(7 nodes) (2006) Rad54: the Swiss Army knife of homologous recombination? network (Gallus gallus)

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Your Input:
	LIG4	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. (912 aa)
	BRCA2	Tower domain-containing protein. (3397 aa)
	RAD50	Zinc-hook domain-containing protein. (1313 aa)
	RAD51C	RAD51 paralog C. (360 aa)
	EXO1	Uncharacterized protein. (800 aa)
	RAD52	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity). (422 aa)
	RAD51B	RAD51 paralog B. (415 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA2	EXO1	ENSGALP00000027524	ENSGALP00000017465	Tower domain-containing protein.	Uncharacterized protein.	0.967
BRCA2	LIG4	ENSGALP00000027524	ENSGALP00000027179	Tower domain-containing protein.	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	0.880
BRCA2	RAD50	ENSGALP00000027524	ENSGALP00000039135	Tower domain-containing protein.	Zinc-hook domain-containing protein.	0.608
BRCA2	RAD51B	ENSGALP00000027524	ENSGALP00000068967	Tower domain-containing protein.	RAD51 paralog B.	0.988
BRCA2	RAD51C	ENSGALP00000027524	ENSGALP00000048159	Tower domain-containing protein.	RAD51 paralog C.	0.998
BRCA2	RAD52	ENSGALP00000027524	ENSGALP00000063584	Tower domain-containing protein.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.978
EXO1	BRCA2	ENSGALP00000017465	ENSGALP00000027524	Uncharacterized protein.	Tower domain-containing protein.	0.967
EXO1	LIG4	ENSGALP00000017465	ENSGALP00000027179	Uncharacterized protein.	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	0.925
EXO1	RAD50	ENSGALP00000017465	ENSGALP00000039135	Uncharacterized protein.	Zinc-hook domain-containing protein.	0.884
EXO1	RAD51B	ENSGALP00000017465	ENSGALP00000068967	Uncharacterized protein.	RAD51 paralog B.	0.953
EXO1	RAD51C	ENSGALP00000017465	ENSGALP00000048159	Uncharacterized protein.	RAD51 paralog C.	0.944
EXO1	RAD52	ENSGALP00000017465	ENSGALP00000063584	Uncharacterized protein.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.982
LIG4	BRCA2	ENSGALP00000027179	ENSGALP00000027524	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	Tower domain-containing protein.	0.880
LIG4	EXO1	ENSGALP00000027179	ENSGALP00000017465	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	Uncharacterized protein.	0.925
LIG4	RAD50	ENSGALP00000027179	ENSGALP00000039135	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	Zinc-hook domain-containing protein.	0.590
LIG4	RAD51B	ENSGALP00000027179	ENSGALP00000068967	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	RAD51 paralog B.	0.650
LIG4	RAD51C	ENSGALP00000027179	ENSGALP00000048159	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	RAD51 paralog C.	0.657
LIG4	RAD52	ENSGALP00000027179	ENSGALP00000063584	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination.	DNA repair protein RAD52 homolog; Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase (By similarity).	0.968
RAD50	BRCA2	ENSGALP00000039135	ENSGALP00000027524	Zinc-hook domain-containing protein.	Tower domain-containing protein.	0.608
RAD50	EXO1	ENSGALP00000039135	ENSGALP00000017465	Zinc-hook domain-containing protein.	Uncharacterized protein.	0.884