STRINGSTRING
ASPN ASPN LRRC52 LRRC52 GP9 GP9 OMG OMG FLRT3 FLRT3 RXFP1 RXFP1 LGR5 LGR5 FLRT2 FLRT2 EPYC EPYC LUM LUM CHAD CHAD LRTM2 LRTM2 FMOD FMOD PRELP PRELP LGR4 LGR4 LINGO3 LINGO3 DCN DCN KERA KERA LRRC3B LRRC3B NTRK2 NTRK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ASPNAsporin. (371 aa)
LRRC52Leucine rich repeat containing 52. (294 aa)
GP9Glycoprotein IX platelet. (208 aa)
OMGOligodendrocyte myelin glycoprotein. (434 aa)
FLRT3Leucine-rich repeat transmembrane protein FLRT3; Modulates the structure and function of the apical ectodermal ridge (AER) that controls embryonic limb development. Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development. Plays a role in cell-cell adhesion via its interaction with latrophilins that are expressed at the surface of adjacent cells. Mediates axon attraction towards cells expressing NTN1. M [...] (647 aa)
RXFP1Relaxin family peptide receptor 1. (763 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (909 aa)
FLRT2Fibronectin leucine rich transmembrane protein 2. (662 aa)
EPYCEpiphycan; May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. (316 aa)
LUMLumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (343 aa)
CHADUncharacterized protein. (361 aa)
LRTM2Leucine rich repeats and transmembrane domains 2. (460 aa)
FMODFibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (380 aa)
PRELPProline and arginine rich end leucine rich repeat protein. (430 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (952 aa)
LINGO3Leucine rich repeat and Ig domain containing 3. (605 aa)
DCNDecorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (357 aa)
KERAKeratocan; Plays an important role in generating and maintaining a transparent matrix within the corneal stroma. (353 aa)
LRRC3BLeucine rich repeat containing 3B. (259 aa)
NTRK2BDNF/NT-3 growth factors receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, [...] (842 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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