STRINGSTRING
BACH2 BACH2 RHOBTB1 RHOBTB1 BTBD1 BTBD1 BTBD3 BTBD3 RBX1 RBX1 RHOBTB3 RHOBTB3 CISH CISH BTBD6 BTBD6 CUL1 CUL1 RHOBTB2 RHOBTB2 CUL2 CUL2 CACUL1 CACUL1 TCEB1 TCEB1 ZBTB7A ZBTB7A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BACH2BTB domain and CNC homolog 2. (850 aa)
RHOBTB1Uncharacterized protein. (694 aa)
BTBD1BTB domain-containing protein. (376 aa)
BTBD3BTB domain containing 3. (520 aa)
RBX1RING-type domain-containing protein. (108 aa)
RHOBTB3Rho related BTB domain containing 3. (618 aa)
CISHCytokine-inducible SH2-containing protein; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. CIS is involved in the negative regulation of cytokines that signal through the JAK-STAT5 pathway such as erythropoietin, prolactin and interleukin 3 (IL3) receptor. Inhibits STAT5 trans-activation by suppressing its tyrosine phosphorylation. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasom [...] (258 aa)
BTBD6BTB domain containing 6. (530 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
RHOBTB2Rho related BTB domain containing 2. (362 aa)
CUL2CULLIN_2 domain-containing protein; Belongs to the cullin family. (774 aa)
CACUL1Cullin domain-containing protein; Belongs to the cullin family. (377 aa)
TCEB1Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (112 aa)
ZBTB7AZinc finger and BTB domain-containing protein 7A; Transcription factor that represses the transcription of a wide range of genes involved in cell proliferation and differentiation. Directly and specifically binds to the consensus sequence 5'- [GA][CA]GACCCCCCCCC-3' and represses transcription both by regulating the organization of chromatin and through the direct recruitment of transcription factors to gene regulatory regions (By similarity). May also play a role, independently of its transcriptional activity, in double-strand break repair via classical non-homologous end joining/cNHEJ [...] (753 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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