4 items (Gallus gallus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (107 aa)
	POMC	Uncharacterized protein. (251 aa)
	SST	Somatostatin-14; Somatostatin inhibits the release of somatotropin. (116 aa)
	AGRP	Agouti-related protein. (233 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGRP	INS	ENSGALP00000003505	ENSGALP00000010567	Agouti-related protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.860
AGRP	POMC	ENSGALP00000003505	ENSGALP00000063133	Agouti-related protein.	Uncharacterized protein.	0.985
AGRP	SST	ENSGALP00000003505	ENSGALP00000011889	Agouti-related protein.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.515
INS	AGRP	ENSGALP00000010567	ENSGALP00000003505	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Agouti-related protein.	0.860
INS	POMC	ENSGALP00000010567	ENSGALP00000063133	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.861
INS	SST	ENSGALP00000010567	ENSGALP00000011889	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.943
POMC	AGRP	ENSGALP00000063133	ENSGALP00000003505	Uncharacterized protein.	Agouti-related protein.	0.985
POMC	INS	ENSGALP00000063133	ENSGALP00000010567	Uncharacterized protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.861
POMC	SST	ENSGALP00000063133	ENSGALP00000011889	Uncharacterized protein.	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	0.912
SST	AGRP	ENSGALP00000011889	ENSGALP00000003505	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Agouti-related protein.	0.515
SST	INS	ENSGALP00000011889	ENSGALP00000010567	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.943
SST	POMC	ENSGALP00000011889	ENSGALP00000063133	Somatostatin-14; Somatostatin inhibits the release of somatotropin.	Uncharacterized protein.	0.912