8 items (Gallus gallus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	ACTB	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (375 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1402 aa)
	SST	Somatostatin-14; Somatostatin inhibits the release of somatotropin. (116 aa)
	GAL	Galanin variant 1. (141 aa)
	DBH	Dopamine beta-hydroxylase. (584 aa)
	TH	Tyrosine hydroxylase. (491 aa)
	NOS1	Nitric oxide synthase; Produces nitric oxide (NO). (1435 aa)
	ACTA2	Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (377 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA2	ACTB	ENSGALP00000067749	ENSGALP00000060844	Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.420
ACTB	ACTA2	ENSGALP00000060844	ENSGALP00000067749	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Actin, aortic smooth muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family.	0.420
ACTB	SST	ENSGALP00000060844	ENSGALP00000011889	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.539
ACTB	TH	ENSGALP00000060844	ENSGALP00000051175	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Tyrosine hydroxylase.	0.710
DBH	GAL	ENSGALP00000047529	ENSGALP00000042337	Dopamine beta-hydroxylase.	Galanin variant 1.	0.792
DBH	SST	ENSGALP00000047529	ENSGALP00000011889	Dopamine beta-hydroxylase.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.486
DBH	TH	ENSGALP00000047529	ENSGALP00000051175	Dopamine beta-hydroxylase.	Tyrosine hydroxylase.	0.970
GAL	DBH	ENSGALP00000042337	ENSGALP00000047529	Galanin variant 1.	Dopamine beta-hydroxylase.	0.792
GAL	SST	ENSGALP00000042337	ENSGALP00000011889	Galanin variant 1.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.939
GAL	TH	ENSGALP00000042337	ENSGALP00000051175	Galanin variant 1.	Tyrosine hydroxylase.	0.810
NOS1	NOS3	ENSGALP00000057794	ENSGALP00000073760	Nitric oxide synthase; Produces nitric oxide (NO).	Nitric oxide synthase; Produces nitric oxide (NO).	0.902
NOS3	NOS1	ENSGALP00000073760	ENSGALP00000057794	Nitric oxide synthase; Produces nitric oxide (NO).	Nitric oxide synthase; Produces nitric oxide (NO).	0.902
SST	ACTB	ENSGALP00000011889	ENSGALP00000060844	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.539
SST	DBH	ENSGALP00000011889	ENSGALP00000047529	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Dopamine beta-hydroxylase.	0.486
SST	GAL	ENSGALP00000011889	ENSGALP00000042337	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Galanin variant 1.	0.939
SST	TH	ENSGALP00000011889	ENSGALP00000051175	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Tyrosine hydroxylase.	0.740
TH	ACTB	ENSGALP00000051175	ENSGALP00000060844	Tyrosine hydroxylase.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.710
TH	DBH	ENSGALP00000051175	ENSGALP00000047529	Tyrosine hydroxylase.	Dopamine beta-hydroxylase.	0.970
TH	GAL	ENSGALP00000051175	ENSGALP00000042337	Tyrosine hydroxylase.	Galanin variant 1.	0.810
TH	SST	ENSGALP00000051175	ENSGALP00000011889	Tyrosine hydroxylase.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.740