STRINGSTRING
PCF11 PCF11 PABPN1 PABPN1 NUDT21 NUDT21 CSTF2 CSTF2 PABPC4 PABPC4 PPP1CA PPP1CA CPSF6 CPSF6 PAPOLB PAPOLB PABPC1 PABPC1 PPP1CB PPP1CB CPSF3 CPSF3 FIP1L1 FIP1L1 CPSF2 CPSF2 PAPOLG PAPOLG CSTF1 CSTF1 CPSF4 CPSF4 LACTB LACTB SSU72 SSU72
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCF11PCF11 cleavage and polyadenylation factor subunit. (1690 aa)
PABPN1RRM domain-containing protein. (474 aa)
NUDT21Nudix hydrolase domain-containing protein. (473 aa)
CSTF2RRM domain-containing protein. (573 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (630 aa)
PPP1CAProtein phosphatase 1 catalytic subunit alpha. (384 aa)
CPSF6Cleavage and polyadenylation specificity factor subunit 6; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (582 aa)
PAPOLBPoly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (737 aa)
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (637 aa)
PPP1CBSerine/threonine-protein phosphatase PP1-beta catalytic subunit; Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity; Belongs to the PPP phosphatase family. PP-1 subfamily. (327 aa)
CPSF3Cleavage and polyadenylation specific factor 3. (691 aa)
FIP1L1Fip1 domain-containing protein. (545 aa)
CPSF2Cleavage and polyadenylation specificity factor subunit 2. (782 aa)
PAPOLGPoly(A) polymerase gamma. (722 aa)
CSTF1Cleavage stimulation factor subunit 1. (537 aa)
CPSF4Uncharacterized protein. (243 aa)
LACTBUncharacterized protein. (520 aa)
SSU72RNA polymerase II subunit A C-terminal domain phosphatase SSU72; May be involved in the C-terminal domain of RNA polymerase II dephosphorylation, RNA processing and termination; Belongs to the SSU72 phosphatase family. (194 aa)
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus domesticus, Gallus gallus domesticus, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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