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GPR143 | Uncharacterized protein. (391 aa) | ||||
DTNBP1 | Dysbindin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neuri [...] (369 aa) | ||||
SYTL1 | Uncharacterized protein. (806 aa) | ||||
GCHFR | Uncharacterized protein. (84 aa) | ||||
LOC776376 | Ig-like domain-containing protein. (310 aa) | ||||
LOC422353 | Uncharacterized protein. (968 aa) | ||||
GSN | Gelsolin; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). (833 aa) | ||||
CNP | Uncharacterized protein. (534 aa) | ||||
PMEL | Melanocyte protein PMEL; Might be required for polymerization of melanin onto the core structure of melanosomes with enzymic function of tyrosinase; Belongs to the PMEL/NMB family. (740 aa) | ||||
SEC22B | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER. (215 aa) | ||||
CAPG | Capping actin protein, gelsolin like. (327 aa) | ||||
SYTL2 | Synaptotagmin like 2. (863 aa) | ||||
ABCB6 | ATP binding cassette subfamily B member 6 (Langereis blood group). (894 aa) | ||||
SLC45A4 | Solute carrier family 45 member 4. (787 aa) | ||||
RAB38 | RAB38, member RAS oncogene family. (212 aa) | ||||
TYRP1 | 5,6-dihydroxyindole-2-carboxylic acid oxidase; Plays a role in melanin biosynthesis. Catalyzes the oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6- quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. Also to a lower extent, capable of hydroxylating tyrosine and producing melanin. (536 aa) | ||||
DCT | L-dopachrome tautomerase; Catalyzes the conversion of L-dopachrome into 5,6- dihydroxyindole-2-carboxylic acid (DHICA). Involved in regulating eumelanin and phaeomelanin levels. (521 aa) | ||||
MLANA | Melan-A. (113 aa) | ||||
TYR | Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. (537 aa) | ||||
MMP1 | Matrix metallopeptidase 1. (466 aa) | ||||
OCA2 | OCA2 melanosomal transmembrane protein. (726 aa) | ||||
PDIA6 | Protein disulfide isomerase family A member 6; Belongs to the protein disulfide isomerase family. (447 aa) | ||||
TMEM33 | Transmembrane protein 33. (251 aa) | ||||
RAB32 | Uncharacterized protein. (218 aa) | ||||
TFRC | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Belongs to the peptidase M28 family. M28B subfamily. (776 aa) | ||||
ABCC2 | Uncharacterized protein. (1538 aa) | ||||
PLSCR5 | Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (263 aa) | ||||
CTNS | Cystinosin, lysosomal cystine transporter. (377 aa) | ||||
MREG | Melanoregulin. (208 aa) | ||||
SLC45A2 | Uncharacterized protein. (543 aa) | ||||
MFSD12 | Major facilitator superfamily domain containing 12. (494 aa) |