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| | SNX4 | Sorting nexin 4. (435 aa) |
| | CASP6 | Uncharacterized protein; Belongs to the peptidase C14A family. (317 aa) |
| | POLR3B | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1132 aa) |
| | BCL2 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa) |
| | C3AR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (461 aa) |
| | IKBKE | Inhibitor of nuclear factor kappa B kinase subunit epsilon. (837 aa) |
| | TEC | Tyrosine-protein kinase. (630 aa) |
| | TXK | Protein kinase domain-containing protein. (162 aa) |
| | KMT5B | Lysine methyltransferase 5B. (857 aa) |
| | PLA2G5 | Phospholipase A(2). (158 aa) |
| | C1S | Uncharacterized protein; Belongs to the peptidase S1 family. (701 aa) |
| | C1R | Complement C1r; Belongs to the peptidase S1 family. (712 aa) |
| | IL6ST | Glycoprotein 130. (918 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (262 aa) |
| | C7 | Uncharacterized protein. (834 aa) |
| | RIOK3 | Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (516 aa) |
| | CD274 | Uncharacterized protein. (471 aa) |
| | SYK | Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can a [...] (636 aa) |
| | TOMM70 | Translocase of outer mitochondrial membrane 70. (583 aa) |
| | NFKBIZ | ANK_REP_REGION domain-containing protein. (618 aa) |
| | CD247 | Uncharacterized protein. (166 aa) |
| | WHSC1-2 | Uncharacterized protein. (592 aa) |
| | AKIRIN2 | Akirin. (191 aa) |
| | CGAS | Cyclic GMP-AMP synthase. (294 aa) |
| | RSAD2 | Viperin. (354 aa) |
| | BLK | Tyrosine-protein kinase. (526 aa) |
| | IL17F | Uncharacterized protein. (169 aa) |
| | IL17A | Uncharacterized protein. (169 aa) |
| | TNFRSF21 | Uncharacterized protein. (651 aa) |
| | IL18RAP | Interleukin 18 receptor accessory protein. (652 aa) |
| | TNFSF13B | TNF family B cell activation factor; Belongs to the tumor necrosis factor family. (288 aa) |
| | ACOD1 | Uncharacterized protein. (478 aa) |
| | RGCC | Regulator of cell cycle. (135 aa) |
| | RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | ADORA2B | Adenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (340 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (412 aa) |
| | ANXA1 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing (By similarity). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contribut [...] (342 aa) |
| | LOC101751887 | ANK_REP_REGION domain-containing protein. (178 aa) |
| | PSPC1 | Paraspeckle component 1; Together with NONO, required for the formation of nuclear paraspeckles. Acts as a coactivator during transcriptional activation. Binds to RNA. May act as a regulator the circadian clock (By similarity); Belongs to the PSPC family. (523 aa) |
| | TRAT1 | T cell receptor associated transmembrane adaptor 1. (175 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (711 aa) |
| | RIF1 | Telomere-associated protein RIF1; Key regulator of TP53BP1 that plays a key role in the repair of double-strand DNA breaks (DSBs) in response to DNA damage: acts by promoting non-homologous end joining (NHEJ)-mediated repair of DSBs. In response to DNA damage, interacts with ATM- phosphorylated TP53BP1, allowing recruitment to DNA DSBs (By similarity). Once recruited to DSBs, RIF1 and TP53BP1 act by promoting NHEJ-mediated repair of DSBs. In the same time, RIF1 and TP53BP1 specifically counteract DSBs resection via homologous recombination (HR) during G1 phase (By similarity). (2168 aa) |
| | CD40 | Uncharacterized protein. (299 aa) |
| | CMTM3 | BASH/BLNK N-terminal associated protein 2. (169 aa) |
| | THY1 | Thy-1 membrane glycoprotein; May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. (161 aa) |
| | MBL2 | Mannose-binding protein; Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. (254 aa) |
| | DMB1 | Ig-like domain-containing protein. (310 aa) |
| | SHLD2 | Shieldin complex subunit 2. (895 aa) |
| | TRIM62 | Tripartite motif containing 62. (751 aa) |
| | SH2D1B | SH2 domain-containing protein. (134 aa) |
| | THEMIS2 | Thymocyte selection associated family member 2. (576 aa) |
| | CATH1 | Cathelicidin-1; Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response. (148 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (671 aa) |
| | FGR | Proto-oncogene tyrosine-protein kinase Yrk; May participate in signaling pathways; Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (536 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7. (643 aa) |
| | ENSGALP00000044025 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (617 aa) |
| | LOC107055217 | Ig-like domain-containing protein. (228 aa) |
| | ENSGALP00000044374 | Uncharacterized protein. (341 aa) |
| | VAV2 | Uncharacterized protein. (844 aa) |
| | CADM1 | Cell adhesion molecule 1. (437 aa) |
| | ENSGALP00000045895 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (363 aa) |
| | MLH1 | DNA mismatch repair protein MLH1. (757 aa) |
| | THEMIS | Thymocyte selection associated. (776 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (905 aa) |
| | FCN2 | Fibrinogen C-terminal domain-containing protein. (399 aa) |
| | MALT1 | MALT1 paracaspase. (816 aa) |
| | LAT2 | Linker for activation of T-cells family member 2; Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells. May also be involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization through the recruitment of GRB2. (198 aa) |
| | SHLD3 | Shieldin complex subunit 3. (249 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (574 aa) |
| | FBXO38 | F-box protein 38. (1186 aa) |
| | LYN | Tyrosine-protein kinase. (491 aa) |
| | TP53BP1 | Tumor protein p53 binding protein 1. (1907 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (681 aa) |
| | MYB | Transcriptional activator Myb; Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. (785 aa) |
| | C4 | Uncharacterized protein. (1705 aa) |
| | POLR3D | Uncharacterized protein. (753 aa) |
| | CCR7 | C-C chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa) |
| | PARK7 | Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] (189 aa) |
| | TMEM173 | Stimulator of interferon genes protein; Facilitator of innate immune signaling that acts as a sensor of cytosolic DNA from bacteria and viruses and promotes the production of type I interferon (IFN-alpha and IFN-beta) (By similarity). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm (By similarity). Acts by binding cyclic dinucleotides: recognizes and binds cyclic di- GMP (c-di-GMP), a second messenger produced by bacteria, and cyclic GMP-AMP (cGAMP), a messenger produced by CGAS in response to DNA virus [...] (379 aa) |
| | EIF2B4 | Eukaryotic translation initiation factor 2B subunit delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (330 aa) |
| | SFPQ | Splicing factor proline and glutamine rich. (647 aa) |
| | C3 | Uncharacterized protein. (1794 aa) |
| | IL1B | Interleukin-1; Belongs to the IL-1 family. (267 aa) |
| | C5 | Complement C5. (1758 aa) |
| | CACNB4 | SH3 domain-containing protein. (480 aa) |
| | C8G | Complement C8 gamma chain; Belongs to the calycin superfamily. Lipocalin family. (201 aa) |
| | NLRC5 | NACHT domain-containing protein. (1862 aa) |
| | C1QC | Complement C1q C chain. (245 aa) |
| | RBM14 | RNA binding motif protein 14. (750 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa) |
| | IFNL3A | Interferon lambda-3; Cytokine which plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specif [...] (186 aa) |
| | EIF2B5 | Eukaryotic translation initiation factor 2B subunit epsilon. (711 aa) |
| | LAMP1 | Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis; Belongs to the LAMP family. (406 aa) |
| | KHDRBS1 | KH domain-containing, RNA-binding, signal transduction-associated protein 1; Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates [...] (442 aa) |
| | PCASP3 | Uncharacterized protein. (632 aa) |
| | IL4R | Fibronectin type-III domain-containing protein. (996 aa) |
| | VAV3 | GDP/GTP exchange factor VAV3. (846 aa) |
| | PTPRC | Uncharacterized protein. (1237 aa) |
| | CD55 | Uncharacterized protein. (302 aa) |
| | C4A | Uncharacterized protein. (1687 aa) |
| | ENSGALP00000056976 | PH domain-containing protein. (114 aa) |
| | PCASP2 | Uncharacterized protein. (741 aa) |
| | TESPA1 | KRAP_IP3R_bind domain-containing protein. (600 aa) |
| | HLX | H2.0 like homeobox. (431 aa) |
| | SASH3 | Uncharacterized protein. (382 aa) |
| | DMB2 | Ig-like domain-containing protein. (323 aa) |
| | UBE2K | Uncharacterized protein; Belongs to the ubiquitin-conjugating enzyme family. (201 aa) |
| | LOC107051192 | RanBP2-type domain-containing protein. (1255 aa) |
| | ENSGALP00000060655 | Ig-like domain-containing protein. (186 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (480 aa) |
| | CXorf21 | Chromosome X open reading frame 21. (289 aa) |
| | C1QB | Complement C1q B chain. (244 aa) |
| | TIRAP | TIR domain-containing protein. (231 aa) |
| | ENSGALP00000062392 | Ig-like domain-containing protein. (297 aa) |
| | K4LB56_CHICK | CD150. (333 aa) |
| | NMI | N-myc and STAT interactor. (381 aa) |
| | FYB2 | FYN binding protein 2. (676 aa) |
| | MATR3 | Nuclear protein matrin 3. (902 aa) |
| | CD74 | Invariant chain isoform p41. (286 aa) |
| | LOC112532795 | Interferon lambda-3-like. (186 aa) |
| | DENND1B | DENN domain containing 1B. (794 aa) |
| | ENSGALP00000065128 | SH2 domain-containing protein. (126 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (324 aa) |
| | CLCF1 | Cardiotrophin like cytokine factor 1. (356 aa) |
| | POLR3C | RNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (459 aa) |
| | ENSGALP00000065797 | Reverse transcriptase domain-containing protein. (499 aa) |
| | ENSGALP00000065823 | Ig-like domain-containing protein. (163 aa) |
| | ENSGALP00000065835 | Calponin-homology (CH) domain-containing protein. (78 aa) |
| | SHLD1 | Shieldin complex subunit 1. (240 aa) |
| | ENSGALP00000065922 | Reverse transcriptase domain-containing protein. (411 aa) |
| | ENSGALP00000065981 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (164 aa) |
| | C5AR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | IL12RB1 | Fibronectin type-III domain-containing protein. (591 aa) |
| | COLEC11 | Collectin-11; Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis [...] (271 aa) |
| | ENSGALP00000066177 | Reverse transcriptase domain-containing protein. (598 aa) |
| | WHSC1 | Uncharacterized protein. (537 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (364 aa) |
| | IFNL3 | Interferon lambda 3. (186 aa) |
| | MORN5 | Uncharacterized protein. (297 aa) |
| | ENSGALP00000066996 | Uncharacterized protein. (110 aa) |
| | ENSGALP00000067084 | Reverse transcriptase domain-containing protein. (440 aa) |
| | EXOSC3 | KH_dom_type_1 domain-containing protein. (288 aa) |
| | ENSGALP00000067765 | Ig-like domain-containing protein. (242 aa) |
| | LOC112530289 | Uncharacterized protein. (398 aa) |
| | ENSGALP00000068109 | Ig-like domain-containing protein. (123 aa) |
| | FFAR2L | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (367 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (545 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (711 aa) |
| | BMX | Tyrosine-protein kinase. (630 aa) |
| | RNF5 | E3 ubiquitin-protein ligase RNF185; E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination. Acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and [...] (229 aa) |
| | ARID5A | AT-rich interaction domain 5A. (618 aa) |
| | GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) |
| | ENSGALP00000069011 | Reverse transcriptase domain-containing protein. (383 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (187 aa) |
| | ENSGALP00000069370 | Reverse transcriptase domain-containing protein. (549 aa) |
| | ENSGALP00000069458 | Uncharacterized protein. (314 aa) |
| | ENSGALP00000069472 | Ig-like domain-containing protein. (160 aa) |
| | ENSGALP00000069499 | Ig-like domain-containing protein. (129 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (481 aa) |
| | COLEC10 | Collectin-10; Lectin that binds to various sugars: galactose > mannose = fucose > N-acetylglucosamine > N-acetylgalactosamine. Acts as a chemoattractant, probably involved in the regulation of cell migration. (277 aa) |
| | RC3H1 | Ring finger and CCCH-type domains 1. (1114 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) |
| | LOC107050658 | Free fatty acid receptor 2-like. (367 aa) |
| | FYN | Tyrosine-protein kinase Fyn; Tyrosine-protein kinase implicated in the control of cell growth. Plays a role in the regulation of intracellular calcium levels. Required in brain development and mature brain function with important roles in the regulation of axon growth, axon guidance, and neurite extension. Role in CNTN1-mediated signaling. (589 aa) |
| | ENSGALP00000070040 | SH3 domain-containing protein. (198 aa) |
| | TBX21 | T-box transcription factor 21. (580 aa) |
| | ENSGALP00000070208 | Reverse transcriptase domain-containing protein. (367 aa) |
| | ENSGALP00000070213 | Reverse transcriptase domain-containing protein. (594 aa) |
| | ENSGALP00000070246 | Reverse transcriptase domain-containing protein. (475 aa) |
| | ENSGALP00000070355 | Reverse transcriptase domain-containing protein. (951 aa) |
| | CMKLR1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (360 aa) |
| | ENSGALP00000070641 | Reverse transcriptase domain-containing protein. (354 aa) |
| | LOC776273 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1303 aa) |
| | ENSGALP00000071152 | Ig-like domain-containing protein. (235 aa) |
| | LOC769422 | Ig-like domain-containing protein. (250 aa) |
| | RIPK3 | Uncharacterized protein. (424 aa) |
| | ENSGALP00000071381 | Reverse transcriptase domain-containing protein. (571 aa) |
| | LOC770074 | Ig-like domain-containing protein. (242 aa) |
| | NFAM1 | Uncharacterized protein. (323 aa) |
| | ENSGALP00000071547 | Reverse transcriptase domain-containing protein. (335 aa) |
| | ENSGALP00000071809 | SH2 domain-containing protein. (217 aa) |
| | KMT5C | Lysine methyltransferase 5C. (449 aa) |
| | PRAM1 | hSH3 domain-containing protein. (546 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (355 aa) |
| | LSM14A | mRNA processing body assembly factor. (461 aa) |
| | ENSGALP00000072274 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (126 aa) |
| | ENSGALP00000072496 | Protein kinase domain-containing protein. (46 aa) |
| | CLNK | SH2 domain-containing protein. (175 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (856 aa) |
| | CD226 | CD226 molecule. (367 aa) |
| | ENSGALP00000072768 | Reverse transcriptase domain-containing protein. (445 aa) |
| | ENSGALP00000072897 | Reverse transcriptase domain-containing protein. (498 aa) |
| | HRAS | GTPase HRas, N-terminally processed; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. (189 aa) |
| | ENSGALP00000074268 | Reverse transcriptase domain-containing protein. (514 aa) |
| | ENSGALP00000073985 | Reverse transcriptase domain-containing protein. (557 aa) |
| | ENSGALP00000073719 | Reverse transcriptase domain-containing protein. (411 aa) |
| | ENSGALP00000073708 | Reverse transcriptase domain-containing protein. (944 aa) |
| | ENSGALP00000073531 | Reverse transcriptase domain-containing protein. (413 aa) |
| | LOC107057578 | Ig-like domain-containing protein. (228 aa) |
| | ENSGALP00000073439 | SH3 domain-containing protein. (144 aa) |
| | ENSGALP00000073333 | Ig-like domain-containing protein. (176 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (775 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (639 aa) |
| | CD79B | B29/Ig-b. (226 aa) |
| | LCK | Proto-oncogene tyrosine-protein kinase LCK; Tyrosine kinase that plays an essential role for the selection and maturation of developing T-cell in the thymus and in mature T-cell function. Is constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors and plays a key role in T-cell antigen receptor(TCR)-linked signal transduction pathways (By similarity); Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (508 aa) |
| | RAB29 | RAB29, member RAS oncogene family. (205 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (175 aa) |
| | KARS | Lysine--tRNA ligase. (590 aa) |
| | RC3H2 | Ring finger and CCCH-type domains 2. (1191 aa) |
| | IL12B | Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa) |
| | ZAP70 | Tyrosine-protein kinase. (609 aa) |
| | C1QBP | Complement C1q binding protein. (214 aa) |
| | MED1 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1583 aa) |
| | CD276 | Uncharacterized protein. (314 aa) |
| | CARD9 | Caspase recruitment domain family member 9. (574 aa) |
| | STOML2 | Stomatin like 2. (382 aa) |
| | LCP2 | SH2 domain-containing protein. (550 aa) |
| | KLHL6 | BTB domain-containing protein. (610 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (881 aa) |
| | IFI35 | Interferon induced protein 35. (379 aa) |
| | MASP2 | Uncharacterized protein; Belongs to the peptidase S1 family. (687 aa) |
| | EIF2B1 | Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (302 aa) |
| | ATAD5 | AAA domain-containing protein. (1816 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1277 aa) |
| | FYB | Uncharacterized protein. (836 aa) |
| | ITK | Protein kinase domain-containing protein. (183 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (574 aa) |
| | CARD11 | Uncharacterized protein. (1170 aa) |
| | C1QA | Complement C1q A chain. (243 aa) |
| | ZNFX1 | Zinc finger NFX1-type containing 1. (2027 aa) |
| | PLA2G4A | Cytosolic phospholipase A2; Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response. (789 aa) |
| | NONO | Uncharacterized protein. (473 aa) |
| | XBP1 | BZIP domain-containing protein. (372 aa) |
| | HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (336 aa) |
| | CRKL | CRK like proto-oncogene, adaptor protein. (193 aa) |
| | CRTAM | Uncharacterized protein. (439 aa) |
| | SPPL3 | Signal peptide peptidase like 3. (384 aa) |
| | SPG21 | AB hydrolase-1 domain-containing protein. (310 aa) |
| | SERPING1 | Calponin-homology (CH) domain-containing protein; Belongs to the serpin family. (776 aa) |
| | MASP1 | Uncharacterized protein; Belongs to the peptidase S1 family. (779 aa) |
| | TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Belongs to the peptidase M28 family. M28B subfamily. (776 aa) |
| | IRG1L | Uncharacterized protein. (463 aa) |
| | FADD | Fas associated via death domain. (195 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase, cytosolic [GTP]; Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate; Belongs to the phosphoenolpyruvate carboxykinase [...] (622 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (927 aa) |
| | HSPD1 | 60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...] (573 aa) |
| | SH2D1A | SH2 domain containing 1A. (124 aa) |
| | HRG | Uncharacterized protein. (1078 aa) |
| | CTLA4 | Cytotoxic T-lymphocyte-associated protein 4. (205 aa) |
| | CD28 | T-cell-specific surface glycoprotein CD28 homolog; Possibly involved in T-cell activation. (304 aa) |
| | POLR3F | DNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (314 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (942 aa) |
| | IL12A | Interleukin-12 subunit alpha; Belongs to the IL-6 superfamily. (203 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1656 aa) |
| | TBK1 | Protein kinase domain-containing protein. (729 aa) |
| | COCH | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. (546 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | EIF2B3 | NTP_transferase domain-containing protein. (479 aa) |
| | EIF2B2 | Uncharacterized protein; Belongs to the eIF-2B alpha/beta/delta subunits family. (553 aa) |
| | HMGB2 | High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner (By similarity). Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Involved in inflammatory response to antige [...] (207 aa) |
| | C8A | Complement C8 alpha chain. (603 aa) |
| | C8B | MACPF domain-containing protein. (584 aa) |
| | EREG | EGF-like domain-containing protein. (153 aa) |
| | RFTN1 | Raftlin; May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling; Belongs to the raftlin family. (602 aa) |
| | STAP1 | Signal transducing adaptor family member 1. (293 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (145 aa) |
| | CFI | Uncharacterized protein; Belongs to the peptidase S1 family. (596 aa) |
