(12 nodes) ATAC complex network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TADA3	Transcriptional adaptor 3. (498 aa)
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (804 aa)
	DR1	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity). (176 aa)
	KAT14	N-acetyltransferase domain-containing protein. (781 aa)
	ZZZ3	Uncharacterized protein. (905 aa)
	MBIP	MAP3K12 binding inhibitory protein 1. (352 aa)
	SGF29	SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. (293 aa)
	POLE3	CBFD_NFYB_HMF domain-containing protein. (143 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7. (643 aa)
	POLE4	DNA polymerase epsilon 4, accessory subunit. (146 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (808 aa)
	YEATS2	YEATS domain containing 2. (1398 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DR1	KAT14	ENSGALP00000009403	ENSGALP00000014153	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	N-acetyltransferase domain-containing protein.	0.807
DR1	KAT2A	ENSGALP00000009403	ENSGALP00000005317	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.725
DR1	KAT2B	ENSGALP00000009403	ENSGALP00000053796	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.722
DR1	MBIP	ENSGALP00000009403	ENSGALP00000016401	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	MAP3K12 binding inhibitory protein 1.	0.780
DR1	POLE3	ENSGALP00000009403	ENSGALP00000039553	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	CBFD_NFYB_HMF domain-containing protein.	0.924
DR1	SGF29	ENSGALP00000009403	ENSGALP00000037055	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me.	0.802
DR1	TADA3	ENSGALP00000009403	ENSGALP00000055576	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	Transcriptional adaptor 3.	0.795
DR1	YEATS2	ENSGALP00000009403	ENSGALP00000067137	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	YEATS domain containing 2.	0.810
DR1	ZZZ3	ENSGALP00000009403	ENSGALP00000014603	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	Uncharacterized protein.	0.699
KAT14	DR1	ENSGALP00000014153	ENSGALP00000009403	N-acetyltransferase domain-containing protein.	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	0.807
KAT14	KAT2A	ENSGALP00000014153	ENSGALP00000005317	N-acetyltransferase domain-containing protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.780
KAT14	KAT2B	ENSGALP00000014153	ENSGALP00000053796	N-acetyltransferase domain-containing protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.780
KAT14	MBIP	ENSGALP00000014153	ENSGALP00000016401	N-acetyltransferase domain-containing protein.	MAP3K12 binding inhibitory protein 1.	0.650
KAT14	POLE3	ENSGALP00000014153	ENSGALP00000039553	N-acetyltransferase domain-containing protein.	CBFD_NFYB_HMF domain-containing protein.	0.598
KAT14	SGF29	ENSGALP00000014153	ENSGALP00000037055	N-acetyltransferase domain-containing protein.	SAGA-associated factor 29; Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me.	0.992
KAT14	TADA3	ENSGALP00000014153	ENSGALP00000055576	N-acetyltransferase domain-containing protein.	Transcriptional adaptor 3.	0.913
KAT14	YEATS2	ENSGALP00000014153	ENSGALP00000067137	N-acetyltransferase domain-containing protein.	YEATS domain containing 2.	0.947
KAT14	ZZZ3	ENSGALP00000014153	ENSGALP00000014603	N-acetyltransferase domain-containing protein.	Uncharacterized protein.	0.946
KAT2A	DR1	ENSGALP00000005317	ENSGALP00000009403	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	Protein Dr1; The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own (By similarity).	0.725
KAT2A	KAT14	ENSGALP00000005317	ENSGALP00000014153	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	N-acetyltransferase domain-containing protein.	0.780