25 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PMCH	PMCH. (163 aa)
	HCRT	Uncharacterized protein. (148 aa)
	NPY	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
	GHRH	GHRH/PACAP-like. (172 aa)
	AGRP	Agouti-related protein. (233 aa)
	EDN2	Endothelin-2. (179 aa)
	APLN	Apelin. (78 aa)
	QRFP	Uncharacterized protein. (122 aa)
	UCN	Urocortin. (100 aa)
	MRAP2	Uncharacterized protein. (206 aa)
	NMU	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family. (181 aa)
	APELA	Apelin receptor early endogenous ligand. (54 aa)
	NTS	Neurotensin. (164 aa)
	GAL	Galanin variant 1. (141 aa)
	PPY	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. (80 aa)
	PIBPPDD4L	Phosphoinositide phospholipase C. (1139 aa)
	UCN3	Urocortin 3. (154 aa)
	ASIP	Agouti signaling protein. (139 aa)
	EDN3	Endothelin 3. (151 aa)
	PYY	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family. (90 aa)
	ADCYAP1	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family. (172 aa)
	POMC	Uncharacterized protein. (251 aa)
	TAC1	Tachykinin precursor 1. (114 aa)
	SPX	Spexin hormone. (116 aa)
	EDN1	Endothelin 1. (194 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1	GAL	ENSGALP00000062803	ENSGALP00000042337	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Galanin variant 1.	0.688
ADCYAP1	GHRH	ENSGALP00000062803	ENSGALP00000006088	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	GHRH/PACAP-like.	0.464
ADCYAP1	NMU	ENSGALP00000062803	ENSGALP00000031462	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Neuromedin-U-25; Stimulates uterine smooth muscle contraction and causes selective vasoconstriction; Belongs to the NmU family.	0.522
ADCYAP1	NPY	ENSGALP00000062803	ENSGALP00000017870	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.715
ADCYAP1	NTS	ENSGALP00000062803	ENSGALP00000040948	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Neurotensin.	0.577
ADCYAP1	POMC	ENSGALP00000062803	ENSGALP00000063133	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Uncharacterized protein.	0.560
ADCYAP1	PPY	ENSGALP00000062803	ENSGALP00000043946	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family.	0.454
ADCYAP1	TAC1	ENSGALP00000062803	ENSGALP00000063503	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Tachykinin precursor 1.	0.590
ADCYAP1	UCN	ENSGALP00000062803	ENSGALP00000071657	Pituitary adenylate cyclase-activating polypeptide 27; Primary role of GRF is to release GH from the pituitary; Belongs to the glucagon family.	Urocortin.	0.630
AGRP	APLN	ENSGALP00000003505	ENSGALP00000069961	Agouti-related protein.	Apelin.	0.402
AGRP	ASIP	ENSGALP00000003505	ENSGALP00000054181	Agouti-related protein.	Agouti signaling protein.	0.677
AGRP	GAL	ENSGALP00000003505	ENSGALP00000042337	Agouti-related protein.	Galanin variant 1.	0.588
AGRP	HCRT	ENSGALP00000003505	ENSGALP00000018699	Agouti-related protein.	Uncharacterized protein.	0.629
AGRP	MRAP2	ENSGALP00000003505	ENSGALP00000025492	Agouti-related protein.	Uncharacterized protein.	0.660
AGRP	NPY	ENSGALP00000003505	ENSGALP00000017870	Agouti-related protein.	C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family.	0.984
AGRP	NTS	ENSGALP00000003505	ENSGALP00000040948	Agouti-related protein.	Neurotensin.	0.620
AGRP	PMCH	ENSGALP00000003505	ENSGALP00000020790	Agouti-related protein.	PMCH.	0.695
AGRP	POMC	ENSGALP00000003505	ENSGALP00000063133	Agouti-related protein.	Uncharacterized protein.	0.985
AGRP	PPY	ENSGALP00000003505	ENSGALP00000043946	Agouti-related protein.	Pancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family.	0.556
AGRP	PYY	ENSGALP00000003505	ENSGALP00000059469	Agouti-related protein.	Peptide YY-like; This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Belongs to the NPY family.	0.822