(7 nodes) G-quadruplex DNA binding network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WRN	Uncharacterized protein. (1622 aa)
	DHX36	DEAH-box helicase 36. (987 aa)
	LONP1	Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. ECO:0000256\|PROSITE-. (932 aa)
	RAD50	Zinc-hook domain-containing protein. (1313 aa)
	PIF1	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (617 aa)
	XRN1	5'-3' exoribonuclease 1. (1770 aa)
	DDX11	DEAD/H-box helicase 11. (908 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX11	DHX36	ENSGALP00000069088	ENSGALP00000052194	DEAD/H-box helicase 11.	DEAH-box helicase 36.	0.741
DDX11	PIF1	ENSGALP00000069088	ENSGALP00000014682	DEAD/H-box helicase 11.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.771
DDX11	WRN	ENSGALP00000069088	ENSGALP00000068726	DEAD/H-box helicase 11.	Uncharacterized protein.	0.667
DHX36	DDX11	ENSGALP00000052194	ENSGALP00000069088	DEAH-box helicase 36.	DEAD/H-box helicase 11.	0.741
DHX36	PIF1	ENSGALP00000052194	ENSGALP00000014682	DEAH-box helicase 36.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.593
DHX36	WRN	ENSGALP00000052194	ENSGALP00000068726	DEAH-box helicase 36.	Uncharacterized protein.	0.443
PIF1	DDX11	ENSGALP00000014682	ENSGALP00000069088	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DEAD/H-box helicase 11.	0.771
PIF1	DHX36	ENSGALP00000014682	ENSGALP00000052194	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	DEAH-box helicase 36.	0.593
PIF1	RAD50	ENSGALP00000014682	ENSGALP00000039135	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Zinc-hook domain-containing protein.	0.802
PIF1	WRN	ENSGALP00000014682	ENSGALP00000068726	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	Uncharacterized protein.	0.970
RAD50	PIF1	ENSGALP00000039135	ENSGALP00000014682	Zinc-hook domain-containing protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.802
RAD50	WRN	ENSGALP00000039135	ENSGALP00000068726	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.856
WRN	DDX11	ENSGALP00000068726	ENSGALP00000069088	Uncharacterized protein.	DEAD/H-box helicase 11.	0.667
WRN	DHX36	ENSGALP00000068726	ENSGALP00000052194	Uncharacterized protein.	DEAH-box helicase 36.	0.443
WRN	PIF1	ENSGALP00000068726	ENSGALP00000014682	Uncharacterized protein.	ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability.	0.970
WRN	RAD50	ENSGALP00000068726	ENSGALP00000039135	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.856