharacterized protein. (519 aa)
	PPARD	Uncharacterized protein. (545 aa)
	PPARG	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (498 aa)
	CD74	Invariant chain isoform p41. (286 aa)
	APOA1	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa)
	PPARA	Uncharacterized protein. (468 aa)
	ABCD2	Uncharacterized protein. (730 aa)
	IL1B	Interleukin-1; Belongs to the IL-1 family. (267 aa)
	LPGAT1	PlsC domain-containing protein. (400 aa)
	MID1IP1	THRSP-like protein. (159 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCD2	MLXIPL	ENSGALP00000052341	ENSGALP00000047840	Uncharacterized protein.	BHLH domain-containing protein.	0.408
ADIPOQ	ANXA1	ENSGALP00000008899	ENSGALP00000032184	C1q domain-containing protein.	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	0.411
ADIPOQ	APOA1	ENSGALP00000008899	ENSGALP00000011510	C1q domain-containing protein.	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	0.528
ADIPOQ	IL1B	ENSGALP00000008899	ENSGALP00000050171	C1q domain-containing protein.	Interleukin-1; Belongs to the IL-1 family.	0.744
ADIPOQ	PPARA	ENSGALP00000008899	ENSGALP00000053048	C1q domain-containing protein.	Uncharacterized protein.	0.798
ADIPOQ	PPARD	ENSGALP00000008899	ENSGALP00000072840	C1q domain-containing protein.	Uncharacterized protein.	0.519
ADIPOQ	PPARG	ENSGALP00000008899	ENSGALP00000067699	C1q domain-containing protein.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.899
ANXA1	ADIPOQ	ENSGALP00000032184	ENSGALP00000008899	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	C1q domain-containing protein.	0.411
ANXA1	IL1B	ENSGALP00000032184	ENSGALP00000050171	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	Interleukin-1; Belongs to the IL-1 family.	0.461
APOA1	ADIPOQ	ENSGALP00000011510	ENSGALP00000008899	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	C1q domain-containing protein.	0.528
APOA1	NR1H3	ENSGALP00000011510	ENSGALP00000073715	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	Uncharacterized protein.	0.485
APOA1	PPARA	ENSGALP00000011510	ENSGALP00000053048	Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family.	Uncharacterized protein.	0.452
CD74	IL1B	ENSGALP00000063230	ENSGALP00000050171	Invariant chain isoform p41.	Interleukin-1; Belongs to the IL-1 family.	0.459
IL1B	ADIPOQ	ENSGALP00000050171	ENSGALP00000008899	Interleukin-1; Belongs to the IL-1 family.	C1q domain-containing protein.	0.744
IL1B	ANXA1	ENSGALP00000050171	ENSGALP00000032184	Interleukin-1; Belongs to the IL-1 family.	Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...]	0.461
IL1B	CD74	ENSGALP00000050171	ENSGALP00000063230	Interleukin-1; Belongs to the IL-1 family.	Invariant chain isoform p41.	0.459
IL1B	PPARA	ENSGALP00000050171	ENSGALP00000053048	Interleukin-1; Belongs to the IL-1 family.	Uncharacterized protein.	0.543
IL1B	PPARG	ENSGALP00000050171	ENSGALP00000067699	Interleukin-1; Belongs to the IL-1 family.	Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]	0.799
MLXIPL	ABCD2	ENSGALP00000047840	ENSGALP00000052341	BHLH domain-containing protein.	Uncharacterized protein.	0.408
MLXIPL	NR1H3	ENSGALP00000047840	ENSGALP00000073715	BHLH domain-containing protein.	Uncharacterized protein.	0.546