STRINGSTRING
GH GH STX12 STX12 HYAL1 HYAL1 TPRG1L TPRG1L BSG BSG TEKT3 TEKT3 RAB40B RAB40B SLC18A1 SLC18A1 ROGDI ROGDI SYT6 SYT6 UNC13B UNC13B UNC13D UNC13D MOXD1 MOXD1 C11H16orf70 C11H16orf70 ATP6V0A2 ATP6V0A2 RAB8B RAB8B PLAT PLAT POMT1 POMT1 STX10 STX10 PPT1 PPT1 TMEM184A TMEM184A SYT12 SYT12 OPNP OPNP SERPINE2 SERPINE2 GHRHR GHRHR SYT9 SYT9 HPS4 HPS4 BTBD8 BTBD8 ABCC8 ABCC8 SYT8 SYT8 GRIN2A GRIN2A SYP SYP RAB35 RAB35 TMPRSS4 TMPRSS4 ENKUR ENKUR TRAPPC4 TRAPPC4 SPAG6 SPAG6 SYT13 SYT13 HSPD1 HSPD1 CAV3 CAV3 LOC772071 LOC772071 TRH TRH E1BU02_CHICK E1BU02_CHICK ATP6AP1 ATP6AP1 SNAP25 SNAP25 SNAP23 SNAP23 NCSTN NCSTN ATP6V0C ATP6V0C FGG FGG SLC18A2 SLC18A2 CAPN8 CAPN8 CALCR CALCR VTI1B VTI1B THBS1 THBS1 SCG5 SCG5 GTPBP2 GTPBP2 TMED10 TMED10 MMRN1 MMRN1 RAB3B RAB3B STON2 STON2 TRIP11 TRIP11 MEPE MEPE NPY NPY SNX10 SNX10 COPS4 COPS4 PLAC8 PLAC8 BIN1 BIN1 STX11 STX11 SYNGR1 SYNGR1 TMEM163 TMEM163 TRIM9 TRIM9 CTSV CTSV THL THL ATP6V1E1 ATP6V1E1 SPX SPX ZPBP2 ZPBP2 ITPR2 ITPR2 AVP AVP GABRA2 GABRA2 PCSK1 PCSK1 RAB3C RAB3C HEXB HEXB S100Z S100Z CRHBP CRHBP PLA1A PLA1A DENND4C DENND4C PAM PAM PENK PENK WFS1 WFS1 SYTL5 SYTL5 OLFM4 OLFM4 RCBTB2 RCBTB2 BRCA2 BRCA2 TSTD1 TSTD1 PLA2G10L PLA2G10L DEFB4A DEFB4A SV2C SV2C PLA2G10 PLA2G10 VAMP3 VAMP3 BSN BSN ATP6AP2 ATP6AP2 AvBD1 AvBD1 RAB10 RAB10 APP APP ZPBP ZPBP OXT OXT CYB561 CYB561 NUDT1 NUDT1 SNAPIN SNAPIN SLC17A9 SLC17A9 CPLX3 CPLX3 RAB8A RAB8A BMF BMF SYT1 SYT1 GAL GAL STBD1 STBD1 SYPL1 SYPL1 SYNGR2 SYNGR2 CAV1 CAV1 COPS5 COPS5 RAB37 RAB37 SYNDIG1 SYNDIG1 SCG2 SCG2 AP2A2 AP2A2 RAB3IP RAB3IP UNC13A UNC13A SPAG17 SPAG17 STX1A STX1A SVOP SVOP STX2 STX2 SCG3 SCG3 RAB12 RAB12 SLC30A8 SLC30A8 UNC13C UNC13C SCFD2 SCFD2 SLC40A1 SLC40A1 RAB26 RAB26 LOC425940 LOC425940 BAIAP2 BAIAP2 MYRIP MYRIP RAB40C RAB40C TCIRG1 TCIRG1 AMPH AMPH ASTL ASTL SCNN1A SCNN1A ICA1 ICA1 DLD DLD SEPT5 SEPT5 PTPRN2 PTPRN2 SYT2 SYT2 DBH DBH SYTL2 SYTL2 ACPP ACPP F5 F5 ATP6V0A1 ATP6V0A1 DISC1 DISC1 RAB3A RAB3A SNAP91 SNAP91 BORCS5 BORCS5 STXBP5L STXBP5L SEC11A SEC11A ATP6V1C1 ATP6V1C1 PTPRN PTPRN MYO5A MYO5A SLC4A8 SLC4A8 SPATA16 SPATA16 SYT4 SYT4 ECRG4 ECRG4 TH TH CAPN1 CAPN1 ENSGALP00000051312 ENSGALP00000051312 PICALM PICALM PTPRD PTPRD CTSH CTSH CAPN11 CAPN11 SEPT4 SEPT4 STXBP1 STXBP1 LRRK2 LRRK2 VAMP4 VAMP4 GRIA1 GRIA1 LAMP1 LAMP1 VPS13A VPS13A CLTB CLTB VAMP2 VAMP2 MYO5C MYO5C MYH9 MYH9 LOC100859819 LOC100859819 VPS45 VPS45 BCL2L1 BCL2L1 SYN3 SYN3 CFAP65 CFAP65 SLC32A1 SLC32A1 GAD2 GAD2 STX16 STX16 LOC100857259 LOC100857259 SEC11C SEC11C TBXA2R TBXA2R SYPL2 SYPL2 CARTPT CARTPT SLC17A6 SLC17A6 SYT17 SYT17 LRGUK LRGUK PTPRS PTPRS SLC17A8 SLC17A8 GMFB GMFB SYT7 SYT7 SPACA9 SPACA9 STX7 STX7 LOC776719 LOC776719 LOC422353 LOC422353 SV2B SV2B C1orf35 C1orf35 ENSGALP00000058230 ENSGALP00000058230 MCTP2 MCTP2 KNL1 KNL1 UVS.2L UVS.2L VTI1A VTI1A TMEM230 TMEM230 SYT15 SYT15 SEPT2L SEPT2L LAMP5 LAMP5 SYT11 SYT11 SPACA1 SPACA1 HEXA HEXA SCAMP1 SCAMP1 DNASE1 DNASE1 IFT20 IFT20 POMC POMC RAB10L RAB10L GARS GARS CAV2 CAV2 VPS33B VPS33B MFF MFF CHGB CHGB DNASE1L2 DNASE1L2 EBAG9 EBAG9 SLC30A3 SLC30A3 STXBP3 STXBP3 CCDC189 CCDC189 SFTPC SFTPC UNC13C-2 UNC13C-2 SCNN1D SCNN1D STK31 STK31 STX3 STX3 ABHD2 ABHD2 ENSGALP00000066467 ENSGALP00000066467 RAB27A RAB27A SEPTIN2 SEPTIN2 LGI3 LGI3 RAB15 RAB15 APBA1 APBA1 SYTL3 SYTL3 STX19 STX19 HYAL6 HYAL6 HYAL3 HYAL3 STXBP5 STXBP5 ANXA11 ANXA11 TSSK3 TSSK3 SYTL1 SYTL1 DTNBP1 DTNBP1 ENSGALP00000068902 ENSGALP00000068902 SYN2 SYN2 CAPN14 CAPN14 VPS13C VPS13C TRARG1 TRARG1 SYCN SYCN SNAP47 SNAP47 CLTA CLTA SYNGR3 SYNGR3 KIAA1210 KIAA1210 ENSGALP00000070006 ENSGALP00000070006 GRP GRP STON1 STON1 TMED2 TMED2 NTF3 NTF3 RAB3IL1 RAB3IL1 ATP6V1A ATP6V1A ENSGALP00000070662 ENSGALP00000070662 PHACTR2 PHACTR2 DNM1L DNM1L RAB2A RAB2A ENSGALP00000071604 ENSGALP00000071604 IQUB IQUB BDNF BDNF ITPR1 ITPR1 APBA2 APBA2 SYT10 SYT10 VPS13B VPS13B RAB4A RAB4A SPATA1 SPATA1 CBARP CBARP SV2A SV2A SYTL4 SYTL4 NGF NGF MCTP1 MCTP1 CEP131 CEP131 VAMP1 VAMP1 LOC112530958 LOC112530958 ENSGALP00000074167 ENSGALP00000074167
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GHSomatotropin; Growth hormone plays an important role in growth control. (216 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (272 aa)
HYAL1Hyaluronidase. (436 aa)
TPRG1LTumor protein p63 regulated 1 like. (270 aa)
BSGBasigin; Plays an important role in targeting monocarboxylate transporters to the plasma membrane (By similarity). Probable receptor involved in cell surface recognition at the blood-brain barrier. Involved in neuronal-glial interactions in retinal development. (388 aa)
TEKT3Tektin 3. (490 aa)
RAB40BSOCS box domain-containing protein. (278 aa)
SLC18A1Solute carrier family 18 member A1. (515 aa)
ROGDIRogdi atypical leucine zipper. (286 aa)
SYT6Synaptotagmin 6. (414 aa)
UNC13BUnc-13 homolog B. (1574 aa)
UNC13DUnc-13 homolog D. (708 aa)
MOXD1DBH-like monooxygenase protein 1. (614 aa)
C11H16orf70Uncharacterized protein. (423 aa)
ATP6V0A2V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (839 aa)
RAB8BRAB8B, member RAS oncogene family. (201 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (567 aa)
POMT1Uncharacterized protein. (724 aa)
STX10Syntaxin-6; Involved in intracellular vesicle trafficking; Belongs to the syntaxin family. (254 aa)
PPT1Uncharacterized protein. (300 aa)
TMEM184ATransmembrane protein 184A. (425 aa)
SYT12C2 domain-containing protein. (417 aa)
OPNPPinopsin; Produces a slow and prolonged phototransduction response consistent with the non-visual function of pineal photoreception. (351 aa)
SERPINE2SERPIN domain-containing protein; Belongs to the serpin family. (442 aa)
GHRHRG protein-coupled pituitary GHRH receptor; Belongs to the G-protein coupled receptor 2 family. (419 aa)
SYT9Synaptotagmin 9. (528 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (702 aa)
BTBD8BTB domain containing 8. (1780 aa)
ABCC8ATP binding cassette subfamily C member 8. (1595 aa)
SYT8Synaptotagmin 8. (396 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1458 aa)
SYPMARVEL domain-containing protein. (338 aa)
RAB35Uncharacterized protein. (201 aa)
TMPRSS4Uncharacterized protein; Belongs to the peptidase S1 family. (405 aa)
ENKUREnkurin, TRPC channel interacting protein. (253 aa)
TRAPPC4Uncharacterized protein. (293 aa)
SPAG6Uncharacterized protein. (508 aa)
SYT13C2 domain-containing protein. (430 aa)
HSPD160 kDa heat shock protein, mitochondrial; Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. The functional units of these chaperonins consist of heptameric rings of the large subunit Hsp60, which function as a back-to-back double ring. In a cyclic reaction, Hsp60 ring complexes bind one unfolded substrate protein per rin [...] (573 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
LOC772071ENTH domain-containing protein. (624 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems; Belongs to the TRH family. (260 aa)
E1BU02_CHICKSpermatogenesis associated 1. (335 aa)
ATP6AP1Uncharacterized protein. (455 aa)
SNAP25Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion (By similarity). Belongs to the SNAP-25 family. (206 aa)
SNAP23Synaptosomal-associated protein; Belongs to the SNAP-25 family. (209 aa)
NCSTNNcstrn_small domain-containing protein. (717 aa)
ATP6V0CV-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
FGGFibrinogen C-terminal domain-containing protein. (438 aa)
SLC18A2Solute carrier family 18 member A2. (633 aa)
CAPN8Calpain 8; Belongs to the peptidase C2 family. (702 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (469 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
THBS1Uncharacterized protein. (1175 aa)
SCG5Uncharacterized protein. (208 aa)
GTPBP2GTP binding protein 2. (605 aa)
TMED10GOLD domain-containing protein. (219 aa)
MMRN1Multimerin 1. (1192 aa)
RAB3BRAB3B, member RAS oncogene family. (226 aa)
STON2Stonin-2; Adapter protein involved in endocytic machinery. Involved in the synaptic vesicle recycling. May facilitate clathrin-coated vesicle uncoating; Belongs to the Stoned B family. (887 aa)
TRIP11Thyroid hormone receptor interactor 11. (1980 aa)
MEPEOvocleidin-116; Major component of the eggshell matrix. May play an important role in the regulation of calcite growth during eggshell calcification. May also regulate the mineralization process in developing and growing bones. (743 aa)
NPYC-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. (97 aa)
SNX10PX domain-containing protein. (201 aa)
COPS4PCI domain-containing protein. (411 aa)
PLAC8Uncharacterized protein. (145 aa)
BIN1Uncharacterized protein. (442 aa)
STX11Syntaxin 11. (288 aa)
SYNGR1Synaptogyrin. (233 aa)
TMEM163Transmembrane protein 163. (274 aa)
TRIM9Tripartite motif containing 9. (802 aa)
CTSVCathepsin L1 heavy chain; Important for the overall degradation of proteins in lysosomes; Belongs to the peptidase C1 family. (353 aa)
THLBH4_AAA_HYDROXYL_2 domain-containing protein. (443 aa)
ATP6V1E1Uncharacterized protein. (226 aa)
SPXSpexin hormone. (116 aa)
ZPBP2Zona pellucida-binding protein 2; May be implicated in the gamete interaction during fertilization; Belongs to the zona pellucida-binding protein Sp38 family. (352 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2700 aa)
AVPVasotocin-neurophysin VT; Vasotocin is an antidiuretic hormone. (161 aa)
GABRA2Gamma-aminobutyric acid type A receptor alpha2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (455 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (748 aa)
RAB3CRAB3C, member RAS oncogene family. (227 aa)
HEXBBeta-hexosaminidase. (558 aa)
S100ZProtein S100; Belongs to the S-100 family. (98 aa)
CRHBPCorticotropin-releasing factor-binding protein; Binds CRF and inactivates it. May prevent inappropriate pituitary-adrenal stimulation in pregnancy. Belongs to the CRF-binding protein family. (345 aa)
PLA1APhospholipase A1 member A. (456 aa)
DENND4CDENN domain containing 4C. (1950 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (970 aa)
PENKProenkephalin. (267 aa)
WFS1Wolframin ER transmembrane glycoprotein. (874 aa)
SYTL5Synaptotagmin like 5. (764 aa)
OLFM4Olfactomedin-like domain-containing protein. (489 aa)
RCBTB2RCC1 and BTB domain containing protein 2. (570 aa)
BRCA2Tower domain-containing protein. (3397 aa)
TSTD1Uncharacterized protein. (358 aa)
PLA2G10LPhospholipase A(2). (158 aa)
DEFB4AGallinacin-2; Potent antibacterial activity against the Gram-negative bacterium E.coli ML-35, and against the Gram-positive bacterium L.monocytogenes EGD. Lacks antifungal activity against C.albicans. (64 aa)
SV2CSynaptic vesicle glycoprotein 2C. (727 aa)
PLA2G10Phospholipase A(2). (155 aa)
VAMP3V-SNARE coiled-coil homology domain-containing protein. (104 aa)
BSNBassoon presynaptic cytomatrix protein. (3627 aa)
ATP6AP2Uncharacterized protein. (354 aa)
AvBD1Gallinacin-1; Has bactericidal activity. Potent activity against E.coli ML- 35, L.monocytogenes EGD and C.albicans. (65 aa)
RAB10Ras-related protein Rab-10; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is mainly involved in the biosynthetic transport of proteins from the Golgi to the plasma membrane. Plays also a specific role in asymmetric protein transport to the plasma mem [...] (200 aa)
APPBPTI/Kunitz inhibitor domain-containing protein. (751 aa)
ZPBPZona pellucida-binding protein 1; Plays a role in sperm morphogenesis and in sperm-oocyte interaction during fertilization; Belongs to the zona pellucida-binding protein Sp38 family. (344 aa)
OXTMesotocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (124 aa)
CYB561Cytochrome b561. (252 aa)
NUDT1Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family. (156 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (126 aa)
SLC17A9MFS domain-containing protein. (606 aa)
CPLX3Uncharacterized protein. (157 aa)
RAB8ARas-related protein Rab-8A; May be involved in vesicular trafficking and neurotransmitter release; Belongs to the small GTPase superfamily. Rab family. (207 aa)
BMFUncharacterized protein. (200 aa)
SYT1Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. May play a role in dendrite formation by melanocytes; Belongs to the synaptotagmin family. (430 aa)
GALGalanin variant 1. (141 aa)
STBD1Starch binding domain 1. (290 aa)
SYPL1MARVEL domain-containing protein. (236 aa)
SYNGR2Synaptogyrin. (225 aa)
CAV1Caveolin-1; May act as a positive regulator of T-cell coactivation. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). (178 aa)
COPS5MPN domain-containing protein. (337 aa)
RAB37RAB37, member RAS oncogene family. (371 aa)
SYNDIG1Synapse differentiation inducing 1. (256 aa)
SCG2Secretogranin II. (629 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
RAB3IPUncharacterized protein. (467 aa)
UNC13AUncharacterized protein. (1738 aa)
SPAG17Sperm associated antigen 17. (1778 aa)
STX1ASyntaxin 1A; Belongs to the syntaxin family. (407 aa)
SVOPSV2 related protein. (548 aa)
STX2t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (288 aa)
SCG3Uncharacterized protein. (469 aa)
RAB12RAB12, member RAS oncogene family. (290 aa)
SLC30A8Solute carrier family 30 member 8. (384 aa)
UNC13CUncharacterized protein. (1097 aa)
SCFD2Sec1 family domain containing 2; Belongs to the STXBP/unc-18/SEC1 family. (652 aa)
SLC40A1Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (581 aa)
RAB26RAB26, member RAS oncogene family. (190 aa)
LOC425940Uncharacterized protein. (1491 aa)
BAIAP2BAI1 associated protein 2. (573 aa)
MYRIPRab_eff_C domain-containing protein. (666 aa)
RAB40CSOCS box domain-containing protein. (281 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (825 aa)
AMPHAmphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. (682 aa)
ASTLAstacin-like metalloendopeptidase; Probable oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. May act as a protease (By similarity). (409 aa)
SCNN1AAmiloride-sensitive sodium channel subunit alpha; Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. (612 aa)
ICA1Islet cell autoantigen 1. (676 aa)
DLDDihydrolipoyl dehydrogenase. (508 aa)
SEPT5Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (485 aa)
PTPRN2Protein tyrosine phosphatase receptor type N2. (1030 aa)
SYT2Synaptotagmin 2. (490 aa)
DBHDopamine beta-hydroxylase. (584 aa)
SYTL2Synaptotagmin like 2. (863 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (390 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2025 aa)
ATP6V0A1V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). (863 aa)
DISC1DISC1 scaffold protein. (856 aa)
RAB3ARAB3A, member RAS oncogene family. (220 aa)
SNAP91ENTH domain-containing protein. (907 aa)
BORCS5BLOC-1-related complex subunit 5; As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. Belongs to the BORCS5 family. (196 aa)
STXBP5LSyntaxin binding protein 5 like. (1184 aa)
SEC11ASignal peptidase complex catalytic subunit SEC11. (179 aa)
ATP6V1C1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (382 aa)
PTPRNProtein tyrosine phosphatase receptor type N. (946 aa)
MYO5AUnconventional myosin-Va; Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (By similarity). (1830 aa)
SLC4A8Anion exchange protein. (1068 aa)
SPATA16Spermatogenesis associated 16. (531 aa)
SYT4Synaptotagmin 4. (425 aa)
ECRG4ECRG4 augurin precursor. (112 aa)
THTyrosine hydroxylase. (491 aa)
CAPN1Uncharacterized protein; Belongs to the peptidase C2 family. (715 aa)
ENSGALP00000051312Uncharacterized protein. (411 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (609 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1963 aa)
CTSHUncharacterized protein; Belongs to the peptidase C1 family. (403 aa)
CAPN11Calpain-1 catalytic subunit; Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction; Belongs to the peptidase C2 family. (705 aa)
SEPT4Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (476 aa)
STXBP1Syntaxin-binding protein 1; May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxins, components of the synaptic vesicle fusion machinery. May play a role in determining the specificity of intracellular fusion reactions (By similarity). Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
LRRK2Uncharacterized protein. (2557 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
GRIA1Uncharacterized protein. (902 aa)
LAMP1Lysosome-associated membrane glycoprotein 1; Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis; Belongs to the LAMP family. (406 aa)
VPS13AUncharacterized protein. (3193 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (228 aa)
VAMP2V-SNARE coiled-coil homology domain-containing protein. (114 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1737 aa)
MYH9Myosin-9; Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. (1960 aa)
LOC100859819CARTL. (113 aa)
VPS45Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (397 aa)
BCL2L1Bcl-2-like protein 1; Dominant regulator of apoptotic cell death. The long form displays cell death repressor activity, whereas the short isoform promotes apoptosis. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis (By similarity). (229 aa)
SYN3Synapsin III. (582 aa)
CFAP65Cilia- and flagella-associated protein 65; May play a role in sperm motility. (1775 aa)
SLC32A1Solute carrier family 32 member 1. (521 aa)
GAD2Glutamate decarboxylase 2. (807 aa)
STX16t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (326 aa)
LOC100857259Aa_trans domain-containing protein. (486 aa)
SEC11CSignal peptidase complex catalytic subunit SEC11. (177 aa)
TBXA2RThromboxane A2 receptor. (361 aa)
SYPL2Synaptophysin like 2. (425 aa)
CARTPTCART prepropeptide. (111 aa)
SLC17A6MFS domain-containing protein. (585 aa)
SYT17Synaptotagmin 17. (474 aa)
LRGUKLeucine rich repeats and guanylate kinase domain containing. (740 aa)
PTPRSReceptor-type tyrosine-protein phosphatase S; Cell surface receptor that binds to glycosaminoglycans, including chondroitin sulfate proteoglycans and heparan sulfate proteoglycans. Binding to chondroitin sulfate and heparan sulfate proteoglycans has opposite effects on PTPRS oligomerization and regulation of neurite outgrowth (By similarity). Contributes to the inhibition of neurite and axonal outgrowth by chondroitin sulfate proteoglycans, also after nerve transection. Plays a role in stimulating neurite outgrowth in response to the heparan sulfate proteoglycan GPC2. Required for norm [...] (1924 aa)
SLC17A8MFS domain-containing protein. (587 aa)
GMFBGlia maturation factor; Belongs to the actin-binding proteins ADF family. GMF subfamily. (141 aa)
SYT7Synaptotagmin 7. (403 aa)
SPACA9Uncharacterized protein. (167 aa)
STX7t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (258 aa)
LOC776719Uncharacterized protein. (671 aa)
LOC422353Uncharacterized protein. (968 aa)
SV2BSynaptic vesicle glycoprotein 2B. (705 aa)
C1orf35Chromosome 1 open reading frame 35. (310 aa)
ENSGALP00000058230Uncharacterized protein. (317 aa)
MCTP2Multiple C2 and transmembrane domain containing 2. (895 aa)
KNL1Knl1_RWD_C domain-containing protein. (399 aa)
UVS.2LMetalloendopeptidase. (281 aa)
VTI1At-SNARE coiled-coil homology domain-containing protein. (224 aa)
TMEM230Transmembrane protein 230; Involved in trafficking and recycling of synaptic vesicles. Belongs to the TMEM134/TMEM230 family. (120 aa)
SYT15Uncharacterized protein. (416 aa)
SEPT2LSeptin-2; Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongat [...] (349 aa)
LAMP5Lysosomal associated membrane protein family member 5. (344 aa)
SYT11Synaptotagmin 11. (432 aa)
SPACA1Sperm acrosome associated 1. (197 aa)
HEXABeta-hexosaminidase. (631 aa)
SCAMP1Secretory carrier-associated membrane protein. (481 aa)
DNASE1Deoxyribonuclease-1; Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs. Expressed by non-hematopoietic tissues and preferentially cleaves protein-free DNA (By similarity). Among other functions, seems to be involved in cell death by apoptosis (By similarity). Binds specifically to G-actin and blocks actin polymerization (By similarity). (282 aa)
IFT20Intraflagellar transport 20. (132 aa)
POMCUncharacterized protein. (251 aa)
RAB10LUncharacterized protein. (208 aa)
GARSUncharacterized protein. (859 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (161 aa)
VPS33BUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (667 aa)
MFFMitochondrial fission factor. (252 aa)
CHGBChromogranin B. (673 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
EBAG9Uncharacterized protein. (336 aa)
SLC30A3Solute carrier family 30 member 3. (439 aa)
STXBP3Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (601 aa)
CCDC189Uncharacterized protein. (255 aa)
SFTPCBRICHOS domain-containing protein. (202 aa)
UNC13C-2Uncharacterized protein. (411 aa)
SCNN1DSodium channel epithelial 1 delta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
STK31Serine/threonine kinase 31. (1007 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (462 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
ENSGALP00000066467Uncharacterized protein. (248 aa)
RAB27ARab27a. (221 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (362 aa)
LGI3Leucine rich repeat LGI family member 3. (511 aa)
RAB15RAB15, member RAS oncogene family. (211 aa)
APBA1Amyloid beta precursor protein binding family A member 1. (824 aa)
SYTL3Synaptotagmin like 3. (620 aa)
STX19Syntaxin 19; Belongs to the syntaxin family. (291 aa)
HYAL6Hyaluronidase. (579 aa)
HYAL3Hyaluronidase. (584 aa)
STXBP5Syntaxin binding protein 5. (1152 aa)
ANXA11Annexin. (496 aa)
TSSK3Testis specific serine kinase 3. (268 aa)
SYTL1Uncharacterized protein. (806 aa)
DTNBP1Dysbindin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neuri [...] (369 aa)
ENSGALP00000068902Chorein_N domain-containing protein. (141 aa)
SYN2Synapsin_C domain-containing protein. (296 aa)
CAPN14Calpain 14; Belongs to the peptidase C2 family. (694 aa)
VPS13CVacuolar protein sorting 13 homolog C. (3587 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (176 aa)
SYCNSyncollin. (131 aa)
SNAP47Synaptosome associated protein 47. (461 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (245 aa)
SYNGR3MARVEL domain-containing protein. (295 aa)
KIAA1210DUF4592 domain-containing protein. (971 aa)
ENSGALP00000070006Synaptophysin. (351 aa)
GRPGastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (Probable). Stimulates pancreatic protein and fluid secretion, and increases acid secretion from the avian proventriculus. Belongs to the bombesin/neuromedin-B/ranatensin family. (164 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (823 aa)
TMED2GOLD domain-containing protein. (208 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons. (270 aa)
RAB3IL1Sec2p domain-containing protein. (376 aa)
ATP6V1AV-type proton ATPase catalytic subunit A; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. In aerobic conditions, involved in intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. May play a role in neurite development and synaptic connectivity. Belongs to the ATPase alpha/beta chains family. (617 aa)
ENSGALP00000070662Uncharacterized protein. (243 aa)
PHACTR2Phosphatase and actin regulator. (642 aa)
DNM1LUncharacterized protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (735 aa)
RAB2ARas-related protein Rab-2A; Required for protein transport from the endoplasmic reticulum to the Golgi complex; Belongs to the small GTPase superfamily. Rab family. (212 aa)
ENSGALP00000071604Uncharacterized protein. (406 aa)
IQUBIQ motif and ubiquitin domain containing. (704 aa)
BDNFBrain-derived neurotrophic factor; Important signaling molecule that activates signaling cascades downstream of NTRK2 (By similarity). During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including lo [...] (254 aa)
ITPR1Uncharacterized protein. (2800 aa)
APBA2Amyloid beta precursor protein binding family A member 2. (755 aa)
SYT10Synaptotagmin 10. (525 aa)
VPS13BUncharacterized protein. (511 aa)
RAB4ARAB4A, member RAS oncogene family. (255 aa)
SPATA1SPATA1_C domain-containing protein. (163 aa)
CBARPCACN subunit beta associated regulatory protein. (852 aa)
SV2ASynaptic vesicle glycoprotein 2A. (751 aa)
SYTL4Synaptotagmin like 4. (690 aa)
NGFBeta-nerve growth factor; Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. (284 aa)
MCTP1Multiple C2 and transmembrane domain containing 1. (954 aa)
CEP131Centrosomal protein 131. (1161 aa)
VAMP1V-SNARE coiled-coil homology domain-containing protein. (119 aa)
LOC112530958Uncharacterized protein. (149 aa)
ENSGALP00000074167Uncharacterized protein. (178 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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