STRINGSTRING
PRELID1 PRELID1 FADD FADD GPAM GPAM DOCK8 DOCK8 BCL2 BCL2 IL7R IL7R CD274 CD274 SLC46A2 SLC46A2 LGALS3 LGALS3 BCL11B BCL11B KIFAP3 KIFAP3 PDCD1 PDCD1 PTCRA PTCRA ENSGALP00000066325 ENSGALP00000066325
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PRELID1PRELI domain-containing protein 1, mitochondrial; Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. The TRIAP1:PRELID1 complex probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane (By similarity). May be involved in hematopoiesis during avian development. (215 aa)
FADDFas associated via death domain. (195 aa)
GPAMGlycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa)
DOCK8Dedicator of cytokinesis 8; Belongs to the DOCK family. (2036 aa)
BCL2Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa)
IL7RInterleukin-7 receptor alpha chain. (460 aa)
CD274Uncharacterized protein. (471 aa)
SLC46A2Solute carrier family 46 member 2. (453 aa)
LGALS3Galectin. (258 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (884 aa)
KIFAP3Kinesin associated protein 3. (793 aa)
PDCD1Ig-like domain-containing protein. (304 aa)
PTCRAUncharacterized protein. (169 aa)
ENSGALP00000066325Uncharacterized protein. (71 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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