(10 nodes) (2011) Bioactive peptides derived from vascular endothelial cell extracellular matrices promote microvascular morphogenesis and wound healing in vitro. network (Gallus gallus)

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Your Input:
	EGF	Uncharacterized protein. (1283 aa)
	ALB	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family. (565 aa)
	FGF2	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis; Belongs to the heparin-binding growth factors family. (158 aa)
	MMP1	Matrix metallopeptidase 1. (466 aa)
	FBN1	Fibrillin 1. (2861 aa)
	FN1	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity). (2526 aa)
	TENM4	Uncharacterized protein. (2766 aa)
	DCN	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (357 aa)
	ELN	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely. (811 aa)
	COL3A1	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen. (1460 aa)

Your Current Organism:

Gallus gallus

NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	COL3A1	ENSGALP00000044604	ENSGALP00000051057	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.971
ALB	EGF	ENSGALP00000044604	ENSGALP00000044972	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Uncharacterized protein.	0.844
ALB	ELN	ENSGALP00000044604	ENSGALP00000069288	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.	0.632
ALB	FGF2	ENSGALP00000044604	ENSGALP00000031519	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis; Belongs to the heparin-binding growth factors family.	0.844
ALB	FN1	ENSGALP00000044604	ENSGALP00000005653	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity).	0.671
COL3A1	ALB	ENSGALP00000051057	ENSGALP00000044604	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood; Belongs to the ALB/AFP/VDB family.	0.971
COL3A1	DCN	ENSGALP00000051057	ENSGALP00000062069	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.985
COL3A1	EGF	ENSGALP00000051057	ENSGALP00000044972	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Uncharacterized protein.	0.848
COL3A1	ELN	ENSGALP00000051057	ENSGALP00000069288	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.	0.999
COL3A1	FBN1	ENSGALP00000051057	ENSGALP00000007941	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Fibrillin 1.	0.872
COL3A1	FGF2	ENSGALP00000051057	ENSGALP00000031519	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis; Belongs to the heparin-binding growth factors family.	0.951
COL3A1	FN1	ENSGALP00000051057	ENSGALP00000005653	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity).	0.999
COL3A1	MMP1	ENSGALP00000051057	ENSGALP00000027716	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	Matrix metallopeptidase 1.	0.751
DCN	COL3A1	ENSGALP00000062069	ENSGALP00000051057	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Collagen alpha-1(III) chain; Collagen type III occurs in most soft connective tissues along with type I collagen.	0.985
DCN	EGF	ENSGALP00000062069	ENSGALP00000044972	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Uncharacterized protein.	0.759
DCN	ELN	ENSGALP00000062069	ENSGALP00000069288	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Elastin; Major structural protein of tissues such as aorta and nuchal ligament, which must expand rapidly and recover completely.	0.926
DCN	FBN1	ENSGALP00000062069	ENSGALP00000007941	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibrillin 1.	0.900
DCN	FGF2	ENSGALP00000062069	ENSGALP00000031519	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis; Belongs to the heparin-binding growth factors family.	0.557
DCN	FN1	ENSGALP00000062069	ENSGALP00000005653	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. May be involved in osteoblast compaction (By similarity).	0.835
DCN	MMP1	ENSGALP00000062069	ENSGALP00000027716	Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Matrix metallopeptidase 1.	0.436