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XKR8 | XK-related protein. (414 aa) | ||||
BTN1 | B30.2/SPRY domain-containing protein. (424 aa) | ||||
CASP3 | Caspase-3; Belongs to the peptidase C14A family. (283 aa) | ||||
GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) | ||||
C5H15orf41 | Protein C15orf41 homolog; May play a role in erythroid cell differentiation. (315 aa) | ||||
LOC112530162 | Uncharacterized protein. (159 aa) | ||||
RC3H1 | Ring finger and CCCH-type domains 1. (1114 aa) | ||||
DOCK10 | Dedicator of cytokinesis 10; Belongs to the DOCK family. (2212 aa) | ||||
BAK1 | Uncharacterized protein. (216 aa) | ||||
CEBPG | Leucine zipper transcription factor. (150 aa) | ||||
UBAP2 | Uncharacterized protein. (862 aa) | ||||
SRF | Serum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa) | ||||
FLT3 | Fms related tyrosine kinase 3. (877 aa) | ||||
MERTK | Uncharacterized protein. (990 aa) | ||||
IL7 | Interleukin-7. (146 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1319 aa) | ||||
KIT | Mast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. In response to KITLG/SCF binding, KIT can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. Activated KIT also transmits signals via [...] (960 aa) | ||||
CCR4 | C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (358 aa) | ||||
SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (943 aa) | ||||
ATPIF1 | Uncharacterized protein. (92 aa) | ||||
LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (952 aa) | ||||
ADGRG1 | Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (695 aa) | ||||
SMO | Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). (816 aa) | ||||
NKX2-6 | Homeobox domain-containing protein. (193 aa) | ||||
NKX2-3 | Homeobox domain-containing protein. (328 aa) | ||||
CCR7 | C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa) | ||||
SLC25A38 | Mitochondrial glycine transporter; Mitochondrial glycine transporter that imports glycine into the mitochondrial matrix. Plays an important role in providing glycine for the first enzymatic step in heme biosynthesis, the condensation of glycine with succinyl-CoA to produce 5-aminolevulinate (ALA) in the miochondrial matrix. Required during erythropoiesis. Belongs to the mitochondrial carrier (TC 2.A.29) family. SLC25A38 subfamily. (288 aa) | ||||
PRDM14 | PR/SET domain 14. (514 aa) | ||||
CDH15 | Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa) | ||||
LYN | Tyrosine-protein kinase. (491 aa) | ||||
TNFAIP3 | TNF alpha induced protein 3. (806 aa) | ||||
CCN3 | CCN family member 3; Immediate-early protein likely to play a role in cell growth regulation. Its overexpression is associated with tumorigenesis and expression of a N-terminal-truncated version of CCN3 gene in chicken embryonic fibroblasts (CEF) is sufficient to induce the transformation of CEF in vitro. (351 aa) | ||||
SP3 | Transcription factor Sp3; Transcriptional factor that can act as an activator or repressor depending on post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription (By similarity). Required for activation of SPARC transcription; Belongs to the Sp1 C2H2-type zinc-finger protein family. (771 aa) | ||||
ALAS1 | 5-aminolevulinate synthase, nonspecific, mitochondrial; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (635 aa) | ||||
SLC40A1 | Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (581 aa) | ||||
PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa) | ||||
ENSGALP00000044025 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (617 aa) | ||||
CDK5RAP3 | Uncharacterized protein. (619 aa) | ||||
SLC46A2 | Solute carrier family 46 member 2. (453 aa) | ||||
TNFRSF13B | TNFR-Cys domain-containing protein. (259 aa) | ||||
ACE | Angiotensin-converting enzyme; Converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin; Belongs to the peptidase M2 family. (1281 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa) | ||||
PLA2G10 | Phospholipase A(2). (155 aa) | ||||
ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) | ||||
WDR48 | WD repeat-containing protein 48; Regulator of deubiquitinating complexes. Acts as a strong activator of USP1 and USP46. Enhances the USP1-mediated deubiquitination of FANCD2; USP1 being almost inactive by itself. Also activates deubiquitinating activity of complexes containing USP12. Activates deubiquitination by increasing the catalytic turnover without increasing the affinity of deubiquitinating enzymes for the substrate. May play a role in vesicular transport or membrane fusion events necessary for transport to lysosomes. (678 aa) | ||||
PLA2G10L | Phospholipase A(2). (158 aa) | ||||
ARHGEF5 | Uncharacterized protein. (1733 aa) | ||||
GPR183 | G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (371 aa) | ||||
TNFSF13B | TNF family B cell activation factor; Belongs to the tumor necrosis factor family. (288 aa) | ||||
PKNOX1 | PBX/knotted 1 homeobox 1. (436 aa) | ||||
UFL1 | E3 UFM1-protein ligase 1; E3 UFM1-protein ligase that mediates ufmylation of target proteins; Belongs to the UFL1 family. (789 aa) | ||||
CDH2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa) | ||||
TRAF3IP2 | SEFIR domain-containing protein. (532 aa) | ||||
LYAR | Ly1 antibody reactive. (364 aa) | ||||
FSTL1 | Uncharacterized protein. (315 aa) | ||||
GCNT4 | Glucosaminyl (N-acetyl) transferase 4. (455 aa) | ||||
PTPN2 | Uncharacterized protein. (597 aa) | ||||
MYCT1 | MYC target 1. (192 aa) | ||||
IL7R | Interleukin-7 receptor alpha chain. (460 aa) | ||||
MAEA | E3 ubiquitin-protein transferase MAEA; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. MAEA is required for normal cell proliferation. The CTLH E3 ubiquitin- protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (By similarity). Plays a role in erythroblast maturati [...] (396 aa) | ||||
IL20RB | Interleukin 20 receptor subunit beta. (312 aa) | ||||
FH | Uncharacterized protein. (507 aa) | ||||
BCL2 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa) | ||||
SERPINB10B | Heterochromatin-associated protein MENT; DNA-binding protein that promotes DNA condensation into transcriptionally inactive heterochromatin in terminally differentiated avian blood cells. Promotes tight packing of nucleosomes into spherical clusters by binding to linker DNA and subsequent oligomerization. Acts as a cysteine protease inhibitor towards CTSL (cathepsin L1) and CTSV (cathepsin L2), but does not inhibit serine proteases. Belongs to the serpin family. Ov-serpin subfamily. (410 aa) | ||||
FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (559 aa) | ||||
MB | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa) | ||||
SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1330 aa) | ||||
RCOR1 | REST corepressor 1. (449 aa) | ||||
ABCB10 | ATP binding cassette subfamily B member 10. (523 aa) | ||||
PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (461 aa) | ||||
NCSTN | Ncstrn_small domain-containing protein. (717 aa) | ||||
VPS54 | VPS54 subunit of GARP complex. (974 aa) | ||||
GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) | ||||
NAPEPLD | Lactamase_B domain-containing protein. (463 aa) | ||||
KMT2E | Lysine methyltransferase 2E. (1814 aa) | ||||
SLC37A4 | Solute carrier family 37 member 4. (451 aa) | ||||
FADD | Fas associated via death domain. (195 aa) | ||||
BCL6 | B-cell lymphoma 6 protein homolog; Transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. Forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Represses its target genes by binding directly to the DNA sequence 5'-TTCCTAGAA-3' (BCL6-binding site) or indirectly by repressing the transcriptional activity of transcription factors. In GC B-cells, repres [...] (708 aa) | ||||
NCAPG2 | Non-SMC condensin II complex subunit G2. (1144 aa) | ||||
CAMLG | Calcium signal-modulating cyclophilin ligand; Likely involved in the mobilization of calcium as a result of the TCR/CD3 complex interaction. Binds to cyclophilin B. (289 aa) | ||||
SHH | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (425 aa) | ||||
SCNN1B | Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (667 aa) | ||||
LOC407092 | UBA domain-containing protein. (1109 aa) | ||||
NLE1 | Notchless homolog 1. (482 aa) | ||||
SH2B3 | SH2B adaptor protein 3. (539 aa) | ||||
CARD11 | Uncharacterized protein. (1170 aa) | ||||
CCNB1 | G2/mitotic-specific cyclin-B2; Essential for the control of the cell cycle at the G2/M (mitosis) transition. (399 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa) | ||||
FOXN1 | Forkhead box N1. (636 aa) | ||||
KLHL10 | BTB domain-containing protein. (584 aa) | ||||
LGALS2 | Galectin. (131 aa) | ||||
LRRC45 | Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion. (670 aa) | ||||
HSPA9 | Stress-70 protein, mitochondrial; Chaperone protein which plays an important role in mitochondrial iron-sulfur cluster (ISC) biogenesis. Interacts with and stabilizes ISC cluster assembly proteins FXN, NFU1, NFS1 and ISCU. Regulates erythropoiesis via stabilization of ISC assembly. May play a role in the control of cell proliferation and cellular aging. Belongs to the heat shock protein 70 family. (675 aa) | ||||
CARD9 | Caspase recruitment domain family member 9. (574 aa) | ||||
ST6GALNAC1 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1. (566 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) | ||||
SPNS2 | Sphingolipid transporter 2. (510 aa) | ||||
RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) | ||||
ARID4A | ARID domain-containing protein. (1252 aa) | ||||
ENSGALP00000070609 | Uncharacterized protein. (335 aa) | ||||
BCL2L11 | BCL2 like 11. (179 aa) | ||||
RB1 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] (984 aa) | ||||
KCNQ1 | Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (863 aa) | ||||
LOC112530285 | SAP domain-containing protein. (172 aa) | ||||
ENSGALP00000072274 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (126 aa) | ||||
ADGRF5 | Adhesion G protein-coupled receptor F5; Belongs to the G-protein coupled receptor 2 family. (1342 aa) | ||||
JAK2 | Tyrosine-protein kinase JAK2; Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with cytokine receptors. Following ligand-binding to cell surface receptors, phosphorylates specific tyrosine residues on the cytoplasmic tails of the receptor, creating docking sites for STATs proteins. Subsequently, phosphorylates the STATs proteins once they are recru [...] (1165 aa) | ||||
CASP14 | Caspase-17/a; Belongs to the peptidase C14A family. (266 aa) | ||||
SKIL | c-SKI_SMAD_bind domain-containing protein. (690 aa) | ||||
GIGYF2 | GYF domain-containing protein. (1278 aa) | ||||
UBAP2L | Ubiquitin associated protein 2 like. (1125 aa) | ||||
CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) | ||||
SASH3 | Uncharacterized protein. (382 aa) | ||||
UBA5 | Ubiquitin-like modifier-activating enzyme 5; E1-like enzyme which activates UFM1 and SUMO2; Belongs to the ubiquitin-activating E1 family. UBA5 subfamily. (394 aa) | ||||
EPAS1 | Endothelial PAS domain protein 1. (867 aa) | ||||
HOXB6 | Homeobox protein Hox-B6; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Antp homeobox family. (222 aa) | ||||
LRRC19 | Uncharacterized protein. (176 aa) | ||||
LPCAT3 | Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (501 aa) | ||||
GPI | Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (181 aa) | ||||
SERPINB10A | SERPIN domain-containing protein; Belongs to the serpin family. (423 aa) | ||||
TMEM14C | Uncharacterized protein. (107 aa) | ||||
CSF1 | Uncharacterized protein. (493 aa) | ||||
JAM3 | Junctional adhesion molecule 3. (458 aa) | ||||
DMTN | AbLIM_anchor domain-containing protein. (687 aa) | ||||
ENSGALP00000065981 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (164 aa) | ||||
ADAR | RNA-specific Adenosine deaminase Transcript variant M. (1153 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) | ||||
ZFPM1 | Zinc finger protein, FOG family member 1. (1079 aa) | ||||
GLIS2 | Uncharacterized protein. (649 aa) |