STRINGSTRING
DRD5 DRD5 ADRA1A ADRA1A UTS2 UTS2 EDN2 EDN2 HTR1D HTR1D ADRA1B ADRA1B UTS2R-2 UTS2R-2 OXTR OXTR SCPEP1 SCPEP1 P2RX4 P2RX4 GPER1 GPER1 P2RY4 P2RY4 SCNN1B SCNN1B UTS2B UTS2B HTR2B HTR2B CAV3 CAV3 ADRB1 ADRB1 MKKS MKKS FGG FGG AVPR2 AVPR2 EDNRA EDNRA BDKRB2 BDKRB2 AGT AGT PLA2G6 PLA2G6 EDN1 EDN1 HTR1A HTR1A ADRA2C ADRA2C HTR1B HTR1B GCLC GCLC ITGB1BP1 ITGB1BP1 ADORA2B ADORA2B ADRB3 ADRB3 AVPR1B AVPR1B EDNRB EDNRB ADRA2A ADRA2A UTS2R UTS2R HRH2 HRH2 ZDHHC21 ZDHHC21 CAV1 CAV1 SNTA1 SNTA1 AVPR1A AVPR1A HTR7L HTR7L DBH DBH EXT2 EXT2 ADRB2 ADRB2 HTR7 HTR7 GRIP2 GRIP2 ATG5 ATG5 ROCK1 ROCK1 DRD1 DRD1 SMTNL2 SMTNL2 TBXA2R TBXA2R ADRA1D ADRA1D EDN3 EDN3 ADRA2BL2 ADRA2BL2 BBS2 BBS2 AGTR1 AGTR1 NPR3 NPR3 BMPR2 BMPR2 DOCK4 DOCK4 AGTR2 AGTR2 ADRA2B ADRA2B ACTA2 ACTA2 SERPINF2 SERPINF2 UTS2R2 UTS2R2 ENSGALP00000070591 ENSGALP00000070591 UCN UCN EDNRB2 EDNRB2 ACTG2 ACTG2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (425 aa)
ADRA1AAdrenoceptor alpha 1A. (467 aa)
UTS2Preprourotensin II. (124 aa)
EDN2Endothelin-2. (179 aa)
HTR1DG_PROTEIN_RECEP_F1_2 domain-containing protein. (378 aa)
ADRA1BAdrenoceptor alpha 1B. (507 aa)
UTS2R-2Urotensin 2 receptor; Belongs to the G-protein coupled receptor 1 family. (382 aa)
OXTROxytocin-like receptor. (391 aa)
SCPEP1Carboxypeptidase; Belongs to the peptidase S10 family. (446 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (385 aa)
GPER1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (357 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (448 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (667 aa)
UTS2BUncharacterized protein. (126 aa)
HTR2BSerotonin receptor subtype 2b. (462 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
ADRB1Adrenoceptor beta 1. (477 aa)
MKKSUncharacterized protein. (570 aa)
FGGFibrinogen C-terminal domain-containing protein. (438 aa)
AVPR2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (370 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (421 aa)
BDKRB2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (391 aa)
AGTAngiotensinogen; Belongs to the serpin family. (464 aa)
PLA2G6Uncharacterized protein. (796 aa)
EDN1Endothelin 1. (194 aa)
HTR1A5-hydroxytryptamine receptor 1A. (413 aa)
ADRA2CAdrenoceptor alpha 2C. (446 aa)
HTR1B5-hydroxytryptamine receptor 1B. (379 aa)
GCLCGlutamate-cysteine ligase catalytic subunit. (636 aa)
ITGB1BP1PID domain-containing protein. (208 aa)
ADORA2BAdenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (340 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (425 aa)
AVPR1BG_PROTEIN_RECEP_F1_2 domain-containing protein. (425 aa)
EDNRBG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (560 aa)
ADRA2AAdrenoceptor alpha 2A. (444 aa)
UTS2RUrotensin 2 receptor 5; Belongs to the G-protein coupled receptor 1 family. (363 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (377 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
CAV1Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa)
SNTA1Syntrophin alpha 1. (484 aa)
AVPR1AG_PROTEIN_RECEP_F1_2 domain-containing protein. (418 aa)
HTR7L5-hydroxytryptamine receptor 7-like protein; Belongs to the G-protein coupled receptor 1 family. (426 aa)
DBHDopamine beta-hydroxylase. (584 aa)
EXT2Uncharacterized protein; Belongs to the glycosyltransferase 47 family. (717 aa)
ADRB2Adrenoceptor beta 2. (402 aa)
HTR75-hydroxytryptamine receptor 7 transcript variant 1. (461 aa)
GRIP2Glutamate receptor interacting protein 2. (1104 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (288 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1384 aa)
DRD1Dopamine receptor D1; Belongs to the G-protein coupled receptor 1 family. (487 aa)
SMTNL2Smoothelin like 2. (468 aa)
TBXA2RThromboxane A2 receptor. (361 aa)
ADRA1DAdrenoceptor alpha 1D. (511 aa)
EDN3Endothelin 3. (151 aa)
ADRA2BL2Adrenoceptor alpha 2B-like 2. (345 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (721 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. (359 aa)
NPR3Natriuretic peptide receptor 3. (521 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1031 aa)
DOCK4Dedicator of cytokinesis 4; Belongs to the DOCK family. (2023 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (372 aa)
ADRA2BAdrenoceptor alpha 2B; Belongs to the G-protein coupled receptor 1 family. (534 aa)
ACTA2Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (377 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (514 aa)
UTS2R2Urotensin 2 receptor 2; Belongs to the G-protein coupled receptor 1 family. (343 aa)
ENSGALP00000070591G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (431 aa)
UCNUrocortin. (100 aa)
EDNRB2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (479 aa)
ACTG2Actin, gamma-enteric smooth muscle. (506 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.