STRINGSTRING
SGPL1 SGPL1 LOC426626 LOC426626 PDGFD PDGFD PDGFRA PDGFRA ABL2 ABL2 BCAR1 BCAR1 PDGFRB PDGFRB CSRNP1 CSRNP1 FREM3 FREM3 PDGFRL PDGFRL ZFAND5 ZFAND5 PDGFB PDGFB PDGFC PDGFC PTPRJ PTPRJ ABL1 ABL1 PLAT PLAT ITGB3 ITGB3 TXNIP TXNIP STON1 STON1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGPL1Uncharacterized protein. (574 aa)
LOC426626Uncharacterized protein. (228 aa)
PDGFDUncharacterized protein; Belongs to the PDGF/VEGF growth factor family. (389 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. Required for normal development of the gastrointestinal tract. Plays a role in cell migration and chemotaxis in wound he [...] (1106 aa)
ABL2Tyrosine-protein kinase. (1159 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (905 aa)
PDGFRBPlatelet derived growth factor receptor beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1073 aa)
CSRNP1Cysteine and serine rich nuclear protein 1. (469 aa)
FREM3Uncharacterized protein. (2495 aa)
PDGFRLPlatelet derived growth factor receptor like. (374 aa)
ZFAND5Uncharacterized protein. (334 aa)
PDGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (251 aa)
PDGFCPlatelet-derived growth factor C, receptor-binding form; Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, in angiogenesis and blood vessel development (By similarity). (345 aa)
PTPRJReceptor-type tyrosine-protein phosphatase eta; Tyrosine phosphatase which dephosphorylates or contributes to the dephosphorylation of several substrates. Plays a role in cell adhesion, migration, proliferation and differentiation (By similarity). May influence the potential of nonsensory supporting cells to either proliferate or differentiate into hair cells; Belongs to the protein-tyrosine phosphatase family. Receptor class 3 subfamily. (1455 aa)
ABL1Tyrosine-protein kinase. (1111 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (567 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (781 aa)
TXNIPThioredoxin interacting protein. (430 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (823 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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