Your Input: | |||||
ID2 | Transcriptional regulator Id2. (134 aa) | ||||
LRRK2 | Uncharacterized protein. (2557 aa) | ||||
FOXG1 | Forkhead box protein G1; May determine the nasotemporal axis of the retina, and consequently specify the topographical projection of the retinal ganglion-cell axons to the tectum by controlling expression of their target genes. (451 aa) | ||||
PTPRZ1 | Protein-tyrosine-phosphatase. (2343 aa) | ||||
KIAA1524 | Protein CIP2A homolog. (924 aa) | ||||
ZNF335 | Uncharacterized protein. (1473 aa) | ||||
CDH2 | Cadherin-2; Calcium-dependent cell adhesion protein; preferentially mediates homotypic cell-cell adhesion. Cadherins may thus contribute to the sorting of heterogeneous cell types, and thereby play an important role during embryonic development (By similarity). (912 aa) | ||||
VEGFC | Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (586 aa) | ||||
VAX1 | Ventral anterior homeobox 1; Transcription factor that plays a role in establishing dorsal-ventral polarity in the neural retina. (325 aa) | ||||
DLL4 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (709 aa) | ||||
SPINT1 | Uncharacterized protein. (509 aa) | ||||
LHX5 | LIM homeobox protein 5. (402 aa) | ||||
DRD2 | Dopamine receptor 2 protein transcript variant 1; Belongs to the G-protein coupled receptor 1 family. (437 aa) | ||||
SHH | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity). Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity). Both activities occur in the reticulum endoplasmic (By similarity). Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity). (425 aa) | ||||
LHX1 | LIM/homeobox protein Lhx1; Transcriptional factor that defines subclasses of motoneurons that segregate into columns in the spinal cord and select distinct axon pathways. Acts in conjunction with ISL-2. (406 aa) | ||||
DISP3 | Protein dispatched homolog 3; Plays a role in neuronal proliferation and differentiation (By similarity). Plays a role in the accumulation of cellular cholesterol. Involved in intracellular lipid droplet formation. May contribute to cholesterol homeostasis in neuronal cells. (1338 aa) | ||||
SHCBP1 | SHC binding and spindle associated 1. (650 aa) | ||||
TRIM71 | E3 ubiquitin-protein ligase TRIM71; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and participates in post-transcriptional repression of transcripts. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development. Belongs to the TRIM/RBCC family. (877 aa) | ||||
ID4 | BHLH domain-containing protein. (139 aa) | ||||
CX3CR1 | C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (354 aa) | ||||
SIX3 | Homeobox protein SIX3; Transcriptional regulator which can act as both a transcriptional repressor and activator by binding a ATTA homeodomain core recognition sequence on these target genes. During forebrain development represses WNT1 expression allowing zona limitans intrathalamica formation and thereby ensuring proper anterio-posterior patterning of the diencephalon and formation of the rostral diencephalon. Acts as a direct upstream activator of SHH expression in the rostral diencephalon ventral midline and that in turn SHH maintains its expression. In addition, Six3 activity is re [...] (314 aa) | ||||
ENSGALP00000058848 | Uncharacterized protein. (236 aa) | ||||
ENSGALP00000060974 | LIM zinc-binding domain-containing protein. (209 aa) | ||||
KIFAP3 | Kinesin associated protein 3. (793 aa) | ||||
ENSGALP00000062901 | Uncharacterized protein. (229 aa) | ||||
ENSGALP00000064942 | Uncharacterized protein. (152 aa) | ||||
TOX | Thymocyte selection associated high mobility group box. (525 aa) | ||||
ENSGALP00000068660 | Uncharacterized protein. (221 aa) | ||||
TAFA3 | TAFA chemokine like family member 3. (136 aa) | ||||
NF2L | FERM domain-containing protein. (648 aa) | ||||
LIMS2 | LIM zinc finger domain containing 2. (252 aa) | ||||
TAFA1 | TAFA chemokine like family member 1. (145 aa) | ||||
BTG2 | BTG anti-proliferation factor 2. (164 aa) | ||||
PTBP2 | Polypyrimidine tract binding protein 2. (675 aa) | ||||
NF2 | FERM domain-containing protein. (595 aa) | ||||
DCT | L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (521 aa) | ||||
CX3CL1 | SCY domain-containing protein. (496 aa) | ||||
OTP | Orthopedia homeobox. (325 aa) | ||||
APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (671 aa) | ||||
FZD3 | Frizzled-3; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...] (666 aa) | ||||
ENSGALP00000044096 | Uncharacterized protein. (239 aa) | ||||
SIRT2 | Deacetylase sirtuin-type domain-containing protein. (485 aa) | ||||
CTNNB1 | Uncharacterized protein. (781 aa) | ||||
CEND1 | Uncharacterized protein. (130 aa) | ||||
LYN | Tyrosine-protein kinase. (491 aa) | ||||
LIMS1 | LIM domain-containing protein. (362 aa) | ||||
CDH15 | Cadherin 15; Cadherins are calcium-dependent cell adhesion proteins. (792 aa) | ||||
KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (826 aa) | ||||
DISC1 | DISC1 scaffold protein. (856 aa) | ||||
ILK | Integrin-linked kinase. (452 aa) | ||||
SMO | Smoothened homolog; G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). (816 aa) | ||||
ADGRG1 | Adhesion G protein-coupled receptor G1; Belongs to the G-protein coupled receptor 2 family. (695 aa) | ||||
SMAD6 | Mothers against decapentaplegic homolog 6; Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling, preventing NF-kappa-B activation, and BMP-SMAD1 signaling pathway. Binds to regulatory elements in target promoter regions (By similarity). (431 aa) |