STRINGSTRING
AQP1 AQP1 IL22RA1 IL22RA1 IL12B IL12B TUSC2 TUSC2 AvBD14 AvBD14 CATH3 CATH3 LOC419276 LOC419276 RPL30 RPL30 RARRES2 RARRES2 BPIFCB BPIFCB AvBD11 AvBD11 AvBD7 AvBD7 CAMP CAMP IL17A IL17A IL17F IL17F AvBD10 AvBD10 AvBD13 AvBD13 RSFR RSFR AvBD4 AvBD4 AvBD9 AvBD9 ROMO1 ROMO1 DROSHA DROSHA HMGB2 HMGB2 CATH1 CATH1 CATHB1 CATHB1 OVALX OVALX LYZ LYZ F2 F2 TLR4 TLR4 LBP LBP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AQP1Aquaporin-1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (592 aa)
IL12BInterleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (315 aa)
TUSC2Uncharacterized protein. (250 aa)
AvBD14Gallinacin-14; Has bactericidal activity; Belongs to the beta-defensin family. (64 aa)
CATH3Cathelicidin-3; May bind bacterial lipopolysaccharide (LPS). May have antimicrobial activity and play a role in the innate immune response (By similarity). (151 aa)
LOC419276Uncharacterized protein. (554 aa)
RPL3060S ribosomal protein L30; Belongs to the eukaryotic ribosomal protein eL30 family. (115 aa)
RARRES2Chemerin. (162 aa)
BPIFCBBPI fold containing family C. (469 aa)
AvBD11Gallinacin-11; Has bactericidal activity. (104 aa)
AvBD7Gallinacin-7; Has bactericidal activity. (67 aa)
CAMPCathelicidin-2; Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response. (154 aa)
IL17AUncharacterized protein. (169 aa)
IL17FUncharacterized protein. (169 aa)
AvBD10Gallinacin-10; Has bactericidal activity. (68 aa)
AvBD13Gallinacin-13; Has bactericidal activity. Potent activity against E.coli, L.monocytogenes, S.typhimurium and S.pyogenes but mot against S.aureus. (89 aa)
RSFRRibonuclease homolog. (139 aa)
AvBD4Gallinacin-4; Has bactericidal activity. Potent activity against S.typhimurium and S.entiriditis. (63 aa)
AvBD9Gallinacin-9; Has bactericidal activity. Potent activity against C.jejuni, C.perfringens, S.aureus, C.albicans and S.cerevisiae. Less potent against S.typhimurium and E.coli. (67 aa)
ROMO1Uncharacterized protein. (79 aa)
DROSHAUncharacterized protein. (1336 aa)
HMGB2High mobility group protein B2; Multifunctional protein with various roles in different cellular compartments. May act in a redox sensitive manner (By similarity). Associates with chromatin and binds DNA with a preference to non-canonical DNA structures such as single-stranded DNA. Can bent DNA and enhance DNA flexibility by looping thus providing a mechanism to promote activities on various gene promoters. Proposed to be involved in the innate immune response to nucleic acids by acting as a cytoplasmic promiscuous immunogenic DNA/RNA sensor. Involved in inflammatory response to antige [...] (207 aa)
CATH1Cathelicidin-1; Binds bacterial lipopolysaccharide (LPS). Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). Has hemolytic activity (in vitro). May play a role in the innate immune response. (148 aa)
CATHB1Cathelicidin-B1; Has potent antimicrobial activity against Gram-positive and Gram-negative bacteria (in vitro). May play a role in the innate immune response. (251 aa)
OVALXOvalbumin-related protein X; Belongs to the serpin family. Ov-serpin subfamily. (388 aa)
LYZLysozyme C; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus; Belongs to the glycosyl hydrolase 22 family. (147 aa)
F2Uncharacterized protein; Belongs to the peptidase S1 family. (644 aa)
TLR4Toll-like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
LBPUncharacterized protein. (481 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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