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| | CIB2 | Uncharacterized protein. (203 aa) |
| | ENSGALP00000074194 | Uncharacterized protein. (401 aa) |
| | MICU2 | Mitochondrial calcium uptake 2. (506 aa) |
| | ATP13A5 | Uncharacterized protein. (253 aa) |
| | ENSGALP00000072903 | Uncharacterized protein. (81 aa) |
| | TMTC4 | Transmembrane O-mannosyltransferase targeting cadherins 4. (826 aa) |
| | KEL | Uncharacterized protein. (720 aa) |
| | HPS1 | Uncharacterized protein. (788 aa) |
| | ENSGALP00000072166 | IPT/TIG domain-containing protein. (239 aa) |
| | MICU1 | Mitochondrial calcium uptake 1. (502 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (488 aa) |
| | SLC39A12 | Solute carrier family 39 member 12. (702 aa) |
| | CNNM4 | Cyclin and CBS domain divalent metal cation transport mediator 4. (776 aa) |
| | ENSGALP00000071132 | Uncharacterized protein. (386 aa) |
| | ENSGALP00000070455 | Uncharacterized protein. (124 aa) |
| | SLC39A13 | Zinc transporter ZIP13; Acts as a zinc-influx transporter. (485 aa) |
| | ENSGALP00000069823 | Uncharacterized protein. (167 aa) |
| | PSEN1 | Presenilin-1 CTF subunit; Catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid- beta precursor protein). Requires the presence of the other members of the gamma-secretase complex for protease activity. Plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins. Belongs to the peptidase A22A family. (468 aa) |
| | SLC11A2 | Uncharacterized protein. (1307 aa) |
| | IMMT | MICOS complex subunit MIC60; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. (743 aa) |
| | PACS2 | Phosphofurin acidic cluster sorting protein 2. (917 aa) |
| | SLC39A6 | Solute carrier family 39 member 6. (720 aa) |
| | RGN | Regucalcin; Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium- binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). (299 aa) |
| | PKHD1 | Uncharacterized protein. (551 aa) |
| | ENSGALP00000067603 | Uncharacterized protein. (698 aa) |
| | ANKH | Uncharacterized protein. (493 aa) |
| | SLC10A7 | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates. Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (355 aa) |
| | ENSGALP00000066589 | Uncharacterized protein. (349 aa) |
| | TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (951 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1238 aa) |
| | LOC112530475 | B30.2/SPRY domain-containing protein. (311 aa) |
| | ATP2B2 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1274 aa) |
| | PMLL | Uncharacterized protein. (464 aa) |
| | TMEM165 | GDT1 family protein. (322 aa) |
| | LOC100858381 | Uncharacterized protein. (141 aa) |
| | SLC24A2 | Sodium/potassium/calcium exchanger 2; Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+); Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. SLC24A subfamily. (651 aa) |
| | ATP2A2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform SERCA2A is involved in the regulation of the contraction/relaxation cycle. May act as a regulator of TNFSF11-mediated Ca(2+) signaling during osteoclastogenesis. (1042 aa) |
| | TMCO1 | Calcium load-activated calcium channel; Calcium-selective channel required to prevent calcium stores from overfilling. (188 aa) |
| | SLC8A2 | Solute carrier family 8 member A2; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (916 aa) |
| | SLC35G1 | Solute carrier family 35 member G1. (376 aa) |
| | ANXA6 | Annexin A6; May associate with CD21. May regulate the release of Ca(2+) from intracellular stores (By similarity). (782 aa) |
| | ATP2B1 | Plasma membrane calcium-transporting ATPase 1; Catalyzes the hydrolysis of ATP coupled with the transport of calcium from the cytoplasm to the extracellular space thereby maintaining intracellular calcium homeostasis. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily. (1247 aa) |
| | SLC30A5 | Zinc transporter 5; Functions as a zinc transporter. Partly regulates cellular zinc homeostasis. Required with ZNT7 for activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (By similarity); Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily. (770 aa) |
| | EDN3 | Endothelin 3. (151 aa) |
| | CALB1 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. (262 aa) |
| | SYPL2 | Synaptophysin like 2. (425 aa) |
| | BAK1 | Uncharacterized protein. (216 aa) |
| | ANXA5 | Annexin A5; Collagen-binding protein. (321 aa) |
| | ATP2C1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (965 aa) |
| | ADCY8 | Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1240 aa) |
| | RMDN3 | Regulator of microtubule dynamics 3. (459 aa) |
| | TRPA1 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (1126 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1180 aa) |
| | TMEM64 | Transmembrane protein 64. (573 aa) |
| | GRIA1 | Uncharacterized protein. (902 aa) |
| | MICU3 | Mitochondrial calcium uptake family member 3. (511 aa) |
| | DHRS7C | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa) |
| | RYR3 | Uncharacterized protein. (4862 aa) |
| | RYR2 | Ryanodine receptor 2. (4957 aa) |
| | MCU | Mitochondrial calcium uniporter. (344 aa) |
| | ANXA2P2 | Annexin A2; Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. (339 aa) |
| | SLC39A14 | Solute carrier family 39 member 14. (508 aa) |
| | DISC1 | DISC1 scaffold protein. (856 aa) |
| | PKD2 | Uncharacterized protein. (881 aa) |
| | FAM20A | FAM20A golgi associated secretory pathway pseudokinase. (354 aa) |
| | TMTC2 | Transmembrane O-mannosyltransferase targeting cadherins 2. (836 aa) |
| | LOC100859230 | Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (892 aa) |
| | ATP13A1 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1254 aa) |
| | SLC30A8 | Solute carrier family 30 member 8. (384 aa) |
| | ASPH-2 | Asp-B-Hydro_N domain-containing protein. (350 aa) |
| | STIM1 | SAM domain-containing protein. (742 aa) |
| | PTH | Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family. (119 aa) |
| | SLC30A9 | Solute carrier family 30 member 9. (645 aa) |
| | MAIP1 | Matrix AAA peptidase interacting protein 1. (248 aa) |
| | CNNM2 | Cyclin and CBS domain divalent metal cation transport mediator 2. (858 aa) |
| | CAV1 | Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa) |
| | PLN | Cardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation (By similarity). (52 aa) |
| | MT4 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals; Belongs to the metallothionein superfamily. Type 1 family. (63 aa) |
| | FGF23 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (254 aa) |
| | CALB2 | Calretinin; Calretinin is a calcium-binding protein which is abundant in auditory neurons. (311 aa) |
| | SLC30A10 | Solute carrier family 30 member 10. (232 aa) |
| | TNFSF11 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (400 aa) |
| | STC2 | Stanniocalcin 2. (306 aa) |
| | TMEM203 | Transmembrane protein 203. (136 aa) |
| | ALPL | Alkaline phosphatase, tissue-nonspecific isozyme; This isozyme plays a key role in skeletal mineralization by regulating levels of diphosphate (PPi); Belongs to the alkaline phosphatase family. (519 aa) |
| | CD40 | Uncharacterized protein. (299 aa) |
| | SLC24A5 | Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (423 aa) |
| | ATF4 | ATF4. (354 aa) |
| | CASQ2 | Calsequestrin-2; Calsequestrin is a high-capacity, moderate affinity, calcium- binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats. (406 aa) |
| | APP | BPTI/Kunitz inhibitor domain-containing protein. (751 aa) |
| | SLC30A7 | Zinc transporter 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis (By similarity). Required with ZNT5 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP. (378 aa) |
| | HCRTR2 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (501 aa) |
| | TRPC2L | XRCC1_N domain-containing protein. (375 aa) |
| | TRPC4 | Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (974 aa) |
| | GRM5 | G_PROTEIN_RECEP_F3_4 domain-containing protein. (1242 aa) |
| | TRPC7 | Transient receptor potential cation channel subfamily C member 7; Belongs to the transient receptor (TC 1.A.4) family. (853 aa) |
| | HTR2A | 5-hydroxytryptamine (Serotonin) receptor 2A. (468 aa) |
| | RGNL | SGL domain-containing protein. (302 aa) |
| | NT5E | 5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (561 aa) |
| | LETM1 | Mitochondrial proton/calcium exchanger protein; Mitochondrial proton/calcium antiporter that mediates proton- dependent calcium efflux from mitochondrion (By similarity). Required for the maintenance of the tubular shape and cristae organization (By similarity). (755 aa) |
| | WFS1 | Wolframin ER transmembrane glycoprotein. (874 aa) |
| | CHRNA8 | Alpha8 subunit of nicotinic acetylcholine receptor. (511 aa) |
| | DRD3 | Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (425 aa) |
| | HEXB | Beta-hexosaminidase. (558 aa) |
| | TRPV6 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (724 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (63 aa) |
| | STIM2 | Stromal interaction molecule 2. (740 aa) |
| | KDR | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1348 aa) |
| | SCGN | Secretagogin, EF-hand calcium binding protein. (273 aa) |
| | BCL2 | Apoptosis regulator Bcl-2; Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). (233 aa) |
| | TRIM24 | Tripartite motif containing 24. (1165 aa) |
| | GCM2 | GCM domain-containing protein. (471 aa) |
| | EDN1 | Endothelin 1. (194 aa) |
| | MCUR1 | Mitochondrial calcium uniporter regulator 1. (273 aa) |
| | SLC39A8 | Solute carrier family 39 member 8. (493 aa) |
| | GRM1 | Glutamate metabotropic receptor 1. (1152 aa) |
| | MCUB | Mitochondrial calcium uniporter dominant negative beta subunit. (406 aa) |
| | SMDT1 | Single-pass membrane protein with aspartate rich tail 1. (94 aa) |
| | TRPC3 | ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family. (933 aa) |
| | SLC11A1 | Natural resistance-associated macrophage protein 1; Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis [...] (555 aa) |
| | SNX10 | PX domain-containing protein. (201 aa) |
| | SLC24A4 | Solute carrier family 24 member 4; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (528 aa) |
| | RMDN2 | Uncharacterized protein. (427 aa) |
| | EDNRA | Endothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa) |
| | SLC30A1 | Solute carrier family 30 member 1. (516 aa) |
| | SLC8A3 | Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (922 aa) |
| | SLC8A1 | Sodium calcium exchanger; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (969 aa) |
| | SLC24A3 | Solute carrier family 24 member 3; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (595 aa) |
| | CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa) |
| | F2 | Uncharacterized protein; Belongs to the peptidase S1 family. (644 aa) |
| | TRPC5 | Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (969 aa) |
| | SLC39A10 | Solute carrier family 39 member 10. (719 aa) |
| | SLC37A4 | Solute carrier family 37 member 4. (451 aa) |
| | HTR2B | Serotonin receptor subtype 2b. (462 aa) |
| | TPCN2 | Uncharacterized protein. (753 aa) |
| | VAPB | MSP domain-containing protein. (243 aa) |
| | SLC24A1 | Sodium/potassium/calcium exchanger 1; Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). (663 aa) |
| | CNNM1 | Cyclin and CBS domain divalent metal cation transport mediator 1. (888 aa) |
| | ATP13A4 | Probable cation-transporting ATPase 13A4; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1205 aa) |
| | SLC30A4 | Uncharacterized protein. (429 aa) |
| | PIK3CB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa) |
| | SELENOK | Uncharacterized protein. (92 aa) |
| | C11H19orf12 | Uncharacterized protein. (306 aa) |
| | CHRNA7 | Neuronal acetylcholine receptor subunit alpha-7; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane; Belongs to the ligand-gated ion channel (TC 1.A.9) family. Acetylcholine receptor (TC 1.A.9.1) subfamily. Alpha-7/CHRNA7 sub- subfamily. (502 aa) |
| | GPER1 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa) |
| | CSRP3 | Uncharacterized protein. (194 aa) |
| | CHERP | Uncharacterized protein. (1018 aa) |
| | TRPC1 | Transient receptor potential cation channel subfamily C member 1 isoform alpha; Belongs to the transient receptor (TC 1.A.4) family. (781 aa) |
| | STOML2 | Stomatin like 2. (382 aa) |
| | NPTN | Uncharacterized protein. (397 aa) |
| | ATP2A3 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 3; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily. (1042 aa) |
| | HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (401 aa) |
| | SELENON | Uncharacterized protein. (66 aa) |
| | EDN2 | Endothelin-2. (179 aa) |
| | CCDC47 | Coiled-coil domain containing 47. (481 aa) |
| | LCK | Proto-oncogene tyrosine-protein kinase LCK; Tyrosine kinase that plays an essential role for the selection and maturation of developing T-cell in the thymus and in mature T-cell function. Is constitutively associated with the cytoplasmic portions of the CD4 and CD8 surface receptors and plays a key role in T-cell antigen receptor(TCR)-linked signal transduction pathways (By similarity); Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. (508 aa) |
| | STC1 | Stanniocalcin 1. (247 aa) |
