(18 nodes) Rough endoplasmic reticulum membrane network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCDC47	Coiled-coil domain containing 47. (481 aa)
	TMEM57	Uncharacterized protein. (662 aa)
	PLOD1	Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links. (730 aa)
	TMEM97	Transmembrane protein 97; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. (171 aa)
	SEC61A1	SEC61 translocon alpha 1 subunit. (476 aa)
	SRPRB	Uncharacterized protein. (258 aa)
	SEC62	Translocation protein SEC62; Required for preprotein translocation. (398 aa)
	SEC61B	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
	SEC63	SEC63 homolog, protein translocation regulator. (755 aa)
	EPM2A	Laforin. (319 aa)
	RPL27	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family. (216 aa)
	ARL6IP1	Uncharacterized protein. (203 aa)
	SEC61A2	Plug_translocon domain-containing protein. (476 aa)
	RPS26	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family. (115 aa)
	SEC61G	Uncharacterized protein. (68 aa)
	RPS15A	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family. (130 aa)
	RPS28	Uncharacterized protein. (69 aa)
	SRPRA	Uncharacterized protein. (676 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL6IP1	RPL27	ENSGALP00000044389	ENSGALP00000038957	Uncharacterized protein.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.980
ARL6IP1	RPS15A	ENSGALP00000044389	ENSGALP00000066249	Uncharacterized protein.	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.	0.868
ARL6IP1	RPS26	ENSGALP00000044389	ENSGALP00000052582	Uncharacterized protein.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.978
ARL6IP1	RPS28	ENSGALP00000044389	ENSGALP00000070639	Uncharacterized protein.	Uncharacterized protein.	0.986
ARL6IP1	SEC61A1	ENSGALP00000044389	ENSGALP00000009577	Uncharacterized protein.	SEC61 translocon alpha 1 subunit.	0.960
ARL6IP1	SEC61A2	ENSGALP00000044389	ENSGALP00000045021	Uncharacterized protein.	Plug_translocon domain-containing protein.	0.960
ARL6IP1	SEC61B	ENSGALP00000044389	ENSGALP00000022049	Uncharacterized protein.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.835
ARL6IP1	SEC61G	ENSGALP00000044389	ENSGALP00000060425	Uncharacterized protein.	Uncharacterized protein.	0.772
ARL6IP1	SRPRA	ENSGALP00000044389	ENSGALP00000072364	Uncharacterized protein.	Uncharacterized protein.	0.445
CCDC47	RPL27	ENSGALP00000000782	ENSGALP00000038957	Coiled-coil domain containing 47.	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	0.642
CCDC47	SEC61A1	ENSGALP00000000782	ENSGALP00000009577	Coiled-coil domain containing 47.	SEC61 translocon alpha 1 subunit.	0.700
CCDC47	SEC61A2	ENSGALP00000000782	ENSGALP00000045021	Coiled-coil domain containing 47.	Plug_translocon domain-containing protein.	0.701
CCDC47	SEC61B	ENSGALP00000000782	ENSGALP00000022049	Coiled-coil domain containing 47.	Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.	0.729
CCDC47	SEC61G	ENSGALP00000000782	ENSGALP00000060425	Coiled-coil domain containing 47.	Uncharacterized protein.	0.712
RPL27	ARL6IP1	ENSGALP00000038957	ENSGALP00000044389	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	Uncharacterized protein.	0.980
RPL27	CCDC47	ENSGALP00000038957	ENSGALP00000000782	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	Coiled-coil domain containing 47.	0.642
RPL27	RPS15A	ENSGALP00000038957	ENSGALP00000066249	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	Ribosomal protein S15a; Belongs to the universal ribosomal protein uS8 family.	0.996
RPL27	RPS26	ENSGALP00000038957	ENSGALP00000052582	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.	0.999
RPL27	RPS28	ENSGALP00000038957	ENSGALP00000070639	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	Uncharacterized protein.	0.999
RPL27	SEC61A1	ENSGALP00000038957	ENSGALP00000009577	60S ribosomal protein L27; Belongs to the eukaryotic ribosomal protein eL27 family.	SEC61 translocon alpha 1 subunit.	0.722