20 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CSTF3	Suf domain-containing protein. (718 aa)
	SRSF3	RRM domain-containing protein. (164 aa)
	SSU72	RNA polymerase II subunit A C-terminal domain phosphatase SSU72; May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination; Belongs to the SSU72 phosphatase family. (194 aa)
	SUB1	Activated RNA polymerase II transcriptional coactivator p15; General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity). (126 aa)
	GGA2	Uncharacterized protein. (490 aa)
	CSTF1	Cleavage stimulation factor subunit 1. (537 aa)
	CPSF2	Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
	FIP1L1	Fip1 domain-containing protein. (545 aa)
	PCF11	PCF11 cleavage and polyadenylation factor subunit. (1690 aa)
	BZW1	Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly. (418 aa)
	RPL21	Ribosomal protein L21. (164 aa)
	HNRNPH2	Heterogeneous nuclear ribonucleoprotein H1-like protein. (519 aa)
	PAPOLB	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (737 aa)
	CPSF6	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (582 aa)
	PTBP1	Uncharacterized protein. (556 aa)
	LMNA-2	Lamin-B2; Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin; Belongs to the intermediate filament family. (658 aa)
	U2AF2	U2 small nuclear RNA auxiliary factor 2. (699 aa)
	UBP1	Upstream binding protein 1. (529 aa)
	CSTF2	RRM domain-containing protein. (573 aa)
	PABPN1	RRM domain-containing protein. (474 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BZW1	RPL21	ENSGALP00000032837	ENSGALP00000043944	Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly.	Ribosomal protein L21.	0.608
BZW1	UBP1	ENSGALP00000032837	ENSGALP00000070907	Basic leucine zipper and W2 domain-containing protein 1; Enhances histone H4 gene transcription but does not seem to bind DNA directly.	Upstream binding protein 1.	0.616
CPSF2	CPSF6	ENSGALP00000017517	ENSGALP00000049306	Cleavage and polyadenylation specificity factor subunit 2.	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	0.909
CPSF2	CSTF1	ENSGALP00000017517	ENSGALP00000012563	Cleavage and polyadenylation specificity factor subunit 2.	Cleavage stimulation factor subunit 1.	0.997
CPSF2	CSTF2	ENSGALP00000017517	ENSGALP00000072327	Cleavage and polyadenylation specificity factor subunit 2.	RRM domain-containing protein.	0.994
CPSF2	CSTF3	ENSGALP00000017517	ENSGALP00000019081	Cleavage and polyadenylation specificity factor subunit 2.	Suf domain-containing protein.	0.978
CPSF2	FIP1L1	ENSGALP00000017517	ENSGALP00000022557	Cleavage and polyadenylation specificity factor subunit 2.	Fip1 domain-containing protein.	0.997
CPSF2	PABPN1	ENSGALP00000017517	ENSGALP00000072793	Cleavage and polyadenylation specificity factor subunit 2.	RRM domain-containing protein.	0.800
CPSF2	PAPOLB	ENSGALP00000017517	ENSGALP00000048061	Cleavage and polyadenylation specificity factor subunit 2.	Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's.	0.990
CPSF2	PCF11	ENSGALP00000017517	ENSGALP00000027831	Cleavage and polyadenylation specificity factor subunit 2.	PCF11 cleavage and polyadenylation factor subunit.	0.999
CPSF2	SRSF3	ENSGALP00000017517	ENSGALP00000000734	Cleavage and polyadenylation specificity factor subunit 2.	RRM domain-containing protein.	0.467
CPSF2	SSU72	ENSGALP00000017517	ENSGALP00000002256	Cleavage and polyadenylation specificity factor subunit 2.	RNA polymerase II subunit A C-terminal domain phosphatase SSU72; May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination; Belongs to the SSU72 phosphatase family.	0.986
CPSF2	SUB1	ENSGALP00000017517	ENSGALP00000005126	Cleavage and polyadenylation specificity factor subunit 2.	Activated RNA polymerase II transcriptional coactivator p15; General coactivator that functions cooperatively with TAFs and mediates functional interactions between upstream activators and the general transcriptional machinery. May be involved in stabilizing the multiprotein transcription complex. Binds single-stranded DNA. Also binds, in vitro, non-specifically to double-stranded DNA (ds DNA) (By similarity).	0.444
CPSF2	U2AF2	ENSGALP00000017517	ENSGALP00000070353	Cleavage and polyadenylation specificity factor subunit 2.	U2 small nuclear RNA auxiliary factor 2.	0.406
CPSF6	CPSF2	ENSGALP00000049306	ENSGALP00000017517	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Cleavage and polyadenylation specificity factor subunit 2.	0.909
CPSF6	CSTF1	ENSGALP00000049306	ENSGALP00000012563	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Cleavage stimulation factor subunit 1.	0.876
CPSF6	CSTF2	ENSGALP00000049306	ENSGALP00000072327	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	RRM domain-containing protein.	0.855
CPSF6	CSTF3	ENSGALP00000049306	ENSGALP00000019081	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Suf domain-containing protein.	0.795
CPSF6	FIP1L1	ENSGALP00000049306	ENSGALP00000022557	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Fip1 domain-containing protein.	0.784
CPSF6	HNRNPH2	ENSGALP00000049306	ENSGALP00000045256	Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]	Heterogeneous nuclear ribonucleoprotein H1-like protein.	0.690