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| | FGG | Fibrinogen C-terminal domain-containing protein. (438 aa) |
| | FGA | Fibrinogen alpha chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. (741 aa) |
| | VWA2 | Von Willebrand factor A domain containing 2. (788 aa) |
| | F2 | Uncharacterized protein; Belongs to the peptidase S1 family. (644 aa) |
| | FGL2 | Fibrinogen C-terminal domain-containing protein. (439 aa) |
| | LAMB1 | Laminin subunit beta-1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. (1785 aa) |
| | KAZALD1 | Kazal type serine peptidase inhibitor domain 1. (296 aa) |
| | COL24A1 | Fibrillar collagen NC1 domain-containing protein. (1688 aa) |
| | GPC2 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (618 aa) |
| | NTN4L | Uncharacterized protein. (638 aa) |
| | RBP3 | Uncharacterized protein. (1235 aa) |
| | COL20A1 | Uncharacterized protein. (1472 aa) |
| | FREM1 | FRAS1 related extracellular matrix 1. (2184 aa) |
| | SERPINE2 | SERPIN domain-containing protein; Belongs to the serpin family. (442 aa) |
| | FBLN2 | Fibulin 2. (1196 aa) |
| | FBN1 | Fibrillin 1. (2861 aa) |
| | ECM2 | Extracellular matrix protein 2. (704 aa) |
| | SPARC | SPARC; Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity (By similarity). (298 aa) |
| | THSD4 | Thrombospondin type 1 domain containing 4. (1026 aa) |
| | MATN4 | Matrilin 4. (605 aa) |
| | FIBCD1 | Fibrinogen C domain containing 1. (556 aa) |
| | EGFLAM | EGF like, fibronectin type III and laminin G domains. (1026 aa) |
| | NTNG2 | Netrin G2. (527 aa) |
| | VTN | SMB domain-containing protein. (453 aa) |
| | MMP2 | 72 kDa type IV collagenase; Belongs to the peptidase M10A family. (663 aa) |
| | FN1 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa) |
| | COMP | Uncharacterized protein. (777 aa) |
| | MMRN2-2 | C1q domain-containing protein. (582 aa) |
| | VWA1 | Von Willebrand factor A domain containing 1. (499 aa) |
| | ADAMTS15 | ADAM metallopeptidase with thrombospondin type 1 motif 15. (931 aa) |
| | LAMB3 | Laminin subunit beta 3. (1168 aa) |
| | ANGPTL2 | Fibrinogen C-terminal domain-containing protein. (490 aa) |
| | ANGPTL4 | Angiopoietin like 4. (478 aa) |
| | LOXL2 | Lysyl oxidase homolog 2; Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). Acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Shows no activity against histone H3 when it is trimethylated on 'Lys- 9' (H3K9me3) or 'Lys-27' (H3K27me3) or when 'Lys-4' is monomethylated (H3K4me1) or dimethylated (H3K4me2). Also mediates deamination of methylated TAF10, a member o [...] (773 aa) |
| | ANGPTL1 | Fibrinogen C-terminal domain-containing protein. (530 aa) |
| | ENSGALP00000073838 | EGF-like domain-containing protein. (269 aa) |
| | LAMA5 | Laminin subunit alpha 5. (3725 aa) |
| | LOC101750972 | Peptidase S72 domain-containing protein. (1177 aa) |
| | THBS2 | Thrombospondin-2; Adhesive glycoprotein that mediates cell-to-cell and cell-to- matrix interactions; Belongs to the thrombospondin family. (1213 aa) |
| | NAV2 | Neuron navigator 2. (2452 aa) |
| | TINAGL1 | Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (473 aa) |
| | EMILIN1 | EMI domain-containing protein. (610 aa) |
| | SMOC2 | SPARC related modular calcium binding 2. (441 aa) |
| | TECTA | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane. The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. (2158 aa) |
| | ENSGALP00000071836 | Uncharacterized protein. (558 aa) |
| | FAM107B | Family with sequence similarity 107 member B. (334 aa) |
| | ABI3BP | Fibronectin type-III domain-containing protein. (511 aa) |
| | COL5A2 | Collagen type V alpha 2 chain. (1496 aa) |
| | LAMC3 | Uncharacterized protein. (332 aa) |
| | NTN3 | Netrin-3; Netrins control guidance of CNS commissural axons and peripheral motor axons. (644 aa) |
| | COL6A3 | Collagen alpha-3(VI) chain; Collagen VI acts as a cell-binding protein. (3215 aa) |
| | ENSGALP00000071129 | Uncharacterized protein. (332 aa) |
| | COL6A6 | Uncharacterized protein. (774 aa) |
| | PRG4 | Uncharacterized protein. (370 aa) |
| | TNN | Tenascin N. (1125 aa) |
| | ENSGALP00000069758 | Uncharacterized protein. (176 aa) |
| | LTBP1 | Uncharacterized protein. (1656 aa) |
| | ENSGALP00000069344 | Uncharacterized protein. (176 aa) |
| | ELN | Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. (811 aa) |
| | ENSGALP00000069232 | Uncharacterized protein. (626 aa) |
| | FGL1 | Fibrinogen C-terminal domain-containing protein. (313 aa) |
| | COL25A1-2 | Uncharacterized protein. (188 aa) |
| | LTBP2 | Latent transforming growth factor beta binding protein 2. (1851 aa) |
| | LAD1 | Uncharacterized protein. (454 aa) |
| | ENSGALP00000068108 | Uncharacterized protein. (589 aa) |
| | COL13A1-2 | Uncharacterized protein. (239 aa) |
| | ENSGALP00000067567 | Laminin IV type B domain-containing protein. (312 aa) |
| | LOXL3 | Lysyl oxidase like 3. (755 aa) |
| | LAMB4 | Uncharacterized protein. (1831 aa) |
| | LOXL1 | Protein-lysine 6-oxidase, short form; Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin; Belongs to the lysyl oxidase family. (511 aa) |
| | ENSGALP00000066764 | Fibronectin type-III domain-containing protein. (334 aa) |
| | ENSGALP00000066520 | Uncharacterized protein. (411 aa) |
| | ENSGALP00000066134 | Laminin N-terminal domain-containing protein. (533 aa) |
| | POSTN | Uncharacterized protein. (857 aa) |
| | LAMA2 | Uncharacterized protein. (598 aa) |
| | ENSGALP00000065673 | Uncharacterized protein. (899 aa) |
| | MEGF9 | Multiple EGF like domains 9. (219 aa) |
| | ENSGALP00000065397 | Uncharacterized protein. (113 aa) |
| | NID2 | Uncharacterized protein. (1170 aa) |
| | ANGPT2 | Angiopoietin-2A. (493 aa) |
| | ENSGALP00000064934 | Uncharacterized protein. (2030 aa) |
| | ENSGALP00000064853 | Uncharacterized protein. (165 aa) |
| | MATN2 | Matrilin 2. (1297 aa) |
| | ANGPTL3 | Fibrinogen C-terminal domain-containing protein. (464 aa) |
| | ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity). (262 aa) |
| | TNR | Tenascin-R; Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. Involved in cell attachment and neurite formation. Interaction with CNTN1 enhances the neurite outgrowth. (1353 aa) |
| | SPARCL1 | SPARC like 1. (658 aa) |
| | ENTPD2 | Ectonucleoside triphosphate diphosphohydrolase 2; In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent (By similarity). (536 aa) |
| | BCAN | Brevican. (968 aa) |
| | COL12A1 | Collagen alpha-1(XII) chain; Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix. (3122 aa) |
| | MDK | Midkine; Has mitogenic activity, and neurite extension activity for PC12 cells; Belongs to the pleiotrophin family. (239 aa) |
| | COL11A1 | Fibrillar collagen NC1 domain-containing protein. (888 aa) |
| | AGRN | Agrin C-terminal 110 kDa subunit; [Isoform 1]: heparan sulfate basal lamina glycoprotein that plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ) and directs key events in postsynaptic differentiation. Component of the AGRN-LRP4 receptor complex that induces the phosphorylation and activation of MUSK. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane. Calcium ions are required for maximal AChR clu [...] (2076 aa) |
| | MMRN2 | EMI domain-containing protein. (208 aa) |
| | ANGPT4 | Angiopoietin 4. (493 aa) |
| | TNC | Tenascin; Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6. (2130 aa) |
| | COL1A1 | Collagen alpha-1(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). (1453 aa) |
| | COL6A1 | Collagen alpha-1(VI) chain; Collagen VI acts as a cell-binding protein; Belongs to the type VI collagen family. (1019 aa) |
| | COL9A3 | Collagen alpha-3(IX) chain; Collagen type IX is a minor cartilage non-fibrillar collagen. It is associated with type II collagen fibrils; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. (675 aa) |
| | ENSGALP00000057063 | LAM_G_DOMAIN domain-containing protein. (263 aa) |
| | MATN1 | Cartilage matrix protein; Cartilage matrix protein is a major component of the extracellular matrix of non-articular cartilage. It binds to collagen. (493 aa) |
| | ENSGALP00000057014 | Uncharacterized protein. (511 aa) |
| | ADAMTS8 | ADAM metallopeptidase with thrombospondin type 1 motif 8. (903 aa) |
| | CILP | Cartilage intermediate layer protein. (1104 aa) |
| | RARRES2 | Chemerin. (162 aa) |
| | FBN2 | Fibrillin 2. (2903 aa) |
| | PTPRZ1 | Protein-tyrosine-phosphatase. (2343 aa) |
| | COLQ | Collagen like tail subunit of asymmetric acetylcholinesterase. (298 aa) |
| | ANGPT1L | Fibrinogen-like protein 1-like protein; Shows a cytidine deaminase activity on 2'-deoxycytidine (in vitro), however shows no RNA editing activity (in vitro). (281 aa) |
| | COL4A3 | Collagen IV NC1 domain-containing protein. (440 aa) |
| | GPC4 | Glypican 4; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (561 aa) |
| | COL2A1 | Collagen alpha-1(II) chain; Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. (1420 aa) |
| | ENSGALP00000052829 | Uncharacterized protein. (384 aa) |
| | NID1 | Nidogen 1. (1153 aa) |
| | ENSGALP00000052482 | Fibrinogen C-terminal domain-containing protein. (238 aa) |
| | COL14A1 | Collagen alpha-1(XIV) chain; An adhesive role by integrating collagen bundles. It is probably associated with the surface of interstitial collagen fibrils via COL1. The COL2 domain may then serve as a rigid arm which sticks out from the fibril and protrudes the large N-terminal globular domain into the extracellular space, where it might interact with other matrix molecules or cell surface receptors. (1888 aa) |
| | DAG1 | Peptidase S72 domain-containing protein. (896 aa) |
| | HSPG2 | Heparan sulfate proteoglycan 2. (3948 aa) |
| | FREM2 | FRAS1 related extracellular matrix 2. (3168 aa) |
| | COL5A1 | Fibrillar collagen NC1 domain-containing protein. (1835 aa) |
| | C9H2ORF82 | Uncharacterized protein. (121 aa) |
| | ANGPT1 | Fibrinogen C-terminal domain-containing protein. (498 aa) |
| | PRELP | Proline and arginine rich end leucine rich repeat protein. (430 aa) |
| | PXDNL | Uncharacterized protein. (1406 aa) |
| | COL15A1 | LAM_G_DOMAIN domain-containing protein. (1134 aa) |
| | ANXA2P2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. (339 aa) |
| | CASK | Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (944 aa) |
| | GPC1 | Secreted glypican-1; Cell surface proteoglycan that bears heparan sulfate. Modulates Wnt-signaling pathway. (550 aa) |
| | LAMB2 | Uncharacterized protein. (1802 aa) |
| | EFEMP1 | EGF containing fibulin extracellular matrix protein 1. (451 aa) |
| | P3H2 | Prolyl 3-hydroxylase 2; Prolyl 3-hydroxylase that catalyzes the post-translational formation of 3-hydroxyproline on collagens (By similarity). Contributes to proline 3-hydroxylation of collagen COL4A1 and COL1A1 in tendons, the eye sclera and in the eye lens capsule (By similarity). Has high activity with the type IV collagen COL4A1, and lower activity with COL1A1. Catalyzes hydroxylation of the first Pro in Gly-Pro-Hyp sequences where Hyp is 4-hydroxyproline. Has no activity on substrates that lack 4-hydroxyproline in the third position (By similarity). (694 aa) |
| | FCN2 | Fibrinogen C-terminal domain-containing protein. (399 aa) |
| | NDP | CTCK domain-containing protein. (133 aa) |
| | GPC5 | Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (624 aa) |
| | ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif 1. (924 aa) |
| | FBN3 | Fibrillin 3. (3009 aa) |
| | NTNG1 | Netrin G1. (483 aa) |
| | COL17A1 | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. (1510 aa) |
| | ENSGALP00000043926 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (252 aa) |
| | FMOD | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (380 aa) |
| | LAMA3 | Laminin subunit alpha 3. (3448 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (711 aa) |
| | COL6A2 | Collagen alpha-2(VI) chain; Collagen VI acts as a cell-binding protein. (1022 aa) |
| | COL16A1 | Uncharacterized protein. (464 aa) |
| | DEF8 | Differentially expressed in FDCP 8 homolog. (494 aa) |
| | COL27A1 | Fibrillar collagen NC1 domain-containing protein. (1889 aa) |
| | TIMP3 | Metalloproteinase inhibitor 3; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli; Belongs to the protease inhibitor I35 (TIMP) family. (212 aa) |
| | PRNP | Major prion protein homolog; Its primary physiological function is unclear. Has cytoprotective activity against internal or environmental stresses. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its h [...] (273 aa) |
| | LAMC1 | Laminin subunit gamma 1. (1603 aa) |
| | NTN1 | Netrin-1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Promotes neurite outgrowth from commissural axons but acts as a chemorepellent for trochlear motor axons. These effects are mediated by distinct receptors. (688 aa) |
| | ZP2 | ZP domain-containing protein. (829 aa) |
| | FGB | Fibrinogen beta chain; Cleaved by the protease thrombin to yield monomers which, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. (488 aa) |
| | FRAS1 | Uncharacterized protein. (3989 aa) |
| | COL9A1 | Collagen alpha-1(IX) chain; Structural component of hyaline cartilage and vitreous of the eye; Belongs to the fibril-associated collagens with interrupted helices (FACIT) family. (920 aa) |
| | IMPG2 | Interphotoreceptor matrix proteoglycan 2; Chondroitin sulfate- and hyaluronan-binding proteoglycan involved in the organization of interphotoreceptor matrix. (1420 aa) |
| | LAMA1 | Uncharacterized protein. (3091 aa) |
| | MATN3 | Matrilin-3; Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks. (452 aa) |
| | ANGPTL5 | Fibrinogen C-terminal domain-containing protein. (390 aa) |
| | ANGPTL7 | Angiopoietin like 7. (347 aa) |
| | C18H17orf58 | NTR domain-containing protein. (381 aa) |
| | MYOC | Myocilin. (467 aa) |
| | ZP4 | Uncharacterized protein. (542 aa) |
| | TGFB2 | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] (412 aa) |
| | GPC6 | Uncharacterized protein; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (263 aa) |
| | EGFL6 | EGF like domain multiple 6. (370 aa) |
| | LINC00954 | ZP domain-containing protein. (911 aa) |
| | ZPAX | Zona pellucida protein. (837 aa) |
| | PXDN | Peroxidasin. (1611 aa) |
| | TINAG | SMB domain-containing protein; Belongs to the peptidase C1 family. (467 aa) |
| | IMPG1 | Interphotoreceptor matrix proteoglycan 1; May be involved in a novel system mediating adhesion between neural retina and retinal pigment epithelium. (928 aa) |
| | ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif 5. (877 aa) |
| | VCAN | Versican core protein; May play a role in intercellular signaling and in connecting cells with the extracellular matrix. May take part in the regulation of cell motility, growth and differentiation. Binds hyaluronic acid. (3559 aa) |
| | RBP4 | Purpurin; May be involved in the transport of retinol between the photoreceptors and the pigmented epithelium; Belongs to the calycin superfamily. Lipocalin family. (196 aa) |
| | COL8A1 | Collagen alpha-1(VIII) chain; Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity). (739 aa) |
| | CCDC80 | Coiled-coil domain-containing protein 80; Promotes cell adhesion and matrix assembly (By similarity). May play a role in eye formation. (958 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1827 aa) |
| | THBS4 | Uncharacterized protein. (953 aa) |
| | LOXL4 | Lysyl oxidase like 4. (761 aa) |
| | VWC2 | Von Willebrand factor C domain containing 2. (383 aa) |
| | CHADL | Uncharacterized protein. (733 aa) |
| | MGP | Matrix Gla protein; Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation; Belongs to the osteocalcin/matrix Gla protein family. (103 aa) |
| | NTN4 | Netrin 4. (626 aa) |
| | LUM | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (343 aa) |
| | FBLN5 | Uncharacterized protein. (444 aa) |
| | F1NSR4_CHICK | Uncharacterized protein. (375 aa) |
| | COL28A1 | Collagen type XXVIII alpha 1 chain. (1140 aa) |
| | VIT | Uncharacterized protein. (748 aa) |
| | MMRN1 | Multimerin 1. (1192 aa) |
| | COCH | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. (546 aa) |
| | USH2A | Usherin. (5190 aa) |
| | COL1A2 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen). (1363 aa) |
| | THBS1 | Uncharacterized protein. (1175 aa) |
| | SMOC1 | SPARC related modular calcium binding 1. (457 aa) |
