(11 nodes) Guanine nucleotide binding protein (G-protein), alpha subunit network (Gallus gallus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	GNAO1	Uncharacterized protein. (354 aa)
	GNA11	Guanine nucleotide-binding protein G11 alpha-subunit. (359 aa)
	GNAZ	G protein subunit alpha z. (355 aa)
	GNAT3	Uncharacterized protein. (354 aa)
	GNAL	Uncharacterized protein. (379 aa)
	GNAQ	Uncharacterized protein. (359 aa)
	GNAI1	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...] (354 aa)
	GNA13	G protein subunit alpha 13. (377 aa)
	GNAT2	Uncharacterized protein. (354 aa)
	GNAI3	G protein alpha subunit. (354 aa)
	GNAS	Guanine nucleotide-binding protein G(S) subunit alpha XL. (417 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GNA11	GNA13	ENSGALP00000005115	ENSGALP00000055111	Guanine nucleotide-binding protein G11 alpha-subunit.	G protein subunit alpha 13.	0.614
GNA11	GNAI1	ENSGALP00000005115	ENSGALP00000044195	Guanine nucleotide-binding protein G11 alpha-subunit.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.574
GNA11	GNAI3	ENSGALP00000005115	ENSGALP00000062750	Guanine nucleotide-binding protein G11 alpha-subunit.	G protein alpha subunit.	0.568
GNA11	GNAL	ENSGALP00000005115	ENSGALP00000022345	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.586
GNA11	GNAO1	ENSGALP00000005115	ENSGALP00000004997	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.567
GNA11	GNAQ	ENSGALP00000005115	ENSGALP00000024446	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.902
GNA11	GNAS	ENSGALP00000005115	ENSGALP00000066357	Guanine nucleotide-binding protein G11 alpha-subunit.	Guanine nucleotide-binding protein G(S) subunit alpha XL.	0.619
GNA11	GNAT2	ENSGALP00000005115	ENSGALP00000058253	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.560
GNA11	GNAT3	ENSGALP00000005115	ENSGALP00000013713	Guanine nucleotide-binding protein G11 alpha-subunit.	Uncharacterized protein.	0.562
GNA11	GNAZ	ENSGALP00000005115	ENSGALP00000010857	Guanine nucleotide-binding protein G11 alpha-subunit.	G protein subunit alpha z.	0.560
GNA13	GNA11	ENSGALP00000055111	ENSGALP00000005115	G protein subunit alpha 13.	Guanine nucleotide-binding protein G11 alpha-subunit.	0.614
GNA13	GNAI1	ENSGALP00000055111	ENSGALP00000044195	G protein subunit alpha 13.	Guanine nucleotide-binding protein G(i) subunit alpha-1; Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Signaling by an activated GPCR promotes GDP release and GTP binding. The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal. Both GDP release and GTP hydrolysis are modulated by numer [...]	0.586
GNA13	GNAI3	ENSGALP00000055111	ENSGALP00000062750	G protein subunit alpha 13.	G protein alpha subunit.	0.595
GNA13	GNAL	ENSGALP00000055111	ENSGALP00000022345	G protein subunit alpha 13.	Uncharacterized protein.	0.660
GNA13	GNAO1	ENSGALP00000055111	ENSGALP00000004997	G protein subunit alpha 13.	Uncharacterized protein.	0.585
GNA13	GNAQ	ENSGALP00000055111	ENSGALP00000024446	G protein subunit alpha 13.	Uncharacterized protein.	0.622
GNA13	GNAS	ENSGALP00000055111	ENSGALP00000066357	G protein subunit alpha 13.	Guanine nucleotide-binding protein G(S) subunit alpha XL.	0.667
GNA13	GNAT2	ENSGALP00000055111	ENSGALP00000058253	G protein subunit alpha 13.	Uncharacterized protein.	0.581
GNA13	GNAT3	ENSGALP00000055111	ENSGALP00000013713	G protein subunit alpha 13.	Uncharacterized protein.	0.581
GNA13	GNAZ	ENSGALP00000055111	ENSGALP00000010857	G protein subunit alpha 13.	G protein subunit alpha z.	0.563