(22 nodes) Regulation of T cell migration network (Gallus gallus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	CCL5	C-C motif chemokine. (90 aa)
	ITGB3	Integrin beta; Belongs to the integrin beta chain family. (781 aa)
	SPNS2	Sphingolipid transporter 2. (510 aa)
	CCL20	C-C motif chemokine. (100 aa)
	ABL1	Tyrosine-protein kinase. (1111 aa)
	ADAM10	Uncharacterized protein. (749 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (193 aa)
	APOD	Apolipoprotein D; Belongs to the calycin superfamily. Lipocalin family. (189 aa)
	FADD	Fas associated via death domain. (195 aa)
	DOCK8	Dedicator of cytokinesis 8; Belongs to the DOCK family. (2036 aa)
	XCL1	Lymphotactin. (97 aa)
	CD200	Uncharacterized protein. (254 aa)
	ADAM17	Tumor necrosis factor alpha converting enzyme. (829 aa)
	APP	BPTI/Kunitz inhibitor domain-containing protein. (751 aa)
	FAM65B	Rho family-interacting cell polarization regulator 2; Acts as an inhibitor of the small GTPase RHOA and plays several roles in the regulation of myoblast and hair cell differentiation, lymphocyte T proliferation and neutrophil polarization. Plays a role in fetal mononuclear myoblast differentiation by promoting filopodia and myotube formation. Maintains naive T lymphocytes in a quiescent state and prevents chemokine-induced T lymphocyte responses, such as cell adhesion, polarization and migration. Involved also in the regulation of neutrophil polarization, chemotaxis and adhesion. Requ [...] (1067 aa)
	ABL2	Tyrosine-protein kinase. (1159 aa)
	ITGA4	Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1021 aa)
	STK39	Serine/threonine kinase 39. (615 aa)
	ENSGALP00000066325	Uncharacterized protein. (71 aa)
	CCL19	C-C motif chemokine. (108 aa)
	CD99L2	CD99 molecule like 2. (419 aa)
	OXSR1	Oxidative stress responsive kinase 1. (533 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	ABL2	ENSGALP00000006154	ENSGALP00000052767	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.907
ABL1	CRKL	ENSGALP00000006154	ENSGALP00000010305	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.971
ABL2	ABL1	ENSGALP00000052767	ENSGALP00000006154	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.907
ABL2	CRKL	ENSGALP00000052767	ENSGALP00000010305	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.964
ADAM10	ADAM17	ENSGALP00000006687	ENSGALP00000030970	Uncharacterized protein.	Tumor necrosis factor alpha converting enzyme.	0.462
ADAM10	APP	ENSGALP00000006687	ENSGALP00000036014	Uncharacterized protein.	BPTI/Kunitz inhibitor domain-containing protein.	0.635
ADAM17	ADAM10	ENSGALP00000030970	ENSGALP00000006687	Tumor necrosis factor alpha converting enzyme.	Uncharacterized protein.	0.462
ADAM17	APP	ENSGALP00000030970	ENSGALP00000036014	Tumor necrosis factor alpha converting enzyme.	BPTI/Kunitz inhibitor domain-containing protein.	0.433
APP	ADAM10	ENSGALP00000036014	ENSGALP00000006687	BPTI/Kunitz inhibitor domain-containing protein.	Uncharacterized protein.	0.635
APP	ADAM17	ENSGALP00000036014	ENSGALP00000030970	BPTI/Kunitz inhibitor domain-containing protein.	Tumor necrosis factor alpha converting enzyme.	0.433
CCL19	CCL20	ENSGALP00000068348	ENSGALP00000004738	C-C motif chemokine.	C-C motif chemokine.	0.901
CCL19	CCL5	ENSGALP00000068348	ENSGALP00000049143	C-C motif chemokine.	C-C motif chemokine.	0.988
CCL19	XCL1	ENSGALP00000068348	ENSGALP00000024539	C-C motif chemokine.	Lymphotactin.	0.903
CCL20	CCL19	ENSGALP00000004738	ENSGALP00000068348	C-C motif chemokine.	C-C motif chemokine.	0.901
CCL20	CCL5	ENSGALP00000004738	ENSGALP00000049143	C-C motif chemokine.	C-C motif chemokine.	0.905
CCL20	XCL1	ENSGALP00000004738	ENSGALP00000024539	C-C motif chemokine.	Lymphotactin.	0.592
CCL5	CCL19	ENSGALP00000049143	ENSGALP00000068348	C-C motif chemokine.	C-C motif chemokine.	0.988
CCL5	CCL20	ENSGALP00000049143	ENSGALP00000004738	C-C motif chemokine.	C-C motif chemokine.	0.905
CCL5	XCL1	ENSGALP00000049143	ENSGALP00000024539	C-C motif chemokine.	Lymphotactin.	0.938
CRKL	ABL1	ENSGALP00000010305	ENSGALP00000006154	CRK like proto-oncogene, adaptor protein.	Tyrosine-protein kinase.	0.971