STRINGSTRING
SNRPD2 SNRPD2 SNRPE SNRPE RNF113B RNF113B SF3A2 SF3A2 SF3A3 SF3A3 PRPF38B PRPF38B SNIP1 SNIP1 SMU1 SMU1 SF3B3 SF3B3 PRPF8 PRPF8 LSM4 LSM4 PRPF6 PRPF6 SNRPD3 SNRPD3 SNRPA1 SNRPA1 SF3A1 SF3A1 SF3B1 SF3B1 PRPF4 PRPF4 CWC22 CWC22 LSM8 LSM8 PRPF38A PRPF38A SNU13 SNU13 PHF5A PHF5A SF3B4 SF3B4 SF3B6 SF3B6 WBP4 WBP4 MFAP1 MFAP1 BUD13 BUD13 SNRPN SNRPN SF3B5 SF3B5 LSM3 LSM3 SNRPD1 SNRPD1 SNRNP200 SNRNP200 ZMAT2 ZMAT2 LSM5 LSM5 SNRPF SNRPF LSM6 LSM6 CWC27 CWC27 EFTUD2 EFTUD2 TXNL4A TXNL4A ENSGALP00000066377 ENSGALP00000066377 SNRPGP15 SNRPGP15 RBMX2 RBMX2 LOC112530170 LOC112530170
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SNRPD2Small nuclear ribonucleoprotein Sm D2. (146 aa)
SNRPESmall nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa)
RNF113BZinc finger protein 183. (328 aa)
SF3A2Splicing factor 3a subunit 2. (315 aa)
SF3A3Splicing factor 3a subunit 3. (501 aa)
PRPF38BUncharacterized protein. (549 aa)
SNIP1Smad nuclear interacting protein 1. (364 aa)
SMU1WD40 repeat-containing protein SMU1; Involved in pre-mRNA splicing as a component of the spliceosome (By similarity). Regulates alternative splicing of the HSPG2 pre-mRNA (By similarity). Required for normal accumulation of IK (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis (By similarity). Belongs to the WD repeat SMU1 family. (513 aa)
SF3B3Splicing factor 3b subunit 3. (1217 aa)
PRPF8Pre-mRNA processing factor 8. (2335 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (138 aa)
PRPF6Pre-mRNA processing factor 6. (941 aa)
SNRPD3Small nuclear ribonucleoprotein Sm D3. (126 aa)
SNRPA1LRRcap domain-containing protein. (255 aa)
SF3A1Uncharacterized protein. (790 aa)
SF3B1Splicing factor 3b subunit 1. (1301 aa)
PRPF4Pre-mRNA processing factor 4. (537 aa)
CWC22Pre-mRNA-splicing factor CWC22 homolog; Required for pre-mRNA splicing as component of the spliceosome. Promotes exon-junction complex (EJC) assembly. (926 aa)
LSM8U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
PRPF38APRP38_assoc domain-containing protein. (312 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
PHF5AUncharacterized protein. (110 aa)
SF3B4Splicing factor 3b subunit 4. (418 aa)
SF3B6Splicing factor 3b subunit 6. (91 aa)
WBP4WW domain-binding protein 4; Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex. (398 aa)
MFAP1Microfibrillar-associated protein 1; Involved in pre-mRNA splicing as a component of the spliceosome; Belongs to the MFAP1 family. (439 aa)
BUD13BUD13 homolog. (770 aa)
SNRPNSmall nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa)
SF3B5Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
LSM3Uncharacterized protein. (102 aa)
SNRPD1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
SNRNP200Helicase_PWI domain-containing protein. (614 aa)
ZMAT2U1-type domain-containing protein. (199 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
SNRPFSm domain-containing protein. (86 aa)
LSM6Sm domain-containing protein. (80 aa)
CWC27CWC27 spliceosome associated cyclophilin. (477 aa)
EFTUD2116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa)
TXNL4AThioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
ENSGALP00000066377Helicase C-terminal domain-containing protein. (528 aa)
SNRPGP15Small nuclear ribonucleoprotein G. (76 aa)
RBMX2RRM domain-containing protein. (253 aa)
LOC112530170SEC63 domain-containing protein. (235 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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