46 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LUC7L3	Uncharacterized protein. (469 aa)
	LOC112530170	SEC63 domain-containing protein. (235 aa)
	RBMX2	RRM domain-containing protein. (253 aa)
	SNRPGP15	Small nuclear ribonucleoprotein G. (76 aa)
	TXNL4A	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	EFTUD2	116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity). (1222 aa)
	LSM6	Sm domain-containing protein. (80 aa)
	SNRPF	Sm domain-containing protein. (86 aa)
	LSM5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	ZMAT2	U1-type domain-containing protein. (199 aa)
	SNRNP200	Helicase_PWI domain-containing protein. (614 aa)
	DDX23	DEAD-box helicase 23. (816 aa)
	PRPF18	SFM domain-containing protein. (351 aa)
	SNRPD1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	LSM3	Uncharacterized protein. (102 aa)
	SART3	Spliceosome associated factor 3, U4/U6 recycling protein. (943 aa)
	SF3B5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	SNRPN	Small nuclear ribonucleoprotein-associated protein B; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (By similarity). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (By similarity). Is also a component of the minor U12 spliceosome (By similarity). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing (By similarity). (240 aa)
	LUC7L2	Uncharacterized protein. (398 aa)
	SNRPB2	Small nuclear ribonucleoprotein polypeptide B2. (226 aa)
	NWD1	WD_REPEATS_REGION domain-containing protein. (425 aa)
	PRPF3	U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). (684 aa)
	SF3B6	Splicing factor 3b subunit 6. (91 aa)
	TXNL4B	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (149 aa)
	PRPF40A	Pre-mRNA processing factor 40 homolog A. (853 aa)
	PHF5A	Uncharacterized protein. (110 aa)
	SNU13	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	PRPF4	Pre-mRNA processing factor 4. (537 aa)
	SF3B1	Splicing factor 3b subunit 1. (1301 aa)
	SF3A1	Uncharacterized protein. (790 aa)
	SNRPA1	LRRcap domain-containing protein. (255 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3. (126 aa)
	HTATSF1	HIV-1 Tat specific factor 1. (450 aa)
	PRPF6	Pre-mRNA processing factor 6. (941 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (138 aa)
	PRPF8	Pre-mRNA processing factor 8. (2335 aa)
	SNRPC	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (160 aa)
	SF3B3	Splicing factor 3b subunit 3. (1217 aa)
	SF3A3	Splicing factor 3a subunit 3. (501 aa)
	SF3A2	Splicing factor 3a subunit 2. (315 aa)
	SNRPE	Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (92 aa)
	LUC7L	LUC7 like. (332 aa)
	SNRPD2	Small nuclear ribonucleoprotein Sm D2. (146 aa)
	PRPF39	Pre-mRNA processing factor 39. (680 aa)
	ENSGALP00000070086	Uncharacterized protein. (597 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX23	EFTUD2	ENSGALP00000056569	ENSGALP00000064066	DEAD-box helicase 23.	116 kDa U5 small nuclear ribonucleoprotein component; Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes (By similarity). Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome (By similarity).	0.994
DDX23	ENSGALP00000070086	ENSGALP00000056569	ENSGALP00000070086	DEAD-box helicase 23.	Uncharacterized protein.	0.707
DDX23	HTATSF1	ENSGALP00000056569	ENSGALP00000010334	DEAD-box helicase 23.	HIV-1 Tat specific factor 1.	0.602
DDX23	LOC112530170	ENSGALP00000056569	ENSGALP00000069373	DEAD-box helicase 23.	SEC63 domain-containing protein.	0.850
DDX23	LSM3	ENSGALP00000056569	ENSGALP00000050320	DEAD-box helicase 23.	Uncharacterized protein.	0.576
DDX23	LSM4	ENSGALP00000056569	ENSGALP00000005338	DEAD-box helicase 23.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.646
DDX23	LSM5	ENSGALP00000056569	ENSGALP00000058042	DEAD-box helicase 23.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.623
DDX23	LSM6	ENSGALP00000056569	ENSGALP00000063047	DEAD-box helicase 23.	Sm domain-containing protein.	0.697
DDX23	LSM8	ENSGALP00000056569	ENSGALP00000014820	DEAD-box helicase 23.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.558
DDX23	LUC7L	ENSGALP00000056569	ENSGALP00000073914	DEAD-box helicase 23.	LUC7 like.	0.730
DDX23	LUC7L2	ENSGALP00000056569	ENSGALP00000043994	DEAD-box helicase 23.	Uncharacterized protein.	0.730
DDX23	LUC7L3	ENSGALP00000056569	ENSGALP00000048736	DEAD-box helicase 23.	Uncharacterized protein.	0.647
DDX23	NWD1	ENSGALP00000056569	ENSGALP00000040424	DEAD-box helicase 23.	WD_REPEATS_REGION domain-containing protein.	0.987
DDX23	PHF5A	ENSGALP00000056569	ENSGALP00000019471	DEAD-box helicase 23.	Uncharacterized protein.	0.721
DDX23	PRPF18	ENSGALP00000056569	ENSGALP00000055559	DEAD-box helicase 23.	SFM domain-containing protein.	0.655
DDX23	PRPF3	ENSGALP00000056569	ENSGALP00000039818	DEAD-box helicase 23.	U4/U6 small nuclear ribonucleoprotein Prp3; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex).	0.946
DDX23	PRPF39	ENSGALP00000056569	ENSGALP00000070190	DEAD-box helicase 23.	Pre-mRNA processing factor 39.	0.817
DDX23	PRPF4	ENSGALP00000056569	ENSGALP00000014372	DEAD-box helicase 23.	Pre-mRNA processing factor 4.	0.930
DDX23	PRPF6	ENSGALP00000056569	ENSGALP00000009642	DEAD-box helicase 23.	Pre-mRNA processing factor 6.	0.994
DDX23	PRPF8	ENSGALP00000056569	ENSGALP00000004641	DEAD-box helicase 23.	Pre-mRNA processing factor 8.	0.999