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GIGYF2 | GYF domain-containing protein. (1278 aa) | ||||
TSC2 | TSC complex subunit 2. (1872 aa) | ||||
IGF1 | Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex fo [...] (153 aa) | ||||
EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1085 aa) | ||||
IGFBP5 | Insulin like growth factor binding protein 5. (269 aa) | ||||
GHSR | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (561 aa) | ||||
AR | Uncharacterized protein. (703 aa) | ||||
GHR | Growth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway; Belongs to the type I cytokine receptor family. Type 1 subfamily. (646 aa) |