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| | LRRC18 | Leucine rich repeat containing 18. (259 aa) |
| | LRRC38 | Leucine rich repeat containing 38. (293 aa) |
| | SKP2 | F-box domain-containing protein. (520 aa) |
| | LRRC52 | Leucine rich repeat containing 52. (294 aa) |
| | FBXL8 | F-box domain-containing protein. (379 aa) |
| | LRRC45 | Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion. (670 aa) |
| | LINGO1 | Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (By similarity). (558 aa) |
| | LRRTM2 | Leucine rich repeat transmembrane neuronal 2. (515 aa) |
| | TSKU | Tsukushin; Dorsalizing factor involved in the induction of Hensen node. Functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation. (369 aa) |
| | LRRTM4 | Leucine rich repeat transmembrane neuronal 4. (590 aa) |
| | LUM | Lumican; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (343 aa) |
| | EPYC | Epiphycan; May have a role in bone formation and also in establishing the ordered structure of cartilage through matrix organization; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. (316 aa) |
| | ZYG11A | Zyg-11 family member B, cell cycle regulator. (735 aa) |
| | FLRT2 | Fibronectin leucine rich transmembrane protein 2. (662 aa) |
| | CNOT6L | CCR4-NOT transcription complex subunit 6 like. (607 aa) |
| | FBXO33 | F-box protein 33. (526 aa) |
| | LGR5 | Leucine rich repeat containing G protein-coupled receptor 5. (909 aa) |
| | LRFN2 | Leucine rich repeat and fibronectin type III domain containing 2. (763 aa) |
| | RXFP1 | Relaxin family peptide receptor 1. (763 aa) |
| | TLR5 | TLR5; Belongs to the Toll-like receptor family. (861 aa) |
| | SLITRK2 | SLIT and NTRK like family member 2. (857 aa) |
| | FSHR | Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (704 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (728 aa) |
| | LMOD2 | Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcomere organization in the heart, and for normal heart function (By similarity); Belongs to the tropomodulin family. (552 aa) |
| | SHOC2 | Leucine-rich repeat protein SHOC-2; Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes (By similarity); Belongs to the SHOC2 family. (582 aa) |
| | FLRT3 | Leucine-rich repeat transmembrane protein FLRT3; Modulates the structure and function of the apical ectodermal ridge (AER) that controls embryonic limb development. Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development. Plays a role in cell-cell adhesion via its interaction with latrophilins that are expressed at the surface of adjacent cells. Mediates axon attraction towards cells expressing NTN1. M [...] (647 aa) |
| | ANP32A | LRRcap domain-containing protein. (291 aa) |
| | RTN4R | Reticulon 4 receptor. (483 aa) |
| | SNRPA1 | LRRcap domain-containing protein. (255 aa) |
| | ADGRA1 | Adhesion G protein-coupled receptor A1; Belongs to the G-protein coupled receptor 2 family. (1303 aa) |
| | TLR4 | Toll-like receptor 4; Belongs to the Toll-like receptor family. (843 aa) |
| | LRRC75B | Uncharacterized protein. (336 aa) |
| | LRRC8B | Leucine rich repeat containing 8 VRAC subunit B. (800 aa) |
| | OMG | Oligodendrocyte myelin glycoprotein. (434 aa) |
| | GP9 | Glycoprotein IX platelet. (208 aa) |
| | ASPN | Asporin. (371 aa) |
| | TMOD3 | Uncharacterized protein. (352 aa) |
| | ZER1 | Zyg-11 related cell cycle regulator. (766 aa) |
| | FBXL18 | F-box domain-containing protein. (711 aa) |
| | LRRC40 | Leucine-rich repeat-containing protein 40. (603 aa) |
| | ATP5S | Uncharacterized protein. (199 aa) |
| | ELFN2 | Extracellular leucine rich repeat and fibronectin type III domain containing 2. (808 aa) |
| | NTRK1 | High affinity nerve growth factor receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and peripheral nervous systems through regulation of proliferation, differentiation and survival of sympathetic and nervous neurons. High affinity receptor for NGF which is its primary ligand, it can also bind and be activated by NTF3/neurotrophin-3. Upon dimeric NGF ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, phosphorylates and/or activates several downstream effectors that regulate distinct overlapping signali [...] (790 aa) |
| | TLR3 | Toll-like receptor 3; Belongs to the Toll-like receptor family. (896 aa) |
| | LRRC2 | Leucine rich repeat containing 2. (372 aa) |
| | E1C5R1_CHICK | Uncharacterized protein. (512 aa) |
| | CEP78 | Centrosomal protein 78. (796 aa) |
| | LRRC1 | Leucine rich repeat containing 1. (797 aa) |
| | SLITRK1 | SLIT and NTRK like family member 1. (692 aa) |
| | TBCEL | Ubiquitin-like domain-containing protein. (424 aa) |
| | CHAD | Uncharacterized protein. (361 aa) |
| | LRRC8D | Leucine rich repeat containing 8 VRAC subunit D. (856 aa) |
| | PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1. (1552 aa) |
| | TLR2B | Toll-like receptor 2 type-2; Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Mediates the response to mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2). (781 aa) |
| | LRTM2 | Leucine rich repeats and transmembrane domains 2. (460 aa) |
| | OGN | Mimecan; Induces bone formation in conjunction with TGF-beta-1 or TGF- beta-2; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class III subfamily. (294 aa) |
| | STK11IP | Serine/threonine-protein kinase 11-interacting protein. (1141 aa) |
| | FMOD | Fibromodulin; Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity); Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily. (380 aa) |
| | LRRC8A | Leucine rich repeat containing 8 VRAC subunit A. (810 aa) |
| | FBXL4 | F-box and leucine rich repeat protein 4. (620 aa) |
| | KDM2A | Lysine demethylase 2A. (1272 aa) |
| | LRRC20 | Uncharacterized protein. (183 aa) |
| | LRFN3 | Uncharacterized protein. (626 aa) |
| | RXFP2 | G_PROTEIN_RECEP_F1_2 domain-containing protein. (709 aa) |
| | PPP1R7 | LRRcap domain-containing protein. (354 aa) |
| | NTRK3 | NT-3 growth factor receptor; Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation (By similarity). The KT and KD isoforms fail to stimulate transformation, process outgrowth or survival. Isoform KI25 exhibits tyrosine phosphorylation in the absence of ligand and is unable to mediate survival of neuronal cells. Belongs to the [...] (852 aa) |
| | PRELP | Proline and arginine rich end leucine rich repeat protein. (430 aa) |
| | LGR4 | Leucine rich repeat containing G protein-coupled receptor 4. (952 aa) |
| | TLR2A | Toll-like receptor 2 type-1; Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). Does not respond to LPS and responds with less ability than TLR2-2 to mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2). (955 aa) |
| | LRRC30 | Uncharacterized protein. (298 aa) |
| | CMIP | C-Maf inducing protein. (678 aa) |
| | FBXO39 | F-box protein 39. (402 aa) |
| | FBXL7 | F-box and leucine rich repeat protein 7. (491 aa) |
| | LRRN1 | Leucine-rich repeat neuronal 1. (716 aa) |
| | NOD1 | Uncharacterized protein. (951 aa) |
| | PPP1R42 | Protein phosphatase 1 regulatory subunit 42. (320 aa) |
| | TMOD2 | Tropomodulin 2. (351 aa) |
| | LRRC59 | Leucine-rich repeat-containing protein 59; Required for nuclear import of FGF1. (361 aa) |
| | DRC3 | Dynein regulatory complex subunit 3. (522 aa) |
| | FBXL21 | F-box domain-containing protein. (437 aa) |
| | FBXL14 | F-box and leucine rich repeat protein 14. (400 aa) |
| | LRRC28 | Uncharacterized protein. (388 aa) |
| | LINGO3 | Leucine rich repeat and Ig domain containing 3. (605 aa) |
| | DCN | Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (357 aa) |
| | ANP32B | Acidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity). (262 aa) |
| | LRRC57 | Uncharacterized protein. (238 aa) |
| | RSU1 | Uncharacterized protein. (277 aa) |
| | KERA | Keratocan; Plays an important role in generating and maintaining a transparent matrix within the corneal stroma. (353 aa) |
| | LGI1 | LRRCT domain-containing protein. (543 aa) |
| | TLR1B | Toll-like receptor 1 type 2; Belongs to the Toll-like receptor family. (652 aa) |
| | LRRC3B | Leucine rich repeat containing 3B. (259 aa) |
| | LRRC17 | p37NB protein. (437 aa) |
| | FBXL3 | F-box and leucine rich repeat protein 3. (433 aa) |
| | NTRK2 | BDNF/NT-3 growth factors receptor; Receptor tyrosine kinase involved in the development and the maturation of the central and the peripheral nervous systems through regulation of neuron survival, proliferation, migration, differentiation, and synapse formation and plasticity. Receptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2. Upon ligand-binding, undergoes homodimerization, autophosphorylation and activation. Recruits, [...] (842 aa) |
| | LRRC4C | Leucine rich repeat containing 4C. (638 aa) |
| | LRRC8C | Leucine rich repeat containing 8 VRAC subunit C. (802 aa) |
| | TLR7 | Toll-like receptor 7; Belongs to the Toll-like receptor family. (1059 aa) |
| | GP1BB | Glycoprotein Ib platelet subunit beta. (202 aa) |
| | ANP32E | Acidic leucine-rich nuclear phosphoprotein 32 family member E; Histone chaperone that specifically mediates the genome-wide removal of histone H2A.Z/H2AZ1 from the nucleosome: removes H2A.Z/H2AZ1 from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AZ1 in the nucleosome. May stabilize the evicted H2A.Z/H2AZ1-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state. Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar [...] (282 aa) |
