Your Input: | |||||
LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (909 aa) | ||||
EREG | EGF-like domain-containing protein. (153 aa) | ||||
AREG | Amphiregulin. (210 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) | ||||
CEBPB | CCAAT/enhancer-binding protein beta; Important transcriptional activator regulating the expression of genes involved in immune and inflammatory responses. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'- T[TG]NNGNAA[TG]-3'. Functions in brown adipose tissue (BAT) differentiation. Regulates the transcriptional induction of peroxisome proliferator-activated receptor gamma (PPARG). Binds to the MGF and MIM-1 promoters and activates [...] (328 aa) | ||||
EHF | Uncharacterized protein. (298 aa) | ||||
DRD2 | Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa) | ||||
PROK2 | Prokineticin 2. (109 aa) | ||||
APOA1 | Proapolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT); Belongs to the apolipoprotein A1/A4/E family. (264 aa) | ||||
A4GNT | Alpha-1,4-N-acetylglucosaminyltransferase. (388 aa) | ||||
XBP1 | BZIP domain-containing protein. (372 aa) | ||||
SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (503 aa) | ||||
HNF1B | HNF1 homeobox B. (531 aa) | ||||
PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa) | ||||
NKX2-5 | Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Binds to the core DNA motif of promoter. Belongs to the NK-2 homeobox family. (294 aa) | ||||
MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) | ||||
KDF1 | Keratinocyte differentiation factor 1. (417 aa) | ||||
LOXL2 | Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (773 aa) | ||||
SAV1 | Salvador family WW domain containing protein 1. (385 aa) | ||||
TRIM24 | Tripartite motif containing 24. (1165 aa) | ||||
ST8SIA1 | CMP-NeuAc:GM3 sialyltransferase; Belongs to the glycosyltransferase 29 family. (342 aa) | ||||
KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1348 aa) | ||||
IFT57 | Intraflagellar transport 57. (532 aa) | ||||
ITGB1BP1 | PID domain-containing protein. (208 aa) | ||||
IFT172 | Intraflagellar transport 172. (1749 aa) | ||||
C26H6orf89 | Uncharacterized protein. (328 aa) | ||||
ERD2L | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (305 aa) | ||||
PHOX2B | Paired like homeobox 2B. (292 aa) | ||||
IGFBP5 | Insulin like growth factor binding protein 5. (269 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa) | ||||
TGFA | EGF-like domain-containing protein. (156 aa) | ||||
TNFSF11 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (400 aa) | ||||
NKX2-8 | NK2 homeobox 8. (203 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
CAV1 | Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa) | ||||
ENSGALP00000044025 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (617 aa) | ||||
IFT52 | Uncharacterized protein. (489 aa) | ||||
MTSS1 | Uncharacterized protein. (701 aa) | ||||
CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (487 aa) | ||||
AR | Uncharacterized protein. (703 aa) | ||||
NOX5 | Uncharacterized protein. (771 aa) | ||||
CCN3 | CCN family member 3; Immediate-early protein likely to play a role in cell growth regulation. Its overexpression is associated with tumorigenesis and expression of a N-terminal-truncated version of CCN3 gene in chicken embryonic fibroblasts (CEF) is sufficient to induce the transformation of CEF in vitro. (351 aa) | ||||
FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) | ||||
BTRC | Beta-transducin repeat containing E3 ubiquitin protein ligase. (793 aa) | ||||
SMO | Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). (816 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa) | ||||
LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (952 aa) | ||||
WDR77 | WD_REPEATS_REGION domain-containing protein. (359 aa) | ||||
BMPER | Crossveinless-2. (678 aa) | ||||
BCL2L1 | Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity). (229 aa) | ||||
TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) | ||||
PDX1 | Homeobox domain-containing protein. (259 aa) | ||||
WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (507 aa) | ||||
PRKX | Uncharacterized protein; Belongs to the protein kinase superfamily. (366 aa) | ||||
BAK1 | Uncharacterized protein. (216 aa) | ||||
ESRP2 | Epithelial splicing regulatory protein 2; mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2 (By similarity); Belongs to the ESRP family. (728 aa) | ||||
SERPINF1 | SERPIN domain-containing protein; Belongs to the serpin family. (416 aa) | ||||
EPHA2 | EPH receptor A2. (1288 aa) | ||||
HLX | H2.0 like homeobox. (431 aa) | ||||
BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa) | ||||
TP63 | Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa) | ||||
CAV2 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa) | ||||
NRARP | NOTCH regulated ankyrin repeat protein. (124 aa) | ||||
NCSTN | Ncstrn_small domain-containing protein. (717 aa) | ||||
SDR16C5 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (476 aa) | ||||
PPARD | Uncharacterized protein. (545 aa) | ||||
TEK | TEK receptor tyrosine kinase. (1128 aa) | ||||
RB1 | Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Acts as a transcription repressor of E2F1 target genes. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV39H1, KMT5B and KMT5C, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Also acts as a transcription repressor of E2F target genes by recruiting c [...] (984 aa) | ||||
IGFBP4 | IGFBP N-terminal domain-containing protein. (284 aa) | ||||
PROK1 | Prokineticin 1. (99 aa) | ||||
PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) | ||||
FGL1 | Fibrinogen C-terminal domain-containing protein. (313 aa) | ||||
IFT74 | Intraflagellar transport 74. (591 aa) | ||||
IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response (By similarity). Belongs to the IL-6 superfamily. (307 aa) | ||||
EFNB2 | Ephrin-B2; Belongs to the ephrin family. (333 aa) | ||||
LOXL3 | Lysyl oxidase like 3. (755 aa) | ||||
IFT80 | Intraflagellar transport 80. (790 aa) |