STRINGSTRING
PDLIM5 PDLIM5 ENSGALP00000073678 ENSGALP00000073678 MEF2A MEF2A ENSGALP00000070799 ENSGALP00000070799 LRRC10 LRRC10 ENSGALP00000068828 ENSGALP00000068828 ENSGALP00000068281 ENSGALP00000068281 ALPK2 ALPK2 NEBL1 NEBL1 ZMPSTE24 ZMPSTE24 LRRC10B LRRC10B TBX2 TBX2 SRF SRF ALPK3 ALPK3 ATG5 ATG5 MYH11 MYH11 PITX2 PITX2 TBX3 TBX3 MAP2K4 MAP2K4 ISL1 ISL1 TSTD1 TSTD1 LRRC40 LRRC40 ASB2 ASB2 PROX1 PROX1 NRAP NRAP AKAP13 AKAP13 CSRP3 CSRP3 MTOR MTOR NKX2-5 NKX2-5 ADRA1A ADRA1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDLIM5Uncharacterized protein. (623 aa)
ENSGALP00000073678Uncharacterized protein. (419 aa)
MEF2AMyocyte-specific enhancer factor 2A; Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Mediates cellular functions in skeletal and cardiac muscle development. (545 aa)
ENSGALP00000070799SH3 domain-containing protein. (249 aa)
LRRC10Leucine rich repeat containing 10. (248 aa)
ENSGALP00000068828Uncharacterized protein. (185 aa)
ENSGALP00000068281ANK_REP_REGION domain-containing protein. (213 aa)
ALPK2Uncharacterized protein. (1806 aa)
NEBL1Uncharacterized protein. (2613 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (465 aa)
LRRC10BLeucine rich repeat containing 10B. (269 aa)
TBX2T-box transcription factor 2. (693 aa)
SRFSerum response factor; SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Together with MRTFA transcription coactivator, controls expression of genes regulating the cytoskeleton during development, morphogenesis and cell migration. (492 aa)
ALPK3Alpha kinase 3. (1545 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
MYH11Myosin-11; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1978 aa)
PITX2Pituitary homeobox 2; May play an important role in development and maintenance of anterior structures. May play a role in determining left-right asymmetry and in vasculogenesis during avian embryogenesis. (333 aa)
TBX3T-box transcription factor TBX3; Transcriptional repressor involved in developmental processes. Probably plays a role in limb pattern formation. (732 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (426 aa)
ISL1Insulin gene enhancer protein ISL-1; Acts as a transcriptional regulator. Recognizes and binds to the consensus octamer binding site 5'-ATAATTAA- 3' in promoter of target genes. Plays a fundamental role in the gene regulatory network essential for retinal ganglion cell (RGC) differentiation. Binds to insulin gene enhancer sequences (By similarity). Defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with LHX1, LHX3 and ISL2. Binds to insulin gene enhancer sequences (By similarity). Essential for heart d [...] (349 aa)
TSTD1Uncharacterized protein. (358 aa)
LRRC40Leucine-rich repeat-containing protein 40. (603 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (645 aa)
PROX1Prospero homeobox protein 1; Transcription factor which may be involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. May be essential in the development and function of the eye. May play a role in the regulation of the circadian rhythm by repressing the expression of clock genes; Belongs to the Prospero homeodomain family. (736 aa)
NRAPNebulin related anchoring protein. (1736 aa)
AKAP13Uncharacterized protein. (1341 aa)
CSRP3Uncharacterized protein. (194 aa)
MTORSerine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2521 aa)
NKX2-5Homeobox protein Nkx-2.5; Implicated in commitment to and/or differentiation of the myocardial lineage. Binds to the core DNA motif of promoter. Belongs to the NK-2 homeobox family. (294 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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