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HOXA11 | Homeobox protein Hox-A11; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; Belongs to the Abd-B homeobox family. (297 aa) | ||||
WNT11 | Protein Wnt-11; Ligand for members of the frizzled family of seven transmembrane receptors. May play a role in the formation of dermal structure, both limb and feather buds. Is likely to signal over only few cell diameters. (354 aa) | ||||
CD34 | CD34 molecule. (385 aa) | ||||
DVL1 | Dishevelled segment polarity protein 1. (529 aa) | ||||
GDNF | Glial cell derived neurotrophic factor. (209 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (240 aa) | ||||
ABL1 | Tyrosine-protein kinase. (1111 aa) | ||||
WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa) | ||||
SOX8 | Transcription factor SOX-8; May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'. (470 aa) | ||||
LHX1 | LIM/homeobox protein Lhx1; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with ISL-2. (406 aa) | ||||
NTN4L | Uncharacterized protein. (638 aa) | ||||
RYK | Receptor like tyrosine kinase. (481 aa) | ||||
LHX5 | LIM homeobox protein 5. (402 aa) | ||||
FRS2 | IRS-type PTB domain-containing protein. (508 aa) | ||||
DMRT3 | Doublesex and mab-3 related transcription factor 3. (466 aa) | ||||
AGT | Angiotensinogen; Belongs to the serpin family. (464 aa) | ||||
IHH | Indian hedgehog protein C-product; Intercellular signal essential for a variety of patterning events during development. Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. Implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones. Induces the expression of parathyroid hormone-related protein (PTHRP); Belongs to the hedgehog family. (408 aa) | ||||
NTN4 | Netrin 4. (626 aa) | ||||
DACT1 | DAPPER1. (822 aa) | ||||
AHI1 | Abelson helper integration site 1. (1242 aa) | ||||
MSX1 | Homeobox protein GHOX-7; Probably plays a role in patterning events during embryonic limb development. May also be involved in programmed cell death. (288 aa) | ||||
ROR2 | Receptor tyrosine kinase-like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (934 aa) | ||||
SIX4 | SIX homeobox 4. (776 aa) | ||||
FGF8 | Fibroblast growth factor 8; Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Involved in initiation, outgrowth and patterning of the limbs; Belongs to the heparin-binding growth factors family. (214 aa) | ||||
GREM1 | Gremlin-1; Cytokine that may play a role in the development of the medial pallium and during optic nerve and pecten development by modulating BMP signaling. (184 aa) | ||||
SOX9 | Transcription factor SOX-9; Transcription factor that selectively activates enhancer through its interaction with a DNA-binding partner factor. Activates enhancer of COL2A1 through its binding with DNA sequence 5'-ATTCAT-3'. In response to bone morphogenetic protein stimulus, phosphorylation is induced and then sumoylation, allowing cooperation with SNAI2 to trigger neural crest delamination. Functions at the level of mesenchymal cell condensation by inducing cartilage development in limbs and by changing the aggregation properties of limb mesenchymal cells. Regulates the cell fate dec [...] (494 aa) | ||||
WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (388 aa) | ||||
FGF7 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa) | ||||
SIX2 | Sine oculis-related homeobox 2 homolog. (287 aa) | ||||
FZD3 | Frizzled-3; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (666 aa) | ||||
DVL3 | Dishevelled segment polarity protein 3. (731 aa) | ||||
CTNNB1 | Uncharacterized protein. (781 aa) | ||||
AR | Uncharacterized protein. (703 aa) | ||||
SIX1 | Sine oculis-related homeobox 1 homolog. (282 aa) | ||||
SMO | Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). (816 aa) | ||||
HGF | Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (726 aa) | ||||
LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (952 aa) | ||||
SEC24B | Uncharacterized protein. (1234 aa) | ||||
HOXB7 | Homeobox B7. (217 aa) | ||||
SPRY1 | Protein sprouty homolog 1; May function as an antagonist of fibroblast growth factor (FGF) pathways and may negatively modulate respiratory organogenesis; Belongs to the sprouty family. (321 aa) | ||||
ABL2 | Tyrosine-protein kinase. (1159 aa) | ||||
RSPO2 | R-spondin 2. (241 aa) | ||||
SULF1 | Sulfatase 1. (862 aa) | ||||
TNFRSF11B | Tumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (402 aa) | ||||
AJAP1 | Adherens junctions associated protein 1. (266 aa) | ||||
MKS1 | MKS transition zone complex subunit 1. (562 aa) | ||||
CSF1 | Uncharacterized protein. (493 aa) | ||||
ENSGALP00000066589 | Uncharacterized protein. (349 aa) | ||||
NKD1 | NKD inhibitor of WNT signaling pathway 1. (472 aa) | ||||
ANKRD6 | Ankyrin repeat domain 6. (793 aa) | ||||
PKHD1 | Uncharacterized protein. (551 aa) | ||||
GATA3 | GATA-binding factor 3; Transcriptional activator which probably serves as a general switch factor for cell-specific development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of genes. (444 aa) | ||||
PTHLH | Parathyroid hormone-related protein; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport; Belongs to the parathyroid hormone family. (214 aa) | ||||
CTHRC1 | Collagen triple helix repeat containing 1. (314 aa) | ||||
ENSGALP00000069823 | Uncharacterized protein. (167 aa) | ||||
ENSGALP00000071132 | Uncharacterized protein. (386 aa) | ||||
BTBD7 | BTB domain containing 7. (1159 aa) | ||||
SP6 | Sp6 transcription factor. (357 aa) | ||||
SAPCD2 | Suppressor APC domain containing 2. (458 aa) | ||||
ENSGALP00000072166 | IPT/TIG domain-containing protein. (239 aa) | ||||
JHY | Junctional cadherin complex regulator. (741 aa) | ||||
ENSGALP00000072609 | Uncharacterized protein. (215 aa) | ||||
DAB2 | DAB adaptor protein 2. (715 aa) | ||||
HOXC11 | Homeobox C11. (193 aa) | ||||
ENSGALP00000074194 | Uncharacterized protein. (401 aa) |