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| | HELLS | Helicase, lymphoid specific. (822 aa) |
| | SMYD3 | SET and MYND domain containing 3. (487 aa) |
| | HIST1H2B5L | Histone H2B; Belongs to the histone H2B family. (126 aa) |
| | HIST1H2B5 | Histone H2B 5; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | HIST1H3G | Histone cluster 1 H3 family member g. (136 aa) |
| | H1-8 | H1 histone family member O oocyte specific. (239 aa) |
| | NAP1L4 | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (403 aa) |
| | UBTF | Upstream binding transcription factor. (744 aa) |
| | HIST1H2B7 | Histone cluster 1, H2B-VII (similar to human histone cluster 1, class H2B, member N). (126 aa) |
| | HIST1H2BF | Histone cluster 1, H2bf. (126 aa) |
| | CENPX | Centromere protein X; DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP-dependent remodeling of DNA. Stabilizes FANCM. In complex with CENPS and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked rep [...] (115 aa) |
| | LOC100859629 | Histone H3.3-like. (136 aa) |
| | CHAF1B | Chromatin assembly factor 1 subunit B; Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Involved in rapid nucleosome formation during DNA replication (By similarity); Belongs to the WD repeat HIR1 family. (566 aa) |
| | HIST1H4B-6 | Histone cluster 1, H4-IV, germinal H4-like 2. (103 aa) |
| | KAT6B | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1842 aa) |
| | SET | Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family. (277 aa) |
| | CENPP | Centromere protein P; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. (287 aa) |
| | KNTC1 | Rod_C domain-containing protein. (398 aa) |
| | CENPV | GFA domain-containing protein. (207 aa) |
| | KAT6A | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2008 aa) |
| | TAF11 | TAFII28 domain-containing protein. (217 aa) |
| | DNAJC9 | J domain-containing protein. (260 aa) |
| | BDP1 | SANT domain-containing protein. (2183 aa) |
| | CDC45 | Cell division cycle 45. (566 aa) |
| | TAF12 | TFIID_20kDa domain-containing protein. (161 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (328 aa) |
| | DLGAP5 | DLG associated protein 5. (833 aa) |
| | TBPL2 | TATA box binding protein-like 2. (328 aa) |
| | HIST1H111L | Histone H1.11R; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (219 aa) |
| | HISTH1 | Histone H1; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (305 aa) |
| | BRF1 | BRF1 RNA polymerase III transcription initiation factor subunit. (681 aa) |
| | CENPC | Uncharacterized protein. (872 aa) |
| | NAP1L1 | Nucleosome assembly protein 1 like 1; Belongs to the nucleosome assembly protein (NAP) family. (393 aa) |
| | HP1BP3 | Heterochromatin protein 1-binding protein 3; Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. (559 aa) |
| | F1NFV8_CHICK | WSD domain-containing protein. (308 aa) |
| | ATRX | ATRX chromatin remodeler. (2420 aa) |
| | TAF3 | Transcription initiation factor TFIID subunit 3; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process (By similarity). (930 aa) |
| | SPTY2D1 | Protein SPT2 homolog; Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Binds DNA and histones and promotes nucleosome assembly (in vitro) (By similarity). Modulates RNA polymerase 1-mediated transcription. Required for optimal growth in the presence of the DNA damaging agents actinomycin D or mitomycin C (in vitro). Facilitates formation of tetrameric histone complexes c [...] (690 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (929 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Involved in chromatin-remodeling. Core component of the BAF (SWI/SNF) complex. This ATP-dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex) and may play a role in neural development (By similarity). (386 aa) |
| | DR1 | Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). (176 aa) |
| | HNF1B | HNF1 homeobox B. (531 aa) |
| | TAF4 | TATA-box binding protein associated factor 4. (1101 aa) |
| | HIST1H3H | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (136 aa) |
| | HIST1H2BO | Histone H2B 1/2/3/4/6; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | HIST1H2B7L2 | Histone cluster 1, H2B-VII-like 2 (similar to human histone cluster 1, class H2B, member N). (126 aa) |
| | CENPA | Histone H3-like centromeric protein A; Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes. Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well- ordered and rigid compared to nucleosomes containing histone H3. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By simil [...] (131 aa) |
| | HIST1H3A | Histone cluster 1 H3 family member a. (136 aa) |
| | TAF7 | TAFII55_N domain-containing protein. (353 aa) |
| | RAD51 | DNA repair protein RAD51 homolog 1; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. (339 aa) |
| | RAD51C | RAD51 paralog C. (360 aa) |
| | BAZ1A | Uncharacterized protein. (397 aa) |
| | GTF2H5 | General transcription factor IIH subunit 5; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFII [...] (71 aa) |
| | HIST1H103 | Histone H1.03; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (224 aa) |
| | RSF1 | Remodeling and spacing factor 1. (1392 aa) |
| | HIST2H3A | Histone cluster 2 H3 family member d. (136 aa) |
| | CHRAC1 | Chromatin accessibility complex subunit 1. (135 aa) |
| | TAF6L | TATA-box binding protein associated factor 6 like. (604 aa) |
| | H2AFY | Core histone macro-H2A.1; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. The presence of macro-H2A enhances the interaction of the histone octamer wi [...] (372 aa) |
| | HIST1H4B | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (943 aa) |
| | HIST1H4B-2 | Histone cluster 1, H4d. (103 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1322 aa) |
| | CENPT | Centromere protein T; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...] (649 aa) |
| | NASP | Nuclear autoantigenic sperm protein. (456 aa) |
| | H1-10 | H1 histone family member X. (215 aa) |
| | ENSGALP00000054050 | Uncharacterized protein. (171 aa) |
| | HIST1H4B-3 | Histone cluster 1, H4-IV, germinal H4-like 6 (similar to human histone cluster 1, class H4 genes). (103 aa) |
| | HJURP | Uncharacterized protein. (772 aa) |
| | TAF1C | TATA-box binding protein associated factor, RNA polymerase I subunit C. (878 aa) |
| | CENPW | Centromere protein W; Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres (By similarity). Part of a nucleosome-associated complex that binds specifically to histone H3-containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP [...] (76 aa) |
| | TAF8 | Transcription initiation factor TFIID subunit 8; Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. Mediates both basal and activator-dependent transcription (By similarity). (312 aa) |
| | ITGB3BP | Centromere protein R; Transcription coregulator that can have both coactivator and corepressor functions. Involved in the coactivation of nuclear receptors for retinoid X (RXRs) and thyroid hormone (TRs) in a ligand- dependent fashion. Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). (179 aa) |
| | CENPS | Centromere protein S; DNA-binding component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPX (MHF heterodimer), crucial cofactor for FANCM in both binding and ATP- dependent remodeling of DNA. Stabilizes FANCM. In complex with CENPX and FANCM (but not other FANC proteins), rapidly recruited to blocked forks and promotes gene conversion at blocked re [...] (139 aa) |
| | POLE3 | CBFD_NFYB_HMF domain-containing protein. (143 aa) |
| | CENPN | Centromere protein N; Probable component of a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation; Belongs to the CENP-N/CHL4 family. (352 aa) |
| | SOX9 | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa) |
| | OIP5 | Mis18 domain-containing protein. (213 aa) |
| | CENPH | Centromere protein H; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. Required for the localization of CENPC but not CENPA to the centromere. It however may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex; Belongs to the CENP-H/MCM16 family. (235 aa) |
| | H3F3C | Histone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa) |
| | BRF2 | BRF2 RNA polymerase III transcription initiation factor subunit. (415 aa) |
| | CENPO | Centromere protein O; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation (By similarity). Involved in kinetochore assembly and required for recovery from spindle damage; Belongs to the CENP-O/MCM21 family. (325 aa) |
| | MIS18A | MIS18 kinetochore protein A. (204 aa) |
| | CENPK | Centromere protein K; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. (362 aa) |
| | CDT1 | Chromatin licensing and DNA replication factor 1. (745 aa) |
| | GMNN | Uncharacterized protein. (224 aa) |
| | CENPE | Centromere protein E; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2228 aa) |
| | SHPRH | SNF2 histone linker PHD RING helicase. (1691 aa) |
| | CENPI | Centromere protein I; Component of the CENPA-HI complex, a centromeric complex involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. Required for the localization of CENPC but not CENPA to the centromere. It however may be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. (753 aa) |
| | HIST2H3A-2 | Histone H3.2-like. (136 aa) |
| | HIST1H110 | Histone H1.10; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (220 aa) |
| | LOC107053803 | Histone H2B 7; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | LOC415780 | TAFH domain-containing protein. (1024 aa) |
| | ENSGALP00000055994 | Histone H3; Belongs to the histone H3 family. (136 aa) |
| | PADI1 | Peptidylarginine deiminase type I. (661 aa) |
| | HIST1H2B8 | Histone H2B 8; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (126 aa) |
| | HIST1H101 | Histone H1.01; Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. (220 aa) |
| | H2BE1 | Histone H2B; Belongs to the histone H2B family. (118 aa) |
| | RRN3 | Uncharacterized protein. (619 aa) |
| | HIST1H46 | Histone cluster 1, H4-VI, germinal H4 (similar to human histone cluster 1, class H4 genes). (103 aa) |
| | GTF2A2 | Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (109 aa) |
| | CHAF1A | Chromatin assembly factor 1 subunit A; Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Involved in rapid nucleosome formation during DNA replication. (937 aa) |
| | GTF2B | General transcription factor IIB. (344 aa) |
| | TBP | TATA-box-binding protein; General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. (302 aa) |
| | POLR1E | RNA polymerase I subunit E. (445 aa) |
| | H2AFY2 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa) |
| | SIRT6 | Deacetylase sirtuin-type domain-containing protein. (378 aa) |
| | RAD52 | DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). (422 aa) |
| | TAF13 | Uncharacterized protein. (124 aa) |
| | H3F3B | H3 histone, family 3B. (136 aa) |
| | HIST1H4B-4 | Histone cluster 1, H4i. (103 aa) |
| | RHOGL-2 | Transcription initiation factor TFIID subunit. (1860 aa) |
| | HIST1H2B7L4 | Histone cluster 1,H2B-VII-like 4 (similar to human histone cluster 1, class H2B, member N). (126 aa) |
| | HIST1H4B-5 | Histone cluster 2, H4b. (103 aa) |
| | TAF6 | TATA-box binding protein associated factor 6. (721 aa) |
| | ENSGALP00000067477 | Uncharacterized protein. (178 aa) |
