(50 nodes) Protein localization to mitochondrion network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CHCHD4	CHCH domain-containing protein. (138 aa)
	DNAJC19	DnaJ heat shock protein family (Hsp40) member C19. (115 aa)
	COX18	Cytochrome c oxidase assembly factor COX18. (317 aa)
	FBXO7	F-box domain-containing protein. (526 aa)
	TIMM21	Translocase of inner mitochondrial membrane 21. (327 aa)
	SAMM50	POTRA domain-containing protein. (469 aa)
	TOMM70	Translocase of outer mitochondrial membrane 70. (583 aa)
	DNAJC15	J domain-containing protein. (148 aa)
	MIPEP	Mitochondrial intermediate peptidase. (795 aa)
	TOMM22	Translocase of outer mitochondrial membrane 22. (139 aa)
	IMMP1L	Mitochondrial inner membrane protease subunit. (166 aa)
	IMMP2L	Peptidase_S24 domain-containing protein. (175 aa)
	ROMO1	Uncharacterized protein. (79 aa)
	TIMM13	zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family. (101 aa)
	R4GGX6_CHICK	Uncharacterized protein. (55 aa)
	MAIP1	Matrix AAA peptidase interacting protein 1. (248 aa)
	GDAP1	Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (343 aa)
	PINK1	PTEN induced kinase 1. (364 aa)
	TOMM34	Uncharacterized protein. (507 aa)
	DNLZ	DNL-type zinc finger. (117 aa)
	PRKN	E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (488 aa)
	DNM1L	Uncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
	GRPEL2	GrpE like 2, mitochondrial. (149 aa)
	DDIT3	C/EBP-like protein. (155 aa)
	MGARP	Mitochondria localized glutamic acid rich protein. (244 aa)
	ENSGALP00000068754	Uncharacterized protein. (89 aa)
	TSPO	Uncharacterized protein. (516 aa)
	MTERF4	Uncharacterized protein. (131 aa)
	C3orf18	Chromosome 3 open reading frame 18. (156 aa)
	TRMT10B	SAM-dependent MTase TRM10-type domain-containing protein. (598 aa)
	TIMM50	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (230 aa)
	GRPEL1	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family. (237 aa)
	MFF	Mitochondrial fission factor. (252 aa)
	BCS1L	Uncharacterized protein; Belongs to the AAA ATPase family. (419 aa)
	TOMM7	Uncharacterized protein. (55 aa)
	TSPO2	Translocator protein 2. (190 aa)
	AGK	Acylglycerol kinase. (399 aa)
	TOMM40L	Translocase of outer mitochondrial membrane 40 like. (303 aa)
	HSPA4	Heat shock protein family A (Hsp70) member 4. (840 aa)
	TOMM20	Translocase of outer mitochondrial membrane 20. (146 aa)
	SAMD15	Uncharacterized protein. (98 aa)
	TIMM17B	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (166 aa)
	TIMM44	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. (451 aa)
	PMPCA	Uncharacterized protein; Belongs to the peptidase M16 family. (519 aa)
	TIMM23B	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (208 aa)
	AIFM1	Uncharacterized protein. (689 aa)
	TIMM22	Translocase of inner mitochondrial membrane 22. (190 aa)
	MFN2	Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (762 aa)
	HSPD1	60 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...] (573 aa)
	TIMM10	zf-Tim10_DDP domain-containing protein. (90 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGK	TIMM10	ENSGALP00000061860	ENSGALP00000007724	Acylglycerol kinase.	zf-Tim10_DDP domain-containing protein.	0.852
AGK	TIMM22	ENSGALP00000061860	ENSGALP00000006979	Acylglycerol kinase.	Translocase of inner mitochondrial membrane 22.	0.719
AGK	TIMM50	ENSGALP00000061860	ENSGALP00000065130	Acylglycerol kinase.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.424
BCS1L	COX18	ENSGALP00000064039	ENSGALP00000018970	Uncharacterized protein; Belongs to the AAA ATPase family.	Cytochrome c oxidase assembly factor COX18.	0.423
BCS1L	GRPEL1	ENSGALP00000064039	ENSGALP00000064381	Uncharacterized protein; Belongs to the AAA ATPase family.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.423
BCS1L	GRPEL2	ENSGALP00000064039	ENSGALP00000069779	Uncharacterized protein; Belongs to the AAA ATPase family.	GrpE like 2, mitochondrial.	0.403
BCS1L	SAMM50	ENSGALP00000064039	ENSGALP00000022917	Uncharacterized protein; Belongs to the AAA ATPase family.	POTRA domain-containing protein.	0.451
BCS1L	TIMM10	ENSGALP00000064039	ENSGALP00000007724	Uncharacterized protein; Belongs to the AAA ATPase family.	zf-Tim10_DDP domain-containing protein.	0.482
BCS1L	TIMM21	ENSGALP00000064039	ENSGALP00000022251	Uncharacterized protein; Belongs to the AAA ATPase family.	Translocase of inner mitochondrial membrane 21.	0.620
BCS1L	TIMM44	ENSGALP00000064039	ENSGALP00000000471	Uncharacterized protein; Belongs to the AAA ATPase family.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.439
BCS1L	TOMM40L	ENSGALP00000064039	ENSGALP00000055223	Uncharacterized protein; Belongs to the AAA ATPase family.	Translocase of outer mitochondrial membrane 40 like.	0.420
BCS1L	TOMM70	ENSGALP00000064039	ENSGALP00000024624	Uncharacterized protein; Belongs to the AAA ATPase family.	Translocase of outer mitochondrial membrane 70.	0.642
C3orf18	SAMD15	ENSGALP00000067495	ENSGALP00000053228	Chromosome 3 open reading frame 18.	Uncharacterized protein.	0.440
C3orf18	TIMM10	ENSGALP00000067495	ENSGALP00000007724	Chromosome 3 open reading frame 18.	zf-Tim10_DDP domain-containing protein.	0.543
C3orf18	TIMM17B	ENSGALP00000067495	ENSGALP00000000122	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM17; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.610
C3orf18	TIMM21	ENSGALP00000067495	ENSGALP00000022251	Chromosome 3 open reading frame 18.	Translocase of inner mitochondrial membrane 21.	0.453
C3orf18	TIMM23B	ENSGALP00000067495	ENSGALP00000003252	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM23; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.678
C3orf18	TIMM44	ENSGALP00000067495	ENSGALP00000000471	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family.	0.538
C3orf18	TIMM50	ENSGALP00000067495	ENSGALP00000065130	Chromosome 3 open reading frame 18.	Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.	0.430
C3orf18	TOMM22	ENSGALP00000067495	ENSGALP00000029965	Chromosome 3 open reading frame 18.	Translocase of outer mitochondrial membrane 22.	0.475