STRINGSTRING
SLC1A3 SLC1A3 AARS AARS LRRC45 LRRC45 ABL1 ABL1 GPR88 GPR88 PAFAH1B1 PAFAH1B1 USH1C USH1C CLRN1 CLRN1 PTPRQ PTPRQ BLOC1S4 BLOC1S4 HEXB HEXB APP APP ENSGALP00000074158 ENSGALP00000074158 IGDCC3 IGDCC3 GM2A GM2A USH1G USH1G CLN8 CLN8 TPP1 TPP1 POU4F1 POU4F1 NRXN1 NRXN1 ABL2 ABL2 ALDH1A3 ALDH1A3 GIGYF2 GIGYF2 HEXA HEXA NEFL NEFL REST REST RBFOX1 RBFOX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLC1A3Amino acid transporter. (543 aa)
AARSAA_TRNA_LIGASE_II_ALA domain-containing protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. (968 aa)
LRRC45Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion. (670 aa)
ABL1Tyrosine-protein kinase. (1111 aa)
GPR88G protein-coupled receptor 88. (336 aa)
PAFAH1B1Lissencephaly-1 homolog; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. May be required for proliferation of neuronal precursors and neuronal migration. (410 aa)
USH1CUSH1 protein network component harmonin. (556 aa)
CLRN1Clarin 1. (232 aa)
PTPRQProtein tyrosine phosphatase receptor type Q. (2308 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (214 aa)
HEXBBeta-hexosaminidase. (558 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (751 aa)
ENSGALP00000074158LAM_G_DOMAIN domain-containing protein. (326 aa)
IGDCC3Immunoglobulin superfamily DCC subclass member 3. (773 aa)
GM2AGM2 ganglioside activator. (118 aa)
USH1GUSH1 protein network component sans. (457 aa)
CLN8TLC domain-containing protein. (285 aa)
TPP1Tripeptidyl peptidase 1. (575 aa)
POU4F1POU domain, class 4, transcription factor 1; Multifunctional transcription factor with different regions mediating its different effects. Acts by binding (via its C-terminal domain) to sequences related to the consensus octamer motif 5'- ATGCAAAT-3' in the regulatory regions of its target genes. Regulates the expression of specific genes involved in differentiation and survival within a subset of neuronal lineages. It has been shown that activation of some of these genes requires its N-terminal domain, maybe through a neuronal-specific cofactor; Belongs to the POU transcription factor [...] (389 aa)
NRXN1Neurexin-1; Neuronal cell surface protein that may be involved in cell recognition and cell adhesion. May mediate intracellular signaling. (1503 aa)
ABL2Tyrosine-protein kinase. (1159 aa)
ALDH1A3Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (512 aa)
GIGYF2GYF domain-containing protein. (1278 aa)
HEXABeta-hexosaminidase. (631 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (373 aa)
RESTUncharacterized protein. (339 aa)
RBFOX1RNA binding protein fox-1 homolog 1; RNA-binding protein that regulates alternative splicing events. (418 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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